Search Result

Search Results for " erk1 "

Targets

134

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T11226	ERK1/2 inhibitor 1		ERK
	ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.		ERK
T8472	ERK1/2 inhibitor 2	ASTX-029,ASTX029	ERK
	ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.		ERK
T78190	ERK1/2 inhibitor 9		ERK
	ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 μM) and facilitates the reduction of phospho-ERK1/2 levels. When conjugated with trans-cy...		ERK
T64147	ERK1/2 inhibitor 6
	ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 6 has shown potential for the study or prevention of cancer, inflammation or other proliferative diseases.
T63331	ERK1/2 inhibitor 8
	ERK1/2 inhibitor 8 is a potent inhibitor of ERK that acts on ERK2 (IC50: 0.48 nM).
T64155	ERK1/2 inhibitor 5
	ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 5 has the potential to investigate or prevent cancer, inflammation or other proliferative diseases.
T62933	ERK1/2 inhibitor 7
	ERK1/2 inhibitor 7 is a potent inhibitor of ERK, acting on ERK2 (IC50: 0.94 nM).
T74373	ERK1/2 inhibitor 3
	ERK1/2 Inhibitor 3, a potent inhibitor of ERK1/2, plays a crucial role in the signal transduction pathway by targeting the Mitogen-activated protein kinase (MAPK) family, specifically the extracellular signal-regulated k...
T74374	ERK1/2 inhibitor 4
	ERK1/2 Inhibitor 5, a potent suppressant of the ERK1/2 pathway, is instrumental in the mitogen-activated protein kinase (MAPK) signal transduction pathway, where extracellular signal-regulated kinase (ERK) serves as a cr...
T64587	P44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R
	p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R is a useful organic compound for research related to life sciences and the catalog number is T64587.
T64608	Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R
	Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R is a useful organic compound for research related to life sciences and the catalog number is T64608.
TP1474	LXW7		Integrin
	LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti...		Integrin
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T6308	Stattic	STAT3 Inhibitor V	Apoptosis , STAT
	Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis.		Apoptosis , STAT
T7506	Yoda 1		Piezo Channel
	Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)		Piezo Channel
T8492	BO-264		Apoptosis , FGFR
	BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).		Apoptosis , FGFR
T23322	SB 452533		TRP/TRPV Channel
	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).		TRP/TRPV Channel
T3183	SAX-187	WAY 181187,WAY181187	5-HT Receptor
	SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.		5-HT Receptor
T9141	ERK-IN-3	ASN007 free base	ERK
	ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.		ERK
T6150	TAK-715		p38 MAPK , Casein Kinase , JNK
	TAK-715 is a p38 MAPK inhibitor for p38α.		p38 MAPK , Casein Kinase , JNK
T5097	Ezatiostat	TER199(free base),TLK199	Apoptosis , Glutathione Peroxidase , GST
	Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.		Apoptosis , Glutathione Peroxidase , GST
T4478	CID 16020046	C390-0219	Cannabinoid Receptor
	CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.		Cannabinoid Receptor
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T22776	Ezatiostat hydrochloride	TLK199 HCl,TER199	Glutathione Peroxidase
	Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr...		Glutathione Peroxidase
T6511	Ravoxertinib	GDC-0994	ERK
	Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).		ERK
T12069	MK-8353	SCH900353	ERK
	MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)		ERK
T1956	FR 180204	FR180204	Apoptosis , ERK
	FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.		Apoptosis , ERK
T6948	Pluripotin	SC1	ERK , Raf , S6 Kinase
	Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.		ERK , Raf , S6 Kinase
T6066	SCH772984		ERK , MEK
	SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.		ERK , MEK
T6218	Selumetinib	ARRY-142886,AZD6244	Apoptosis , ERK , MEK
	Selumetinib (AZD6244) (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).		Apoptosis , ERK , MEK
T6949	PLX7904	PB04	Raf
	PLX7904 (PB04), also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutan...		Raf
T41190	AY 77	Unk-Cha-Chg-NH2	ERK , Calcium Channel , Protease-activated Receptor
	AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM). AY 77 can p...		ERK , Calcium Channel , Protease-activated Receptor
TQ0005	KO-947		ERK
	KO-947 is a potent and specific inhibitor of ERK1/2 kinases.		ERK
T21980	PD 198306		MEK
	PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.		MEK
T22379L	NLX-204 hydrochloride（2170405-10-2 free base）		5-HT Receptor
	NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).		5-HT Receptor
T22996	ML-191		ERK
	ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.		ERK
TP1970L	Prosaptide TX14(A) acetate	Prosaptide TX14(A) acetate(196391-82-9 free base)	ERK , GPR
	Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.		ERK , GPR
T33452	ML192	ML-192,CID1434953,CID 1434953,ML 192,CID-1434953	Cannabinoid Receptor , GPR , Arrestin
	ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation.		Cannabinoid Receptor , GPR , Arrestin
T7005	Ulixertinib	BVD-523,VRT752271	ERK
	Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.		ERK
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T4091	Temuterkib	LY3214996	ERK
	Temuterkib (LY3214996) is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity.		ERK
T11224	Rineterkib	ERK-IN-1	ERK , Raf
	Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.		ERK , Raf
T6189	Mirdametinib	PD325901,PD0325901	Apoptosis , MEK , Autophagy
	Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis.		Apoptosis , MEK , Autophagy
T2156	WP1066		Apoptosis , JAK , STAT
	WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra...		Apoptosis , JAK , STAT
T4092	AG126	Tyrphostin AG126,AG 126	ERK , COX
	AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expres...		ERK , COX
T6440	CGP 57380	MNK1 Inhibitor	Apoptosis , MNK
	CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.		Apoptosis , MNK
T23396	ST1936	ST 1936 oxalate	5-HT Receptor
	ST1936 (ST 1936 oxalate) is a selective and potent 5-HT6 receptor agonist that inhibits human 5-HT6, 5-HT7, and 5-HT2B receptors, and stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases through the complete activation of the ...		5-HT Receptor
T62929	RLX-33		ERK , RXFP receptor
	RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation. RLX-33 can block the increase in food intake ...		ERK , RXFP receptor
T36674	DMU-212		Apoptosis , ERK
	DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...		Apoptosis , ERK

