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MAO

Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs.
Cat. No. Product name CAS No. Purity Chemical Structure
T67879 HMAO-B-IN-5 358343-63-2 98%
hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be...
T60932 MAO-B-IN-8 1638956-60-1 98%
MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neu...
T60891 AChE/BChE/MAO-B-IN-1 2416910-82-0 98%
AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects o...
T77578 CHBO4 98991-32-3 98%
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
T67789 Bazinaprine 94011-82-2 98%
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong...
T27288 Esuprone 91406-11-0 98%
Esuprone is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.
T68069 Femoxetine 59859-58-4 98%
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the ...
T32535 Ladostigil 209394-27-4 98%
Ladostigil is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 ...
T32208 Isogentisin 491-64-5 98%
Isogentisin, a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory ...
T10617 Brofaromine 63638-91-5 98%
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
TN3294 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate 67667-71-4 98%
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN2553 1-Methyl-2-undecyl-4(1H)-quinolone 59443-02-6 98%
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
TN3300 8alpha-Tigloyloxyhirsutinolide 13-O-acetate 83182-58-5 98%
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
T10079 MAO-IN-1 124991-40-8 98%
MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
TN4137 Glicoricone 161099-37-2 98%
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
T5470 LAZABEMIDE 103878-84-8 98%
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T16770 Ro 41-1049 hydrochloride 127917-66-2 98%
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
TN1099 Dihydroevocarpine 15266-35-0 98%
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
TN2790 2'-O-Methylperlatolic acid 38968-07-9 98%
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
TN3024 4'-Demethyleucomin 34818-83-2 98%
hMAO-B-IN-5
T67879
hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be...
MAO-B-IN-8
T60932
MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neu...
AChE/BChE/MAO-B-IN-1
T60891
AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects o...
CHBO4
T77578
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the...
Bazinaprine
T67789
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong...
Esuprone
T27288
Esuprone is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.
Femoxetine
T68069
Femoxetine is a 5-HT inhibitor with antidepressant activity that potentiates morphine-induced anti-injury feelings and inhibits MAO-A and MAO-B required for the ...
Ladostigil
T32535
Ladostigil is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) with inhibitory effects on MAO-B and AChE, with IC50 ...
Isogentisin
T32208
Isogentisin, a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory ...
Brofaromine
T10617
Brofaromine (CGP 11305A) is an MAO inhibitor (IC50: 0.2 μM for MAO-A).
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
TN3294
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
1-Methyl-2-undecyl-4(1H)-quinolone
TN2553
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodi...
8alpha-Tigloyloxyhirsutinolide 13-O-acetate
TN3300
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has ...
MAO-IN-1
T10079
MAO-IN-1 is an inhibitor of monoamine oxidase B (MAO B; IC50: 20 nM).
Glicoricone
TN4137
Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
LAZABEMIDE
T5470
LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
Ro 41-1049 hydrochloride
T16770
Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (Kd: 16.5 and 64.4 nM, respectively).
Dihydroevocarpine
TN1099
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
2'-O-Methylperlatolic acid
TN2790
2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.
4'-Demethyleucomin
TN3024
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