ac 4

Ac4ManNDAz is a cell-permeable photocrosslinking probe that is a precursor to photocrosslinked sialic acid, which attaches to cell surface α2-6-conjugated sialic acid and produces photocrosslinking via sialic acid.

DiBAC4(3) is a voltage-sensitive fluorescent dye (λem=505 nm, λex=490 nm).

DiBaC4(5) is a fluorescent, voltage-sensitive dye used for monitoring transmembrane potentials in Papain-dissociated retinal cells from adult zebrafish exposed to GABAergic ligands. DiBaC4(5) is noted for its potential-sensitive fluorescence properties [1].

Ac-Orn-Phe-Arg-AMC is an effective fluorescent substrate for cd-Tryptase and β1-Tryptase. This compound releases 7-amino-4-methylcoumarin (AMC), which is utilized for fluorescence detection.

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively.

Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence quantifies the activity of the β5i/LMP7 subunit. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

Ac-LEVD-pNA, a chromogenic substrate for caspase-4, can be used to detect caspase-4 activity [1].

Ac-WEHD-pNA serves as a colorimetric substrate for caspases 1, 4, 5, and 14, widely used to assess caspase activity [1].

Ac-YEVD-AMC, a fluorescent substrate of caspase-1/11, releases amino-4-methylcoumarin (AMC) for fluorescence detection when treated with cell lysate [1].