Compounds

Synonym: ASTX-029,ASTX029

p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb #4695R

T64587

Synonym:

Target:

Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb #4376R

Synonym: PHPS-1,PHPS 1

Target: Phosphatase

Stattic

T6308

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

Yoda 1

T7506

Synonym:

Target: Piezo Channel

BO-264

T8492

Synonym:

Target: Apoptosis, FGFR

SB 452533

T23322

Synonym:

Target: TRP/TRPV Channel

SAX-187

T3183

Synonym: WAY 181187,WAY181187

Target: 5-HT Receptor

ERK-IN-3

T9141

Synonym: ASN007 free base

Target: p38 MAPK, Casein Kinase, JNK

Ezatiostat

T5097

Synonym: TER199(free base),TLK199

Target: Apoptosis, Glutathione Peroxidase, GST

CID 16020046

T4478

Synonym: C390-0219

Target: Cannabinoid Receptor

Fasudil

T1606

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Ezatiostat hydrochloride

T22776

Synonym: TLK199 HCl,TER199

Target: Glutathione Peroxidase

Target: Apoptosis, ERK

Pluripotin

T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

Synonym: ARRY-142886,AZD6244

Target: Apoptosis, ERK, MEK

Synonym: Unk-Cha-Chg-NH2

Target: ERK, Calcium Channel, Protease-activated Receptor

NLX-204 hydrochloride（2170405-10-2 free base）

T22379L

Synonym:

Target: 5-HT Receptor

Prosaptide TX14(A) acetate

TP1970L

Synonym: Prosaptide TX14(A) acetate(196391-82-9 free base)

