renin

Renin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is P00797-1.

Renin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.2 kDa and the accession number is P06281.

Renin Protein, Human, Recombinant (R66K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.74 kDa and the accession number is P00797-1.

Renin Protein, Macaca fascicularis, Recombinant (His) is expressed in E. coli. The accession number is Q6DLS0.

Expression system: E. coli
Length: 17-350, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 64-351, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-465, Full Length
Activity: Enzyme activity

Expression system: Baculovirus Insect Cells
Length: 1-464, Full Length
Activity: Enzyme activity

Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleave after a single arginine. It binds to a protein known as proSAAS, which also represents its endogenous inhibitor. PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. PCSK1 substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin. Defects in PCSK1 are the cause of proprotein convertase 1 deficiency (PC1 deficiency). PC1 deficiency is characterized by obesity, hypogonadism, hypoadrenalism, reactive hypoglycemia as well as marked small-intestinal absorptive dysfunction. It is due to impaired processing of prohormones.

Expression system: P. pastoris (Yeast)
Length: 391-638, Partial
Activity: Not Tested

Expression system: E. coli
Length: 391-638, Partial
Activity: Not Tested