TN1091 |
Dehydronuciferine
|
|
AChE
|
|
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylch... |
TN1011 |
Rhodionin
|
|
AChE
,
P450
|
|
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implica... |
T3852 |
Rhodiosin
|
|
Antioxidant
,
AChE
|
|
Rhodiosin is a compound with antioxidant activity. |
T13301 |
Violanthin
|
|
AChE
|
|
Violanthin is a natural product isolated from the aerial parts of Piper bavinum and inhibits acetylcholinesterase (AChE)... |
T2846 |
Isoimperatorin
|
|
AChE
,
Antibacterial
|
|
Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE). |
TN1858 |
Leptomerine
|
|
AChE
|
|
Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity. |
T5855 |
Edrophonium chloride
|
|
AChE
|
|
Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotran... |
TN1589 |
Dihydrowithaferin A
|
|
AChE
|
|
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE).... |
T5S1408 |
Pteryxin
|
(+)-Pteryxin |
Others
,
AChE
|
|
(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity. |
T5S2361 |
Epiberberine
|
|
BACE
,
MEK
,
ERK
,
AMPK
,
Beta-Secretase
,
AChR
,
AChE
|
|
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is me... |
T13469 |
(±)-Huperzine A
|
|
AChE
|
|
(±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs. (±)-Huperzine A is a selectiv... |
T7891 |
Ipidacrine
|
NIK‐247 |
Others
|
|
Ipidacrine (NIK‐247) is an Antidementia Agent |
TN1786 |
Isomerazin
|
Isomeranzin |
AChE
,
ERK
,
NF-κB
|
|
Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through ... |
T4S1725 |
Galanthamine
|
Galantamine |
AChE
,
Apoptosis
|
|
Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ische... |
T19084 |
1-Naphthyl acetate
|
|
AChE
|
|
1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a... |
T13681 |
Epi-galantamine
|
|
AChE
|
|
Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-gala... |
TN1899 |
Lycoramine
|
|
AChE
|
|
Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibi... |
T3769 |
Tenuifolin
|
|
Beta-Secretase
,
AChE
,
Others
|
|
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inh... |
T7114 |
GALANTHAMINONE
|
Narwedin,(-)-Narwedine |
AChE
|
|
Galanthaminone is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer's disease a... |
T11366 |
Garcinol
|
|
Endogenous Metabolite
,
AChR
,
AChE
,
Histone Acetyltransferase
,
Apoptosis
|
|
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM).... |