Target: ERK, GPR

ML192

T33452

Synonym: ML-192,CID1434953,CID 1434953,ML 192,CID-1434953

Target: Cannabinoid Receptor, GPR, Arrestin

Ulixertinib

T7005

Synonym: BVD-523,VRT752271

Synonym: PD325901,PD0325901

Target: Apoptosis, MEK, Autophagy

WP1066

T2156

Synonym:

Target: Apoptosis, JAK, STAT

AG126

T4092

Synonym: Tyrphostin AG126,AG 126

Target: ERK, COX

CGP 57380

T6440

Synonym: MNK1 Inhibitor

Target: Apoptosis, MNK

ST1936

T23396

Synonym: ST 1936 oxalate

Target: 5-HT Receptor

RLX-33

T62929

Synonym:

Target: ERK, RXFP receptor

DMU-212

T36674

Synonym:

Target: Apoptosis, ERK

Cat No.	Product Name	Synonyms	Targets
TN1493	Chrysosplenol D		IL Receptor , NF-κB , JNK
	Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.		IL Receptor , NF-κB , JNK
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
TN7108	Urolithin C		Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite
	Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
T3844	Deltonin		ERK , Others , Akt , Endogenous Metabolite
	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).		ERK , Others , Akt , Endogenous Metabolite
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
TL0016	Sulforaphene		Apoptosis , ERK , EGFR , NF-κB
	Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...		Apoptosis , ERK , EGFR , NF-κB
T6S1587	Notoginsenoside R2	20(S)-Notoginsenoside R2,Ginsenoside Ng-R2	Others , Nrf2
	Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways.		Others , Nrf2
T2S2382	3'-Hydroxypterostilbene	3'-HPT	Apoptosis , Autophagy
	3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b...		Apoptosis , Autophagy
TN4379	Kansuinine A		IL Receptor , STAT , Interleukin
	Kansuinine A possesses analgesic props, it also shows NGF inducing activity.		IL Receptor , STAT , Interleukin
TN1015	Meranzin		Adrenergic Receptor , Immunology/Inflammation related
	Meranzin, a bioactive compound derived from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS) and isolated from Murraya exotica L. leaves, targets the alpha 2-adrenoceptor and engages the AMPA-ERK1/2–BDNF si...		Adrenergic Receptor , Immunology/Inflammation related
T3857	Magnolin	(+)-Magnolin	ERK
	Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.		ERK
T5S2361	Epiberberine		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
	1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe...		ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE
TCS1704	Artemitin	Artemetin,Artemisetin,Erianthin	Antioxidant
	1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenou...		Antioxidant
T5S1058	Triptonide	PG 492,NSC 165677	Apoptosis , Wnt/beta-catenin , Autophagy
	1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an...		Apoptosis , Wnt/beta-catenin , Autophagy
TN1922	Meranzin hydrate		ERK , Adrenergic Receptor
	Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produ...		ERK , Adrenergic Receptor
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
T3S0013	Ethyl trans-caffeate	Ethyl caffeate,Caffeic Acid Ethyl Ester	Others
	1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a...		Others
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T3855	Tracheloside		Estrogen Receptor/ERR , Phosphorylase
	Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).		Estrogen Receptor/ERR , Phosphorylase
T5S0055	Chelidonine	Helidonine,Khelidonin,Stylophorin	Apoptosis , Others , Influenza Virus
	1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...		Apoptosis , Others , Influenza Virus
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
T4S2326	Cornuside	7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside	ERK , p38 MAPK , NF-κB , JNK
	1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...		ERK , p38 MAPK , NF-κB , JNK
T3S0209	Vincristine		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
	Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato...		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
T6S2099	Geraniin		Antioxidant , TNF
	1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...		Antioxidant , TNF
T6947	Piperlongumine	PPLGM,Piplartine	Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
T2698	Asperosaponin VI	Akebia saponin D,Asperosaponin Ⅵ	Apoptosis , Others , Caspase
	Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.		Apoptosis , Others , Caspase
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
T15542	Hypothemycin		Others
	Hypothemycin is a fungal polyketide and is a multikinase inhibitor (Kis: 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8.4/2.4 μM for VEGFR2/VEGFR1, MEK1/MEK2, FLT-3, PDGFRβ/PDGFRα, and ERK1/ERK2, respectively).		Others
TN3486	Bakkenolide IIIa		ERK , BCL , IκB/IKK , NF-κB , Akt
	Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-ÎºB signaling.		ERK , BCL , IκB/IKK , NF-κB , Akt
TN1211	2-Hydroxy-3-methylanthraquinone		ERK , p38 MAPK , Caspase
	2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.		ERK , p38 MAPK , Caspase
T16011	Manumycin A		Prostaglandin Receptor
	Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a ...		Prostaglandin Receptor
TN5100	Taspine		ERK , EGFR , BCL , VEGFR , MAPK , Akt
	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful an...		ERK , EGFR , BCL , VEGFR , MAPK , Akt
TN3655	Cimiside E		ERK , TNF , ROS , Akt , PI3K , PKC , PPAR
	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may b...		ERK , TNF , ROS , Akt , PI3K , PKC , PPAR
T27174	Dihydrocelastrol	DHCE. (-)-Triptohypol C,Triptohypol C
	Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through casp...
T75602	Albanol B
	Albanol B, an arylbenzofuran derivative, is extracted from mulberries and demonstrates multifarious biological activities, including anti-Alzheimer's, anti-bacterial, and antioxidant effects. It inhibits the proliferatio...
TN4168	Grifolin		Others
	Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proli...		Others
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...

