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UCM 608
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Catalog No. T22499Cas No. 151889-03-1
Alias UCM608, 2-Phenylmelatonin
UCM 608 (2-Phenylmelatonin) is an antagonist of melatonin-induced contractile responses at low concentrations and induces an increase in GDP-GTP exchange.
UCM 608
🥰Excellent
Purity: 98.88%
Catalog No. T22499Alias UCM608, 2-PhenylmelatoninCas No. 151889-03-1
UCM 608 (2-Phenylmelatonin) is an antagonist of melatonin-induced contractile responses at low concentrations and induces an increase in GDP-GTP exchange.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $46 | In Stock | In Stock | |
| 5 mg | $72 | In Stock | In Stock | |
| 10 mg | $98 | In Stock | In Stock | |
| 25 mg | $168 | In Stock | In Stock | |
| 50 mg | $247 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.88%
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Product Introduction
Bioactivity
Chemical Properties
| Description | UCM 608 (2-Phenylmelatonin) is an antagonist of melatonin-induced contractile responses at low concentrations and induces an increase in GDP-GTP exchange. |
| Targets&IC50 | MT2 receptor:10.4 (pKi), MT1 receptor:10.7 (pKi) |
| In vitro | UCM 608 is an agonist with high affinity for melatonin membrane receptors. Its pKi values for MT1 and MT2 receptors are 10.7 and 10.4, respectively. [1] |
| Synonyms | UCM608, 2-Phenylmelatonin |
| Molecular Weight | 308.37 |
| Formula | C19H20N2O2 |
| Cas No. | 151889-03-1 |
| Smiles | O=C(NCCC=1C=2C=C(OC)C=CC2NC1C=3C=CC=CC3)C |
| Relative Density. | 1.172g/cm3 |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20.00 mg/mL (64.86 mM), Sonication is recommended. Ethanol: 20.00 mg/mL (64.86 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO/Ethanol
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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