hsp70

HSP70 HSPA1A Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P0DMV8-1.

Expression system: E. coli
Length: 3-389, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 3-389, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-674, Full Length
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 1-638, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-638, Full Length
Activity: Not Tested

HSP70 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.6 kDa and the accession number is A6KTP2.

HSP70 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.2 kDa and the accession number is A8K5I0.

Expression system: HEK293 Cells
Length: 2-641, Partial
Activity: Not Tested

DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. DNAJB1 regulates cellular processes by aiding in the folding, transport and assembly. DNAJB1 contains a J-domain which controls interaction with the ATPase domain of DnaK. DNAJB1 interacts with HSP70 and can stimulate its ATPase activity. In addition, DNAJB1 stimulates the association between HSC70 and HIP.

Expression system: E. coli
Length: 1-303, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 20-655, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 20-655, Full Length of Mature Protein
Activity: Not Tested

Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40 Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.

Expression system: E. coli
Length: 1-317, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-211, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 19-182, Full Length of Mature Protein
Activity: Not Tested

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.

Expression system: HEK293 Cells
Length: 22-196, Full Length of Mature Protein
Activity: ELISA