Natural Products

Chrysosplenol D

TN1493

Synonym:

Target: IL Receptor, NF-κB, JNK

Epieriocalyxin A

TN3967

Synonym:

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Urolithin C

TN7108

Synonym:

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, IGF-1R, Endogenous Metabolite

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Theaflavin 3,3'-digallate

T5429

Synonym: 8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Mogrol

TN2346

Synonym:

Target: ERK, AMPK, STAT

Deltonin

T3844

Synonym:

Target: ERK, Others, Akt, Endogenous Metabolite

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Target: Apoptosis, ERK, EGFR, NF-κB

Notoginsenoside R2

T6S1587

Synonym: 20(S)-Notoginsenoside R2,Ginsenoside Ng-R2

Target: Others, Nrf2

3'-Hydroxypterostilbene

T2S2382

Synonym: 3'-HPT

Target: Apoptosis, Autophagy

Kansuinine A

TN4379

Synonym:

Target: IL Receptor, STAT, Interleukin

Meranzin

TN1015

Synonym:

Target: Adrenergic Receptor, Immunology/Inflammation related

magnolin

T3857

Synonym: (+)-Magnolin

Target: ERK, Beta-Secretase, MEK, BACE, AMPK, AChR, AChE

Artemitin

TCS1704

Synonym: Artemetin,Artemisetin,Erianthin

Target: Antioxidant

Triptonide

T5S1058

Synonym: PG 492,NSC 165677

Target: Apoptosis, Wnt/beta-catenin, Autophagy

Meranzin hydrate

TN1922

Synonym:

Target: ERK, Adrenergic Receptor

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Ethyl trans-caffeate

T3S0013

Synonym: Ethyl caffeate,Caffeic Acid Ethyl Ester

Target: ERK, p38 MAPK, NF-κB

Tracheloside

T3855

Synonym:

Target: Estrogen Receptor/ERR, Phosphorylase

Chelidonine

T5S0055

Synonym: Helidonine,Khelidonin,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: ERK, PDGFR

Cornuside

T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

Vincristine

T3S0209

Synonym:

Target: ERK, p38 MAPK, NF-κB, Akt, JNK, mTOR

Geraniin

T6S2099

Synonym:

Target: Antioxidant, TNF

Piperlongumine

T6947

Synonym: PPLGM,Piplartine

Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy

Asperosaponin VI

T2698

Synonym: Akebia saponin D,Asperosaponin Ⅵ

Target: Apoptosis, Others, Caspase

Cucurbitacin IIb

T4S1469

Synonym:

