Search Result

Search Results for " ribosome "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T8645	PF-06446846		Others
	PF 06446846 is a potent and selective PCSK9 inhibitor		Others
T4267	Tulathromycin A	CP 472295,Draxxin,Tulathromycin	Antibacterial , Antibiotic
	Tulathromycin A (CP 472295) is a macrolide antibiotic.		Antibacterial , Antibiotic
T19459	N1-Methylpseudouridine	1-Methylpseudouridine	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.		Others
T0788L	Spectinomycin dihydrochloride pentahydrate	Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome , Antibacterial , Antibiotic
	Spectinomycin dihydrochloride pentahydrate (Spectogard) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.		ribosome , Antibacterial , Antibiotic
T28506	Rbin-2		Phosphatase
	Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study...		Phosphatase
T7411	Rbin-1	Ribozinoindole-1	ATPase , Phosphatase
	Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.		ATPase , Phosphatase
T13767	MBX-4132		Others , Antibacterial
	MBX-4132, inhibit trans translation by binding to the bacterial ribosome,is a member of a chemical class called oxadiazoles.		Others , Antibacterial
T4222	KKL-10	KKL 10	ribosome , Antibacterial
	KKL-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria.		ribosome , Antibacterial
T1557	Acetylspiramycin	Spiramycin II,Foromacidin B,ASPM,Spiramycin B	ribosome , Antibacterial , Antibiotic
	Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.		ribosome , Antibacterial , Antibiotic
T3265	Azathramycin	Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin	Antibacterial , Antibiotic
	Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.		Antibacterial , Antibiotic
T1747	Tedizolid	TR 700,DA-7157,Torezolid	MAO , Antibacterial , Antibiotic
	Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.		MAO , Antibacterial , Antibiotic
T3052	Sancycline	Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline	Antibacterial
	Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.		Antibacterial
T1569	Tigecycline	GAR-936	ribosome , Antibacterial , Antibiotic , Autophagy
	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...		ribosome , Antibacterial , Antibiotic , Autophagy
T5189	Omadacycline	PTK 0796,Amadacycline	ribosome , Antibacterial , Antibiotic
	Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome.		ribosome , Antibacterial , Antibiotic
T6638	Retapamulin	SB-275833	ribosome , Antibacterial , Antibiotic
	Retapamulin (SB-275833), a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).		ribosome , Antibacterial , Antibiotic
T2331	Solithromycin	OP-1068,CEM-101	Antibacterial , Antibiotic
	Solithromycin (OP-1068) is an orally bioavailable antimicrobial agent that inhibits cell viability, protein synthesis, and growth rate of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus aureus, and Haemop...		Antibacterial , Antibiotic
T11836	Lefamulin acetate	BC-3781 acetate	ribosome , Antibacterial , Antibiotic
	Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acet...		ribosome , Antibacterial , Antibiotic
T22774L	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
T22707	Dalfopristin (mesylate) (112362-50-2 free base)	Dalfopristin (mesylate)	Others
	Dalfopristin (mesylate) is a streptogramin antibiotic and a 50S ribosome inhibitor. Streptogramins are produced by a variety of Streptomyces sp as a mixture (ratio of 7:3) of two chemically unrelated compounds, type A an...		Others
T71810	Thiamphenicol palmitate
	Thiamphenicol palmitate is a Prodrug of Thiamphenicol, inhibiting the 50S subunit of the bacterial ribosome and protein translation.
T18327	MC-Val-Cit-PAB-Retapamulin		Others
	MC-Val-Cit-PAB-Retapamulin is a drug-linker conjugate for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. This compound utilizes Retapamulin, a ribosome inhibitor, connected through the ADC linker...		Others
T27165	Diazaborine	Diazaborine compound 2b18,Pkf 84.474,Pkf 84474,Pkf-84474,SA-84474
	Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of ...
T70076	NOSO-95C
	NOSO-95C is an antibacterial compound that bind to the bacterial ribosome and kill bacteria through inhibition of the translation. NOSO-95C showed promising in vitro and in vivo efficacy against Enterobacteriaceae.
