vaccine

TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

KRAS G13D peptide, a 25-mer sequence, is derived from the KRAS activating oncogene mutation and serves as an immune potentiator. This peptide possesses immunogenic properties and can be utilized for the development of a KRAS vaccine.

Nelipepimut-S, as an immunogenic peptide from the HER2 protein, is highly expressed in breast cancer.

AADvac1 is a biologically active peptide functioning as an Alzheimer's Disease Peptide Vaccine, composed of Tau(294–305) conjugated to Keyhole Limpet Hemocyanin (KLH).

IRGRILHDGAYSLTLQGLGIH is a multi-epitope class II rat HER2 neu peptide used in HER2-DC1 vaccine research studies [1].

Onilcamotide, a cancer vaccine derived from the C-terminal peptide of the RhoC protein, exhibits potential immunomodulating and antineoplastic activities.

Enterotoxin STp (E. coli), a heat-stable enterotoxin, is applicable in vaccine research [1].

Autoinducing Peptide I, a cyclic octapeptide produced by Staphylococcus aureus, has applications in vaccine research [1].

Elpamotide is a vaccine consisting of a VEGFR2-169 peptide.

M2e, the human Transmembrane Domain of M2 Protein (TFA), encompasses the 23 extracellular residues of M2, the third integral membrane protein of Influenza A, and exhibits remarkable conservation across all strains of human influenza A. This conservation positions M2e, human TFA as a promising and adaptable vaccine candidate capable of providing protection against all strains of human influenza A [1].

The NPNA hexamer, a peptide, holds potential for malaria research and the development of a sporozoite vaccine [1].

SPPHPSPAFSPAFDNLYYWDQ TFA is a multi-epitope, class II rat HER2 neu peptide designed for research on the class II HER2-DC1 vaccine [1].

SPPHPSPAFSPAFDNLYYWDQ is a multi-epitope class II rat HER2 neu peptide used in the investigation of class II HER2-DC1 vaccine studies [1].

Tertomotide (GV1001) hydrochloride is a peptide vaccine composed of a 16-amino acid sequence from human telomerase reverse transcriptase (hTERT). It exhibits neuroprotective properties and has potential for research in Alzheimer's disease.

STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.

M2e, human, a vaccine candidate for human influenza A, encompasses the 23 extracellular residues of M2 (the third integral membrane protein of influenza A) and exhibits remarkable conservation across all strains, highlighting its potential as a broadly protective option.