helix — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1057	Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa	Phe-Met-Arg-Phe Like Peptide
	Phe-Met-Arg-Phe-like peptide, derived from the visceral and somatic muscles of the snail Helix aspersa, is a neuropeptide known as FMRF (Phe-Met-Arg-Phe). This peptide comprises four amino acid residues[1].
T80546	Thioether-cyclized helix B peptide, CHBP		mTOR
	Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy through the inhibition of mTOR C1 and activation of mTOR C2 [1].		mTOR
T80547	Thioether-cyclized helix B peptide, CHBP TFA		mTOR
	Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP. This form enhances metabolic stability and exhibits renoprotective effects by promoting autophagy, achieved through the inhibitio...		mTOR
T83756	S1H TFA	Site 1-binding Helix
	S1H, a synthetic peptide mimetic of human growth hormone amino acids 36-51, acts as an antagonist to the growth hormone receptor. It forms an α-helical structure in solution and inhibits STAT5 phosphorylation triggered b...
T81357	PTBP1 α3-helix derived peptide P1 TFA
	PTBP1α3-helix derived peptide P1 is a polypeptide that impedes RNA binding [1].
T81356	PTBP1-RNA-binding inhibitor P6 TFA	PTBP1 α3-helix derived peptide P6 TFA
	PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op...
T10860	Col003		HSP
	Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis.		HSP
T16670	PS210		PDK
	PS210 is a potent and selective activator of PDK1 (Kd: 3 μM), specifically targeting the PIF-binding pocket of PDK1, without acting against other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves ...		PDK
T3790	Hederacoside D		TNF
	Hederacoside D is a bioactive saponins from Hedera helix.		TNF
TP2311	C-MYC PEPTIDE EPITOPE TFA		Others
	C-MYC PEPTIDE EPITOPE TFA, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This pe...		Others
T21498	Phleomycin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T20511	6-Thioguanosine	6-Mercaptoguanosine,NSC29422,NSC 29422,NSC-29422	Others
	6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside, a metabolite of Azathioprine, and a low molecular weight gel.6-Thioguanosine is immunosuppressive and has been used to study the formation of the RNA double ...		Others
TP1057L	Phe-Met-Arg-Phe Like Peptide acetate	Pqdpflrfamide acetate,Phe-Met-Arg-Phe Like Peptide acetate（98495-35-3 free base)	Others
	Phe-Met-Arg-Phe Like Peptide acetate (Pqdpflrfamide acetate) is a FMRF-like peptide from visceral and somatic muscles of the snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino aci...		Others
T1779	SAG	Smoothened Agonist (SAG) HCl,Smoothened Agonist	Hedgehog/Smoothened , Smo
	SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.		Hedgehog/Smoothened , Smo
T6654	Saponins	Sapogenins Glycosides,Saponin	Others
	Saponins (Sapogenins Glycosides) are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effecti...		Others
T3345	Hederasaponin B	Eleutheroside M,Hederacoside B	Others , Virus Protease
	Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.		Others , Virus Protease
T14834	BT2		BCL
	BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, l...		BCL
T1006	Propantheline bromide	Neopepulsan,Pro-Banthine,Neometantyl	AChR
	Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...		AChR
TP2346	Peptide 399	(Leu-lys-lys-leu-leu-lys-leu)2
	Peptide 399 is an antimicrobial peptide with an idealized amphiphilic alpha helix.
T28133	NB-64
	NB-64 is a HIV-1 entry inhibitor. NB-64 interferes the gp41 six-helix bundle formation and blocks virus fusion.