neutral

Neutral red is a vital dye, is used as an indicator and biological stain.

Nile Red (Nile Blue A oxazone) is a strongly fluorescent stain used for the detection of intracellular lipid droplets in the presence of a hydrophobic environment.

BODIPY 493/503 (Pyrromethene 546) is a lipophilic fluorescent probe with Ex/Em of 493/503 nm. BODIPY 493/503 localizes to polar lipids and can be used to label cellular neutral lipid contents and for live and fixed cell applications.

Cyanine3 NHS Ester Chloride is an amine-reactive orange-red fluorescent dye and the NHS ester derivative of Cyanine3, supplied as a chloride salt. Its N-hydroxysuccinimide (NHS) ester reacts efficiently with primary amines on proteins, antibodies, or other biomolecules under neutral to slightly basic conditions, forming stable amide bonds. This dye is widely used for cellular labeling, flow cytometry, and biomolecular staining studies.

2-Aminobenzamide, a neutral and stable compound, is widely used as a fluorescent tag in glycan analysis and serves as the starting material for several important reactions.

Compound 2f, chemically known as 4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one, is a selenium alcohol fluorescent probe designed on the nucleophilic aromatic substitution mechanism. It exhibits selective recognition of selenols in neutral aqueous solutions without significant interference from biological thiols, amines, or alcohols. This compound is utilized for quantifying selenium content in selenoproteins and imaging the activity of endogenous selenols in living cells.

BODIPY 493/503 carboxylic acid is a green BODIPY fluorescent dye with lipophilic properties, commonly used for staining lipids, membranes, and other neutral lipids in live and fixed cells.

BODIPY 650/665 (NHS ester) is a far-red/near-infrared fluorescent dye with excitation and emission wavelengths of 646/660 nm. It is used to label neutral lipids in live or fixed cells and is commonly employed in studies of adipocyte differentiation and lipid metabolism. NHS ester can specifically bind to primary amine groups (-NH₂) on molecules such as proteins and peptides, forming stable amide bonds.

Cy5-bifunctional dye potassium is a water-soluble bifunctional dye with two NHS ester terminal groups. The NHS ester can react specifically and efficiently under neutral or mildly alkaline conditions with primary amines, such as lysine residue side chains or amino silane-coated surfaces, forming covalent bonds. This dye is applicable for amine cross-linking and other advanced labeling applications.

FAM NHS ester, 6-isomer, is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines, such as lysine residue side chains or aminosilane-coated surfaces, under neutral or mildly basic conditions to form covalent bonds.

BDP 650/665 X NHS ester is a hydrophobic fluorophore featuring an NHS ester. Under neutral or slightly basic conditions, the NHS ester reacts specifically and efficiently with primary amines like lysine residue side chains or amino silane-coated surfaces, forming covalent bonds. BDP 650/665 X NHS ester is applicable for labeling lipids, oligonucleotides, peptides, and a variety of other macromolecules and small molecules.

C12-NBD Sphinganine is a fluorescent substrate for ceramidase, utilized to assess the activity of alkaline and neutral ceramidases from various sources.

C6 NBD Sphingomyelin (d18:1/6:0) (NBD SM(d18:1/6:0)) is a fluorescent short-chain analog of Sphingomyelin. It exhibits activity of neutral sphingomyelinase (N-SMase).

Sulfo-Cyanine3 Maleimide is an orange fluorescent dye containing a maleimide group that reacts specifically with thiol (-SH) groups on proteins, antibodies, and other biomolecules, forming stable thioether bonds in neutral buffers. The sulfonate modification imparts excellent water solubility, allowing labeling of solvent-sensitive or unstable proteins without organic co-solvents. This dye is widely used for fluorescence imaging, flow cytometry, and functional protein labeling studies.

Sulfo-Cyanine5.5 NHS Ester is a near-infrared fluorescent dye belonging to the cyanine dye family. Its NHS ester group reacts efficiently with primary amines on proteins, antibodies, and other biomolecules under neutral to slightly basic conditions, forming stable amide bonds. The dye exhibits good water solubility and biocompatibility, making it widely used for protein labeling, multicolor fluorescence analysis, and the development of in vivo imaging probes.

BODIPY 558/568 C12 (Red C12) is an intracellular BODIPY dye that crosses cell membranes and is an orange-red fluorescent fatty acid that can be used to label living cells by localizing on intracellular neutral lipids for specific staining.

10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester derivative of acridinium esters, serves as a fluorescent dye exhibiting chemiluminescence in neutral conditions and is utilized in the quantification of hydrogen peroxide [1].

Bdp TR NHS Ester is a chemiluminescent coupling agent featuring an extended excited state lifetime, ideal for applications in immunoassays, microscopy, and fluorescence polarization analysis. This compound efficiently and specifically reacts with primary amine groups, including lysine residues or amino silane-coated surfaces, facilitating covalent bond formation under neutral or mildly basic conditions [1].

4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by acidity and solvent properties. In near-neutral aqueous solutions, it predominates in a neutral molecular form, emitting strong fluorescence at 445 nm, whereas in weakly alkaline solutions, it primarily exists in an anionic form, resulting in even stronger fluorescence at the same wavelength [1] [2].

BODIPY 650/665 4C (BODIPY 650/665 analogue) is an analogue of BODIPY 650/665 in which the carbon chain linked to the NHS ester is four carbon atoms long. BODIPY 650/665 is a far-red/near-infrared fluorescent dye that can be used to label neutral lipids in live or fixed cells.

C6 NBD galactosylceramide, an active derivative of galactosylceramide tagged with fluorescent nitrobenzoxadiazole (NBD), serves as a substrate for neutral β-glycosylceramidase (GCase) in studies of intracellular localization and metabolism of galactosylceramide (Ex=nm, Em=525) [1].