Target: Apoptosis, Others

Target: ERK, BCL, IκB/IKK, NF-κB, Akt

2-Hydroxy-3-methylanthraquinone

TN1211

Synonym:

Target: ERK, p38 MAPK, Caspase

Manumycin A

T16011

Synonym:

Target: Prostaglandin Receptor

Taspine

TN5100

Synonym:

Target: ERK, EGFR, BCL, VEGFR, MAPK, Akt

Cimiside E

TN3655

Synonym:

Target: ERK, TNF, ROS, Akt, PI3K, PKC, PPAR

Dihydrocelastrol

T27174

Synonym: DHCE. (-)-Triptohypol C,Triptohypol C

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-01084	TrkA Protein, Human, Recombinant (His)	Human	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPH-01347	FSHR Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
TMPH-01348	FSHR Protein, Human, Recombinant (His)	Human	HEK293
	G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
TMPH-02214	Tomoregulin-1 Protein, Human, Recombinant (His)	Human	HEK293
	May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
TMPH-02135	SPRED1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiati...
TMPH-01082	CMKLR1 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways in...
TMPH-03203	FGFb Protein, Rabbit, Recombinant (His & SUMO)	Rabbit	E. coli
	Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di...
TMPH-01559	IL-26 Protein, Human, Recombinant (His)	Human	Yeast
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPH-01560	IL-26 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPH-03265	CMKLR2 Protein, Rat, Recombinant (His)	Rat	in vitro E. coli expression system
	Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates...
TMPY-04544	MEK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/...
TMPJ-01378	Mp1 Protein, Human, Recombinant (His)	Human	E. coli
	Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding pro...
TMPY-04551	P38 delta/MAPK13 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	The p38 family of mitogen-activated protein kinases (MAPK) includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms tha...
TMPY-04531	P38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro	Human	Baculovirus-Insect Cells
	The p38 family of mitogen-activated protein kinases (MAPK) includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms tha...
TMPY-04539	ERK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPJ-00894	SCF Protein, Rat, Recombinant (His)	Rat	E. coli
	Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesi...
TMPK-00523	FLT3 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the re...
TMPK-00416	FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	CHO
	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the re...
TMPY-04571	ERK2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-05095	RAF1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct...
TMPH-01746	NOX4 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPJ-00996	VHR Protein, Human, Recombinant (His)	Human	E. coli
	Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues...
TMPY-02907	FGF-19 Protein, Human, Recombinant	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPH-01745	NOX4 Protein, Human, Recombinant (Cell-Free, His)	Human	in vitro E. coli expression system
	Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPY-05314	TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-00231	TGF beta 2 Protein, Canine, Recombinant (His)	Canine	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-04399	TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)	Human	Baculovirus-Insect Cells
	Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-i...
TMPY-04466	STK40 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to...
TMPH-00354	CSF1R Protein, Feline, Recombinant (His & SUMO)	Feline	E. coli
	Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially monon...
TMPY-00413	TGF beta 2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-04577	TGF beta 2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPH-01086	CSPG4 Protein, Human, Recombinant (His & Myc)	Human	HEK293
	Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon rege...
TMPH-01336	FGFR1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TMPH-01337	FGFR1 Protein, Human, Recombinant (Yeast, His)	Human	Yeast
	Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required...
TMPY-06527	TREM-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPH-00273	IGF1/IGF-I Protein, Bovine, Recombinant (hFc)	Bovine	Yeast
	The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose ...
TMPY-02519	BLVRB Protein, Human, Recombinant (His)	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann...
TMPY-00943	TREM-1 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-04357	RSK4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kina...
TMPY-04392	RSK3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a ...
TMPY-01759	TrkA Protein, Human, Recombinant (aa 285-413, His)	Human	E. coli
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03536	TrkA Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03712	TrkA Protein, Canine, Recombinant (His)	Canine	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPY-04663	TrkA Protein, Rabbit, Recombinant (His)	Rabbit	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-01083	TrkA Protein, Human, Recombinant (His & hFc)	Human	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
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