contraction — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14865	Carboprost tromethamine		Prostaglandin Receptor
	Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.		Prostaglandin Receptor
T2176	2,3-Butanedione 2-Monoxime	Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.		Akt
T4054	Dantrolene sodium hemiheptahydrate	Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene	Calcium Channel , Autophagy
	Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from t...		Calcium Channel , Autophagy
T25372	EMD57033	EMD-57033,(+)-EMD 57033,EMD 57033	Calcium Channel , Carbonic Anhydrase
	EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiac/slow skeletal troponin C heterodimers to promote cardiac contraction.		Calcium Channel , Carbonic Anhydrase
T25719	Lidamidine	Lidamidina,Lidamidinum	Others
	Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscle contraction.		Others
T10101	Calcium channel-modulator-1		Others , Calcium Channel
	Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.		Others , Calcium Channel
T34280	Regrelor disodium	INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589	P2Y Receptor
	Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibits cell proliferation, and reduces inflammation.		P2Y Receptor
TP1883	[Lys5,MeLeu9,Nle10]-NKA(4-10)		Neurokinin receptor
	Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).		Neurokinin receptor
T28164	Nexopamil	LU49938,LU 49938,LU-49938	Calcium Channel , 5-HT Receptor
	Nexopamil (LU-49938) is a calcium channel antagonist and a 5-hydroxytryptamine 2A receptor antagonist. Nexopamil inhibits 5-HT-induced contraction and proliferation of mesenchymal cells.		Calcium Channel , 5-HT Receptor
TP2419	V-9-M Cholecystokinin nonapeptide	V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M	Beta Amyloid
	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal peptide that stimulates gallbladder contraction and pancreatic e...		Beta Amyloid
T3A2467	Allocryptopine	Thalictrimine,Fagarine I	Potassium Channel
	Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.		Potassium Channel
T20604L	Litorin acetate(55749-97-8 Free base)		Bombesin Receptor
	Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist. It stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the n...		Bombesin Receptor
TP2036L	DPDPE TFA (88373-73-3 free base)	DPDPE TFA	Opioid Receptor
	DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.		Opioid Receptor
T6S0109	Sipeimine	Kashmirine,Imperialine	Others
	1. Sipeimine (Kashmirine) has antiasthmatic effect, on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to the right.		Others
T1215	Nicardipine hydrochloride	RS-69216,Nicardipine HCl,YC-93 Hydrochloride	Calcium Channel , Adrenergic Receptor , AChR , Autophagy
	Nicardipine hydrochloride (YC-93 Hydrochloride) is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks cal...		Calcium Channel , Adrenergic Receptor , AChR , Autophagy
TP1198	Sincalide ammonium	SQ19844 ammonium,CCK-8 ammonium,Cholecystokinin octapeptide ammonium	cholecystokinin
	Sincalide ammonium (CCK-8 ammonium) is a potent analog of the amino acid peptide hormone cholecystokinin (CCK), an active fragment that retains much of the biological activity of CCK.Sincalide ammonium promotes bile secr...		cholecystokinin
T4739	Sodium creatine phosphate dibasic tetrahydrate	Creatine phosphate disodium salt tetrahydrate	Others , Endogenous Metabolite
	Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) mainly exists in the skeletal muscles of vertebrates. It is a substrate for the determination of creatine kinase and can be u...		Others , Endogenous Metabolite
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T5856	Barnidipine hydrochloride	YM-09730-5 hydrochloride,Mepirodipine (hydrochloride)	Calcium Channel
	Barnidipine hydrochloride (YM-09730-5 hydrochloride) is a dihydropyridine calcium channel blocker that has an IC50 value of 0.35 nM in potassium-induced tonic contraction of pig coronary artery		Calcium Channel