parg

Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

Endo-1,4-β-xylanase (Xylanase), a glycoside hydrolase enzyme that degrades arabinoxylan (AX), is commonly utilized in biochemical research. It specifically hydrolyzes the β-xylosidic bonds linking two d-xylopyranosyl residues in a β-(1,4) configuration [1].

COH34 analog 1 is a COH34 oxidation analogue that can be used to synthesize active compounds.

COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.

PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.

PARG-IN-4 (compound A) is an orally active and cell-membrane permeable PARG inhibitor (EC50=1.9 nM) that inhibits tumour growth in mice with antitumour activity.

O-Propargyl-Puromycin (OP-puro) is a potent protein synthesis inhibitor, a puromycin acetylene analog.

Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.

Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.

Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.

Propargyl-PEG3-amine (Propargyl-PEG3-NH2) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

L-Propargylglycine ((S)-Propargylglycine) is an inhibitor of the enzyme.

Clodinafop-propargyl is a post-emergence herbicide belonging to the propionic acid arylphenoxy (AOPP) class, inhibiting acetyl-CoA carboxylase (ACCase), and is used for annual grass weeds.

Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker and a PEG-based PROTAC linker, used to synthesize 6-OHDA-PEG3-yne, a compound containing 6-OHDA and Propargyl-PEG3-acid[1].

Propargyl-PEG12-bromide, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Propargyl-PEG11-methane is a PEG-based PROTAC linker utilized for the synthesis of PROTACs [1].

Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs.

Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs.

DL-Propargylglycine HCl (DL-Propargyl Glycine HCl) is a potent irreversible inhibitor of cystathionine γ-cleaving enzyme and can be used in the study of heart failure.

Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].

Pargolol hydrochloride is an antagonist of β adrenergic receptor.

Propargyl p-toluenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T124543 and the CAS number is 6165-76-0.

Propargyl benzenesulfonate is a useful organic compound for research related to life sciences. The catalog number is T124544 and the CAS number is 6165-75-9.

(S,R,S)-AHPC-propargyl, a VHL ligand, is utilized in click reactions for PROTACs.