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Anti-Renin Antibody (1I520)
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Catalog No. TMAB-12189
Anti-Renin Antibody (1I520) is a Mouse antibody targeting Renin. Anti-Renin Antibody (1I520) can be used in IHC-P,WB,IHC-Fr,IF.
Anti-Renin Antibody (1I520)
Anti-Renin Antibody (1I520)
😃Good
Catalog No. TMAB-12189
Anti-Renin Antibody (1I520) is a Mouse antibody targeting Renin. Anti-Renin Antibody (1I520) can be used in IHC-P,WB,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,059 | 7-10 days | 7-10 days | |
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Renin Antibody (1I520) is a Mouse antibody targeting Renin. Anti-Renin Antibody (1I520) can be used in IHC-P,WB,IHC-Fr,IF. |
| Clone | 1I520 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. Membrane. Associated to membranes via binding to ATP6AP2. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS (pH7.4). |
| Research Background | Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant Protein: human Renin protein |
| Antigen Species | Human |
| Gene Name | REN |
| Gene ID | |
| Protein Name | Renin |
| Uniprot ID | |
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Molecular Weight | Theoretical: 37 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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