T19306	ELX-02 disulfate	NB-124 disulfate	Others
	ELX-02 disulfate (also referred to as NB-124 disulfate) is a synthetic eukaryotic ribosome selective glycoside (ERSG). This compound is currently in development as a therapy specifically designed to address genetic disea...		Others
T70323	Diethanolamine Fusidate
	Diethanolamine Fusidate is a bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid. This product inhibits protein synthesis in p...
T19307	ELX-02 sulfate	NB-124 sulfate	Others
	ELX-02 sulfate, also known as NB-124 sulfate, is a novel compound currently under development as a therapeutic agent for genetic diseases triggered by nonsense mutations. This investigational compound, an advanced synthe...		Others
T70250	Demeclocycline calcium
	Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tR...
T60300	BPH-1086
	BPH-1086 (compound 10) is an inhibitor of IspH. IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome [1] [2].
T9427	Selenocysteine		Others
	Selenocysteine is recognized as the 21st amino acid in ribosome-mediated protein synthesis and its specific incorporation is directed by the UGA codon.		Others
T38186	6-Amino-8-trifluoromethylphenanthridine
	6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM. 6A-8...
T34191	Pulchellin	NSC 85244
	Pulchellin is a type-2 Ribosome Inactivating Protein (RIP), whose action mechanism proposed would be initiate by B-chain binding on glycoconjugate onto the cell surface (lectinic chain). pulchellin isoforms toxicity is t...
TP2247	Eukaryotic translation initiation factor 3		Others
	Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i...		Others
T38613	Tigecycline hydrate	GAR-936 hydrate
	Tigecycline hydrate (GAR-936 hydrate) is a broad spectrum glycylcycline antibiotic. Tigecycline hydrate is bacteriostatic, that inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria and thereby b...
T40419	IRES-C11	IRES-C11	c-Myc
	IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans...		c-Myc
T36706	Bottromycin A2
	Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isola...
T75318	Spectinomycin
	Spectinomycin, a broad-spectrum antibiotic, targets and inhibits the growth of various gram-positive and gram-negative organisms by selectively binding to the bacterial ribosome, disrupting protein synthesis. Additionall...
T79759	Antifungal agent 74
	Antifungal agent 74 (compound 3c), is a potent substance that exhibits excellent fungicidal activity against C. arachidicola and R. solani, functioning by disrupting steroid biosynthesis and ribosome biogenesis in eukary...
T79015	SEQ-9
	SEQ-9 is an orally active inhibitor targeting the Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome, demonstrating an inhibitory concentration (IC50) around 170 nM against unmethylated Mtb ribosomes and showing pot...
T80402	Api137
	Api137 is an antimicrobial peptide that disrupts bacterial growth by blocking translation processes. Specifically, it inhibits protein synthesis through the entrapment of release factors on the 70S ribosome after the hyd...
T22774	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T4543	Telithromycin	HMR3647,Ketek,RU66647	Antibacterial , Antibiotic
	Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis...		Antibacterial , Antibiotic
T78055	MYC-RIBOTAC		c-Myc
	MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. Th...		c-Myc
T74144	Zifanocycline
	Zifanocycline (KBP-7072), a third-generation semisynthetic aminomethylcycline antibiotic, inhibits bacterial ribosome function, displaying broad-spectrum antibacterial activity in vitro against both Gram-positive and Gra...
T38187	6-Aminophenanthridine
	6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor a...
T83714	LAP TFA	Lupus Autoantigen Peptide,La Peptide
	Lupus autoantigen peptide (LAP), a derivative of the autoantigen La found in systemic lupus erythematosus (SLE) patients, spans amino acids 11-28 of La and functions as an antiviral peptide. It primarily blocks the hepat...
T81272	RIOK2-IN-1
	RIOK2-IN-1 (com 4) is a selective RIOK2 inhibitor with a Kd of 150 nM, though it demonstrates low cellular activity with an IC50 of 14,600 nM. As an atypical kinase, RIOK2's involvement in ribosome maturation and cell cy...

