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Kinesin

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments, and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport.
Cat. No. Product name CAS No. Purity Chemical Structure
T16152 Betamethasone 17-benzoate 22298-29-9 98%
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
TQ0314 EMD534085 858668-07-2 98%
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
T9207 GW406108X 1644443-92-4 98%
GW108X is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW837331X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block aut...
T14906 CCT251455 1400284-80-1 98%
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T28848 SR31527 311814-78-5 98%
SR31527 is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability and colony formatio...
T11859L Litronesib 910634-41-2 98%
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T12434 PF-2771 2070009-55-9 98%
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
T4649 Monastrol 254753-54-3 98%
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T17007 TC-Mps1-12 1206170-62-8 98%
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
T9682 AZD-4877 758722-49-5 98%
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, ind...
T16130 Mps1-IN-3 1609584-72-6 98%
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
T14765 BOS-172722 1578245-44-9 98%
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
T9207L GW406108X(Z/E) 265098-01-9 98%
GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .
T2039 GSK-923295 1088965-37-0 98%
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
T12359 Paprotrain 57046-73-8 98%
Paprotrain is a cell-permeable the kinesin MKLP-2 inhibitor(inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM )
T2103 Ispinesib 336113-53-2 98%
Ispinesib, a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
T3120 K858 (Racemic) 72926-24-0 98%
K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
T2313 MPI-0479605 1246529-32-7 98%
MPI-0479605 is an ATP competitive and selective inhibitor.
T4048 Monastrol 329689-23-8 98%
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T6209 CW-069 1594094-64-0 98%
CW069( IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
Betamethasone 17-benzoate
T16152
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
EMD534085
TQ0314
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
GW406108X
T9207
GW108X is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW837331X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block aut...
CCT251455
T14906
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
SR31527
T28848
SR31527 is a potent KIFC1 inhibitor with an IC50 of 6.6 µM against KIFC1. SR31527 chloride has a moderate inhibitory effect on cell viability and colony formatio...
Litronesib
T11859L
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
PF-2771
T12434
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor activity with an IC 50 of 16.1 nM. PF-2771 is used as an...
Monastrol
T4649
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
TC-Mps1-12
T17007
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
AZD-4877
T9682
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, ind...
Mps1-IN-3
T16130
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
BOS-172722
T14765
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
GW406108X(Z/E)
T9207L
GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .
GSK-923295
T2039
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
Paprotrain
T12359
Paprotrain is a cell-permeable the kinesin MKLP-2 inhibitor(inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM )
Ispinesib
T2103
Ispinesib, a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
K858 (Racemic)
T3120
K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
MPI-0479605
T2313
MPI-0479605 is an ATP competitive and selective inhibitor.
Monastrol
T4048
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
CW-069
T6209
CW069( IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
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