Cannabinoid Receptor

Cannabinoid receptors are of a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body;[citation needed] plant cannabinoids (such as cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and phytocannabinoids (plant based cannabinoids) are lipophilic, such as fat soluble compounds.

Cat. No.	Product name	CAS No.	Purity
T14504	BAY 38-7271	212188-60-8	98%
T14504	BAY 38-7271 has strong neuroprotective properties.[1] BAY 38-7271 is selective and highly potent and cannabinoid CB1/CB2 receptor agonist. With Kis of 1.85 nM an...
T17027	Tedalinab	916591-01-0	98%
T17027	Tedalinab is an effective and selective cannabinoid receptor 2 agonist. Tedalinab has the potential for neuropathic pain and osteoarthritis treatment. Tedalinab ...
T10510	CB1 antagonist 1	890037-68-0	98%
T10510	CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and gast...
T13081	Taranabant racemate	701977-00-6	98%
T13081	Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.
T64394	GW 833972A	1092502-33-4	98%
T64394	GW 833972A is a selective CB2 receptor agonist.GW 833972A has an inhibitory effect on induced neural depolarization and on citric acid-induced cough in an animal...
T29930	AM-1235	335161-27-8	98%
T29930	AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.
T19705	JTE-907	282089-49-0	98%
T19705
T67896	CB2R/FAAH modulator-1	928892-60-8	98%
T67896	CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
T8511	TM38837	1253641-65-4	98%
T8511	TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
T24771	SCH-336	447459-51-0	98%
T24771	SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100...
TN5131	Tetrahydrocannabivarin	31262-37-0	98%
TN5131	Tetrahydrocannabivarin is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, th...
TN3575	(±)-Cannabichromene	20675-51-8	98%
TN3575	Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 ...
T14302	Olorinab	1268881-20-4	98%
T14302	Olorinab (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.
T9114	β-Caryophyllene	87-44-5	98%
T9114	β-Caryophyllene acts as an CB2 receptor agonist.
T1915	AM251	183232-66-8	98%
T1915	AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
T7375	A-836339	959746-77-1	98%
T7375	A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 recep...
T2635	Org 27569	868273-06-7	98%
T2635	Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and e...
T22009	CB2 receptor agonist 2	1314230-75-5	98%
T22009	CB2 receptor agonist 2 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and sel...
T37075	CB2R PAM	2244579-87-9	98%
T37075	CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive mutational modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]G...
T28468	PSNCBAM-1	877202-74-9	98%
T28468	PSNCBAM-1 is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.