anti-pd-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35394	Sintilimab (anti-PD-1)	IBI308,Sintilimab (anti-PD-1)	PD-1/PD-L1
	Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i...		PD-1/PD-L1
T35396	Spartalizumab (anti-PD-1)		PD-1/PD-L1
	Spartalizumab (anti-PD-1) is a useful organic compound for research related to life sciences and the catalog number is T35396.		PD-1/PD-L1
T78269	Anti-Mouse PD-1 Antibody (RMP1-14)		PD-1/PD-L1
	RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.		PD-1/PD-L1
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T76750	Cemiplimab	REGN-2810,SAR-439684	Others
	Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...		Others
T9902	Atezolizumab		Apoptosis , PD-1/PD-L1 , Autophagy
	Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.		Apoptosis , PD-1/PD-L1 , Autophagy
T9907	Nivolumab		PD-1/PD-L1
	Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ...		PD-1/PD-L1
T37535	Camrelizumab	SHR-1210
	Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up to 3 nM and is inhibitory to PD-1/PD-L1 with an IC50 of 0.7...
T76717	Serplulimab	HLX 10	COX
	Serplulimab (HLX 10) is a humanized monoclonal anti-antibody to PD-1. Serplulimab has antitumor activity and can be used in small cell lung cancer and esophageal squamous cell carcinoma.		COX
T77433	Feladilimab	GSK3359609	COX , PD-1/PD-L1
	Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L1 expression. Feladilimab has anti-tumor activity and can b...		COX , PD-1/PD-L1
TN1051	1-Caffeoylquinic acid		NF-κB
	1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.		NF-κB
T77068	Lodapolimab
	Lodapolimab (LY3300054) is an IgGλ anti- PD-1 monoclonal antibody [1] .
T79136	DGKζ-IN-1
	DGKζ-IN-1 (compound 9) is a DGKζ inhibitor with potential applications in cancer research, particularly for studying immunocyte activation and resistance to anti-PD-1/anti-PD-L1 antibody therapies [1].
T77024	Gilvetmab
	Gilvetmab, a potent caninized anti-PD-1 monoclonal antibody, effectively inhibits the interaction between PD-1 and its ligand PDL-1 [1].
T63329	PD-1/PD-L1-IN-25
	PD-1/PD-L1-IN-25 is an inhibitor of PD-1/PD-L1 interaction (IC50: 16.17 nM) that effectively activates anti-tumor immunity of T cells in PBMCs. PD-1/PD-L1-IN-25 can be used to study cancer.
T79825	DGKζ-IN-4
	DGKζ-IN-4 is a DGK-zeta inhibitor employed as an active ingredient in pharmaceutical formulations designed to treat cancers linked to immune cell activation or those resistant to anti-PD-1/anti-PD-L1 antibody treatments ...
T76715	Envafolimab
	Envafolimab (ASC 22; KN 035), a recombinant humanized single-domain anti-PD-L1 antibody, integrates the anti-PD-L1 domain with the Fc fragment of the human IgG1 antibody. It inhibits the PD-L1 and PD-1 interaction with a...
T76708	Penpulimab
	Penpulimab, an anti-PD-1 monoclonal antibody featuring an IgG1 backbone, possesses antitumor activities [1].
T77180	Retifanlimab
	Retifanlimab, an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb), is utilized in the research of gastroesophageal adenocarcinoma (GEA) [1].