cephalosporin

Cefdinir (FK-482) is a third-generation, semi-synthetic cephalosporin antibiotic effective against common bacterial infections of the ear, sinus, throat, and skin.

Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date, no severe side effects have been noted.

Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.

Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity.

Ceftobiprole medocaril (BAL5788), the parenteral prodrug of Ceftobiprole, is a broad-spectrum cephalosporin effective against Methicillin-resistant Staphylococcus aureus (MRSA).

Cefoselis Sulfate is a widely used beta-lactam antibiotic.

Ceftobiprole (Ro 63-9141) is a β-lactam antibacterial agent that exhibits potent bactericidal activity by binding to PBPs, inhibiting transpeptidation and formation of bacterial cell walls, leading to cell lysis and death, with a MIC90 value of 2 μg/mL against methicillin-resistant Staphylococcus aureus.

Cephalosporin Canalog-1 is an analogue of Cephalosporin C, which exhibits relatively weak resistance to both Gram-positive and Gram-negative bacteria. Cephalosporin C is stable against penicillinase but can be decomposed by cephalosporinase. Through hydrolysis, its side chain can be removed to yield 7-amino-cefenoic acid (7-ACA), an essential raw material for producing semi-synthetic cephalosporins.

Trans-substituted cephalosporin is an efficient inhibitor of NDM-1, demonstrating an IC50 value of 0.13 μM.

Cephalosporin Canalog-1 (sodium) is an analogue of Cephalosporin C, which demonstrates weak resistance against both Gram-positive and Gram-negative bacteria. It is stable to penicillinase and can be broken down by cephalosporinase. Hydrolysis removes the side chain to yield 7-amino-cefenoic acid (7-ACA), a crucial precursor for synthesizing semi-synthetic cephalosporins.

Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.

Cephalosporin P1 is a biochemical.

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 µM), and this inhibition was largely attributable to the presence of zinc.

AMG 118 Immobilized cephalosporin C acylase is an enzyme in immobilized form used primarily in industrial catalysis for the production of the vital pharmaceutical intermediate, 7-aminocephalosporanic acid (7-ACA). The CPC acylase it contains is a highly specialized β-lactam acylase or peptidase capable of cleaving the amide bond within β-lactams.

Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

AMK-EX (Immobilized cephalosporin C or 7-ACA esterase) is an immobilized enzyme where cephalosporin C/7-ACA esterases are enzymes capable of hydrolyzing cephalosporin or 7-ACA ester bonds. Immobilized enzymes involve a technique that anchors enzymes onto carriers, facilitating easy separation and recovery, while enhancing the enzyme's stability, activity, and reusability.

Cephalosporinase, bacillus, are enzymes produced by Bacillus; these enzymes inactivate and degrade the effectiveness of cephalosporin antibiotics. Cephalosporins are a class of β-lactam antibiotics widely used to treat bacterial infections [1].

Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.

Ceftolozane sulfate (FR-264205/CXA-101) is a cephalosporin antibiotic, a penicillin-binding protein (PBP) inhibitor with antipseudomonal activity, used for infection research including pneumonia.

Sulopenem (CP-70429) is an orally active gastrointestinal-external cephalosporin antibiotic with broad-spectrum antibacterial activity. It inhibits Gram-positive and Gram-negative bacteria and can be used in bacterial infection research.

Cefetamet sodium (Ro 15-8074/001) is an orally available cephalosporin antibiotic with antimicrobial activity and is used to study cirrhosis of the liver and lung infections.

Cefazaflur is a novel semi-synthetic cephalosporin derivative that can be used as an Antibiotic agent.

Cefuzonam is a novel cephalosporin with anti-inflammatory and antibacterial activity that can be used in studies of respiratory tract infections, tonsillitis, and hepatobiliary infections.

Cefpiramide acid (Cefpiramidum) is a third-generation cephalosporin antibiotic.