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Hematologic Malignancies Target Proteins

In hematological malignancies, CD19, BCMA, and CD22 are the most frequently studied target proteins. CD19 is the primary target for the treatment of B-cell blood cancers. BCMA and CD22 are both antigens expressed on the surface of B cells, and cell therapies targeting these two targets could be used to treat patients with B-cell blood cancers that have developed resistance to cell therapies targeting CD19. Other related targets under study include GPRC5D, CLEC12A and CD7.

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Species
Canine (3)
Cynomolgus (21)
Ferret (2)
Human (111)
Mouse (36)
Rabbit (2)
Rat (13)
Rhesus (16)
Rhesus Macaque (2)
Rhesus macaque (4)
Source
Baculovirus-Insect Cells (5)
CHO (1)
E. coli (4)
HEK293 (165)
Human Cells (23)
Label
AVI (19)
C-6His (6)
C-6His-Avi (3)
C-6His-Flag (1)
C-Fc (7)
C-Flag (1)
C-His (9)
C-His-Avi (20)
C-hFc (4)
C-mFc (2)
FLAG (1)
Fc (2)
GST (1)
His (81)
N-6His (1)
N-6His-Flag (1)
N-Fc (1)
N-His-Avi (2)
N-hFc-Flag (2)
Tag Free (9)
TrxA (2)
hFc (43)
mFc (3)
rFc (1)
Cat No. product name / Synonyms Species Source
TMPJ-00066 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
Human Human Cells
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consis...
TMPJ-00097 NKG2D Protein, Cynomolgus, Recombinant (hFc)
NKG2D Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus Human Cells
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil...
TMPJ-00122 NKG2D Protein, Mouse, Recombinant (His)
NKG2D Protein, Mouse, Recombinant (His)
Mouse Human Cells
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil...
TMPJ-00148 FOLR1 Protein, Rhesus macaque, Recombinant (His)
FOLR1 Protein, Rhesus macaque, Recombinant (His)
Rhesus Macaque Human Cells
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lu...
TMPJ-00184 CD20 Protein, Human, Recombinant (Flag)
CD20 Protein, Human, Recombinant (Flag)
Human Human Cells
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ...
TMPJ-00185 CD20 Protein, Human, Recombinant (His & Flag)
CD20 Protein, Human, Recombinant (His & Flag)
Human Human Cells
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ...
TMPJ-00190 CD38 Protein, Mouse, Recombinant (hFc)
CD38 Protein, Mouse, Recombinant (hFc)
Mouse Human Cells
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It sy...
TMPJ-00221 SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
Human Human Cells
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ...
TMPJ-00222 SLAMF7 Protein, Human, Recombinant (mFc)
SLAMF7 Protein, Human, Recombinant (mFc)
Human Human Cells
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ...
TMPJ-00329 CD19 Protein, Rhesus macaque, Recombinant (hFc)
CD19 Protein, Rhesus macaque, Recombinant (hFc)
Rhesus macaque Human Cells
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B c...
TMPJ-00340 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
Human Human Cells
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
TMPJ-00341 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
Human Human Cells
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
TMPJ-00342 CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
Human Human Cells
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
TMPJ-00343 CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
Human Human Cells
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
TMPJ-00392 Siglec-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Siglec-2 Protein, Human, Recombinant (His & Avi), Biotinylated
Human Human Cells
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
TMPJ-00393 Siglec-2 Protein, Human, Recombinant (hFc)
Siglec-2 Protein, Human, Recombinant (hFc)
Human Human Cells
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
TMPJ-00444 Siglec-2 Protein, Mouse, Recombinant (His)
Siglec-2 Protein, Mouse, Recombinant (His)
Mouse Human Cells
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
TMPJ-00487 SDC1 Protein, Human, Recombinant (hFc)
SDC1 Protein, Human, Recombinant (hFc)
Human Human Cells
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt...
TMPJ-00488 SDC1 Protein, Human, Recombinant (His)
SDC1 Protein, Human, Recombinant (His)
Human Human Cells
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt...
TMPJ-01434 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus Human Cells
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one...
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)
TMPJ-00066
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consis...
NKG2D Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00097
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil...
NKG2D Protein, Mouse, Recombinant (His)
TMPJ-00122
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil...
FOLR1 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00148
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lu...
CD20 Protein, Human, Recombinant (Flag)
TMPJ-00184
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ...
CD20 Protein, Human, Recombinant (His & Flag)
TMPJ-00185
CD20 is a 33-37 kDa non-glycosylated protein expressed on the surface of normal and malignant B lymphocytes, and belongs to the MS4A (membrane-spanning 4-domain ...
CD38 Protein, Mouse, Recombinant (hFc)
TMPJ-00190
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It sy...
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00221
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ...
SLAMF7 Protein, Human, Recombinant (mFc)
TMPJ-00222
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, ...
CD19 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00329
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B c...
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His & Avi), Biotinylated
TMPJ-00340
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc)
TMPJ-00341
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His)
TMPJ-00342
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
TMPJ-00343
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody respon...
Siglec-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00392
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
Siglec-2 Protein, Human, Recombinant (hFc)
TMPJ-00393
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
Siglec-2 Protein, Mouse, Recombinant (His)
TMPJ-00444
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-typ...
SDC1 Protein, Human, Recombinant (hFc)
TMPJ-00487
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt...
SDC1 Protein, Human, Recombinant (His)
TMPJ-00488
Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cyt...
BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-01434
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one...
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TargetMol