MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.

Cat. No.	Product name	CAS No.	Purity
T67879	HMAO-B-IN-5	358343-63-2	98%
T67879	hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be...
T60932	MAO-B-IN-8	1638956-60-1	98%
T60932	MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neu...
T60891	AChE/BChE/MAO-B-IN-1	2416910-82-0	98%
T60891	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects o...
T77578	CHBO4	98991-32-3	98%
T77578	CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
T67789	Bazinaprine	94011-82-2	98%
T67789	Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong...
T27288	Esuprone	91406-11-0	98%
T27288	Esuprone is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.
T68069	Femoxetine	59859-58-4	98%
T68069	Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the ...
T32535	Ladostigil	209394-27-4	98%
T32535	Ladostigil is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 ...
T32208	Isogentisin	491-64-5	98%
T32208	Isogentisin, a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory ...
T10617	Brofaromine	63638-91-5	98%
T10617	Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate	67667-71-4	98%
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone	59443-02-6	98%
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate	83182-58-5	98%
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
T10079	MAO-IN-1	124991-40-8	98%
T10079	MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
TN4137	Glicoricone	161099-37-2	98%
TN4137	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T5470	LAZABEMIDE	103878-84-8	98%
T5470	LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T16770	Ro 41-1049 hydrochloride	127917-66-2	98%
T16770	Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
TN1099	Dihydroevocarpine	15266-35-0	98%
TN1099	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
TN2790	2'-O-Methylperlatolic acid	38968-07-9	98%
TN2790	2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN3024	4'-Demethyleucomin	34818-83-2	98%
TN3024