competitively — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7558	CID-1067700		Ras
	CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).		Ras
T21213	Benzylurea	AI3-61350,Benzylcarbamide,Phenylmethylurea,1-Benzylurea,N-Benzylurea	Others
	Benzylurea (AI3-61350) competitively inhibits dehydrogenase/cytokinin oxidase.		Others
T2697	KN-93		CaMK , Autophagy
	KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.		CaMK , Autophagy
TN1081	Hirsuteine		Dopamine Receptor
	Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.		Dopamine Receptor
T0215	Losartan potassium	DuP-753 potassium,MK 954,DuP 753	RAAS
	Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.		RAAS
T0123	Sulfanilamide	Sulphanilamide,UK-124	Antibacterial , Antibiotic , Autophagy
	Sulfanilamide (UK-124) can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.		Antibacterial , Antibiotic , Autophagy
T60390	PI-55	6-(2-hydroxy-3-methylbenzylamino)purine	Others
	PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis recept...		Others
T8862	ML 254		GluR
	ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas...		GluR
T6094	MK-2461	MK2461	c-Met/HGFR
	MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with an average inhibitory concentration (IC50) of 2.5 nM.		c-Met/HGFR
T2353	BRD7116	BRD7716	DNA gyrase , Antibacterial
	BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.		DNA gyrase , Antibacterial
T1933	NVP 231		Apoptosis , ERK
	NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.		Apoptosis , ERK
T11285	FIDAS-5		Others
	FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.		Others
T6999	Teneligliptin hydrobromide	Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)	Others , Proteasome , DPP-4
	Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 ...		Others , Proteasome , DPP-4
T5160	SR3335	ML 176	ROR
	SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).		ROR
T11001L1	N-Desethyl Chloroquine Hydrochloride	(±)-Desethylchloroquine 2HCl
	N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.
T0380	Bicalutamide	ICI-176334	Androgen Receptor , Autophagy
	Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.		Androgen Receptor , Autophagy
T1876	Kobe0065		Apoptosis , Raf , Ras
	Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; shows potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.		Apoptosis , Raf , Ras
T4498	Stiripentol	BCX2600,Diacomit	P450
	Stiripentol (BCX2600) (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM...		P450
T0797	Cimetidine	SKF-92334	Histamine Receptor
	Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEP...		Histamine Receptor
T19032	Nitro blue tetrazolium chloride	NBT	NO Synthase
	Nitro blue tetrazolium chloride (NBT) is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 M). A well-known scavenger of superoxide anions.Nitro blue tetrazolium chloride, a subst...		NO Synthase