sulfonamide

Chloroquinoxaline sulfonamide (Chloroquinoxaline) is a topoisomerase II alpha/beta toxin with antitumor activity and immunosuppressive properties that inhibits the proliferation of B16 melanoma cells in mice, and can be used to study metastatic colorectal cancer. It can be used to study metastatic colorectal cancer.

Phenylalanine-N-sulfonamide-CoA (Phenylalanine-N-sulfonamide-coenzyme A) is a derivative of coenzyme A.

Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.

Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.

Sulfaguanidine (Guanicil), a sulfonamide, is served as an anti-infective agent.

Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.

Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.

Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B).

E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).

N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Met inhibits endothelin binding to membranes from CHO cells carrying human ETA receptor and human ETB receptor with IC50 of 268nM and 1810nM, respectively.

TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.

4-(4,5-dibromo-6-oxo-1,6-dihydropyridazin-1-yl)benzene-1-sulfonamide is a sulfonamide derivative used in the synthesis of building blocks for various supramolecular structures such as metal-organic skeletons and coordination polymers. It has antiproliferative activity against a variety of tumor cell lines.

EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.

OBHSA(Oxabicycloheptane sulfonamide) is a novel selective estrogen receptor depressant (SERD) that can be used to study breast cancer.

GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.

W-9 hydrochloride is a calmodulin antagonist.

NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.

B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.

3-CHLORO-5-FLUORO-2-METHYLBENZENE SULFONAMIDE, with CAS No. 306937-31-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-CHLORO-5-FLUORO-2-METHYLBENZENE SULFONAMIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,5-dichloro-4-(difluoromethoxy)-N,N-dimethylbenzene-1-sulfonamide is a PDE inhibitor.

2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.

4-[(3-Methylphenyl)methoxy]benzene-1-sulfonamide ,with CAS No. 1097083-50-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-[(3-Methylphenyl)methoxy]benzene-1-sulfonamide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol (Compound 71) is a ligand designed for targeting proteins in PROTAC technology, featuring a sulfonamide linker that enhances the solubility of linker-conjugates. It is utilized in the synthesis of PROTACs with antitumor activity.