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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Cat. No. Product name CAS No. Purity Chemical Structure
TN3294 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate 67667-71-4 98%
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN7211 Tetrahydroharmine 17019-01-1 98%
Tetrahydroharmine is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A...
T0338 Minaprine 25905-77-5 98%
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
TN3300 8alpha-Tigloyloxyhirsutinolide 13-O-acetate 83182-58-5 98%
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
T15023 CX-157 205187-53-7 98%
CX-157 is a reversible monoamine oxidase-A (MAO-A) inhibitor (EC50:19.3 ng/mL).
T10079 MAO-IN-1 124991-40-8 98%
MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
TN2790 2'-O-Methylperlatolic acid 38968-07-9 98%
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
T10146 4-Hydroxyderricin 55912-03-3 98%
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B inhibitor (IC50: 3.43 μM). It also mildly inhibits DBH ...
TN4137 Glicoricone 161099-37-2 98%
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
TN2553 1-Methyl-2-undecyl-4(1H)-quinolone 59443-02-6 98%
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3024 4'-Demethyleucomin 34818-83-2 98%
T5470 LAZABEMIDE 103878-84-8 98%
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
TN3116 5-Hydroxy-1-methoxyxanthone 27770-13-4 98%
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
T10617 Brofaromine 63638-91-5 98%
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
TN3726 Cudraflavone B 19275-49-1 98%
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
TN1099 Dihydroevocarpine 15266-35-0 98%
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
T16770 Ro 41-1049 hydrochloride 127917-66-2 98%
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
TN3918 Echitovenidine 7222-35-7 98%
Echitovenidine shows monoamine oxidase inhibitor activity.
T24679 PSB-1434 1619884-65-9 98%
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
T15010 CR4056 1004997-71-0 98%
CR4056 is a selective inhibitor of MAO-A with IC50 of 202.7 nM and a ligand of I2-imidazoline receptor with IC50 of 596 nM.
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
TN3294
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
Tetrahydroharmine
TN7211
Tetrahydroharmine is a natural product found in the stems and large branches of Banisteriopsis caapi cultivar Da Vine. Tetrahydroharmine is a Monoamine oxidase A...
Minaprine
T0338
Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
8alpha-Tigloyloxyhirsutinolide 13-O-acetate
TN3300
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
CX-157
T15023
CX-157 is a reversible monoamine oxidase-A (MAO-A) inhibitor (EC50:19.3 ng/mL).
MAO-IN-1
T10079
MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
2'-O-Methylperlatolic acid
TN2790
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
4-Hydroxyderricin
T10146
4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B inhibitor (IC50: 3.43 μM). It also mildly inhibits DBH ...
Glicoricone
TN4137
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
1-Methyl-2-undecyl-4(1H)-quinolone
TN2553
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
4'-Demethyleucomin
TN3024
LAZABEMIDE
T5470
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
5-Hydroxy-1-methoxyxanthone
TN3116
5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees o...
Brofaromine
T10617
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
Cudraflavone B
TN3726
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
Dihydroevocarpine
TN1099
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
Ro 41-1049 hydrochloride
T16770
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
Echitovenidine
TN3918
Echitovenidine shows monoamine oxidase inhibitor activity.
PSB-1434
T24679
PSB-1434 is a selective and competitive monoamine oxidase B inhibitor.
CR4056
T15010
CR4056 is a selective inhibitor of MAO-A with IC50 of 202.7 nM and a ligand of I2-imidazoline receptor with IC50 of 596 nM.
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