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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T32208 Isogentisin 491-64-5 95.1%
Isogentisin
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibi...
T10079 MAO-IN-1 124991-40-8 100%
MAO-IN-1
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
T10617 Brofaromine 63638-91-5 98%
Brofaromine
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
TN3294 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate 67667-71-4 98%
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN2553 1-Methyl-2-undecyl-4(1H)-quinolone 59443-02-6 98%
1-Methyl-2-undecyl-4(1H)-quinolone
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3300 8alpha-Tigloyloxyhirsutinolide 13-O-acetate 83182-58-5 98%
8alpha-Tigloyloxyhirsutinolide 13-O-acetate
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
TN4137 Glicoricone 161099-37-2 98%
Glicoricone
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T5470 LAZABEMIDE 103878-84-8 98%
LAZABEMIDE
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T16770 Ro 41-1049 hydrochloride 127917-66-2 98%
Ro 41-1049 hydrochloride
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
TN1099 Dihydroevocarpine 15266-35-0 98%
Dihydroevocarpine
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
TN2790 2'-O-Methylperlatolic acid 38968-07-9 98%
2'-O-Methylperlatolic acid
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN3024 4'-Demethyleucomin 34818-83-2 98%
4'-Demethyleucomin
4'-Demethyleucomin is a natural product for research related to life sciences. The catalog number is TN3024 and the CAS number is 34818-83-2.
TN3918 Echitovenidine 7222-35-7 98%
Echitovenidine
Echitovenidine shows monoamine oxidase inhibitor activity.
TN3116 5-Hydroxy-1-methoxyxanthone 27770-13-4 98%
5-Hydroxy-1-methoxyxanthone
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
TN3726 Cudraflavone B 19275-49-1 98%
Cudraflavone B
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
T18918 Azure B 531-55-5 BS
Azure B
Azure B (Azure B chloride) is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and...
T0751 Furazolidone 67-45-8 99.98%
Furazolidone
Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,...
T8907 Minaprine dihydrochloride 25953-17-7 99.97%
Minaprine dihydrochloride
Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment o...
T1711 Harmine 442-51-3 99.92%
Harmine
Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.
T71934 Atibeprone 153420-96-3 99.92%
Atibeprone
Atibeprone is a MAO-B inhibitor with antidepressant activity for the study of Parkinson's disease.
Isogentisin
T32208
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibi...
MAO-IN-1
T10079
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
Brofaromine
T10617
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
TN3294
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
1-Methyl-2-undecyl-4(1H)-quinolone
TN2553
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
8alpha-Tigloyloxyhirsutinolide 13-O-acetate
TN3300
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
Glicoricone
TN4137
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
LAZABEMIDE
T5470
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
Ro 41-1049 hydrochloride
T16770
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
Dihydroevocarpine
TN1099
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
2'-O-Methylperlatolic acid
TN2790
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
4'-Demethyleucomin
TN3024
4'-Demethyleucomin is a natural product for research related to life sciences. The catalog number is TN3024 and the CAS number is 34818-83-2.
Echitovenidine
TN3918
Echitovenidine shows monoamine oxidase inhibitor activity.
5-Hydroxy-1-methoxyxanthone
TN3116
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
Cudraflavone B
TN3726
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
Azure B
T18918
Azure B (Azure B chloride) is a cationic dye and the major metabolite of Methylene blue. Azure B is a selective, and reversible inhibitor of MAO-A (IC50s: 11 and...
Furazolidone
T0751
Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,...
Minaprine dihydrochloride
T8907
Minaprine dihydrochloride is a reversible MAO-A inhibitor; It weakly inhibit acetylcholinesterase. Minaprine dihydrochloride is an antidepressant for treatment o...
Harmine
T1711
Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.
Atibeprone
T71934
Atibeprone is a MAO-B inhibitor with antidepressant activity for the study of Parkinson's disease.
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TargetMol