Compounds

Synonym: CP 472295,Draxxin,Tulathromycin

Target: Antibacterial, Antibiotic

N1-Methylpseudouridine

T19459

Synonym: 1-Methylpseudouridine

Target: Others

Spectinomycin dihydrochloride pentahydrate

T0788L

Synonym: Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

Synonym: Ribozinoindole-1

Target: ATPase, Phosphatase

MBX-4132

T13767

Synonym:

Target: Others, Antibacterial

KKL-10

T4222

Synonym: KKL 10

Target: ribosome, Antibacterial

Acetylspiramycin

T1557

Synonym: Spiramycin II,Foromacidin B,ASPM,Spiramycin B

Target: ribosome, Antibacterial, Antibiotic

Azathramycin

T3265

Synonym: Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin

Target: Antibacterial, Antibiotic

Tedizolid

T1747

Synonym: TR 700,DA-7157,Torezolid

Target: MAO, Antibacterial, Antibiotic

Sancycline

T3052

Synonym: Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline

Target: Antibacterial

Tigecycline

T1569

Synonym: GAR-936

Target: ribosome, Antibacterial, Antibiotic, Autophagy

Omadacycline

T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Retapamulin

T6638

Synonym: SB-275833

Target: ribosome, Antibacterial, Antibiotic

Solithromycin

T2331

Synonym: OP-1068,CEM-101

Target: Antibacterial, Antibiotic

Lefamulin acetate

T11836

Synonym: BC-3781 acetate

Target: ribosome, Antibacterial, Antibiotic

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

T22774L

Synonym:

Target: Others

Dalfopristin (mesylate) (112362-50-2 free base)

T22707

Synonym: Dalfopristin (mesylate)

Target: Others

Thiamphenicol palmitate

T71810

Synonym:

Target:

MC-Val-Cit-PAB-Retapamulin

Synonym: Diazaborine compound 2b18,Pkf 84.474,Pkf 84474,Pkf-84474,SA-84474

Synonym: NB-124 disulfate

Target: Others

Diethanolamine Fusidate

Synonym: NB-124 sulfate

Target: Others

Demeclocycline calcium

6-Amino-8-trifluoromethylphenanthridine

eukaryotic translation initiation factor 3

Synonym: GAR-936 hydrate

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Synonym: HMR3647,Ketek,RU66647

Target: Antibacterial, Antibiotic

6-Aminophenanthridine

Synonym: Lupus Autoantigen Peptide,La Peptide

Cat No.	Product Name	Synonyms	Targets
T1160	Fusidic acid	Fusidine	Others , CAT , Antibacterial , Antibiotic
	Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.		Others , CAT , Antibacterial , Antibiotic
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T12540	Pristinamycin IA	Mikamycin IA,Mikamycin B	Others , Antibiotic , P-gp
	Pristinamycin IA (Mikamycin B) is a substrate for the P-glycoprotein and a cyclo-peptidic macrolactone antibiotic.		Others , Antibiotic , P-gp
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T0788	Spectinomycin dihydrochloride	Spectinomycin 2HCl,Actinospectacin	ribosome , Antibacterial , Antibiotic
	Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.		ribosome , Antibacterial , Antibiotic
T1289	Fusidic acid sodium salt	Sodium fusidate,Fusidate Sodium,Fucidin,SQ-16360	Others , CAT , Antibacterial , Antibiotic
	Fusidic acid sodium salt (SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.		Others , CAT , Antibacterial , Antibiotic
T7148	JOSAMYCIN	EN-141	Antibacterial , Antibiotic
	Josamycin (EN-141) is a macrolide antibiotic exhibiting antimicrobial activity. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM.		Antibacterial , Antibiotic
T1214	Ribostamycin sulfate	Vistamycin sulfate	Antibacterial , Antibiotic
	Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.		Antibacterial , Antibiotic
T6758	Anisomycin	Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
	Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T6447	Clindamycin	Clinimycin,Sobelin,Chlolincocin	Antibacterial , Antibiotic
	Clindamycin (Sobelin) dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of t...		Antibacterial , Antibiotic
T5055	For-Met-OH	fMet,N-Formyl-L-methionine	Others , Endogenous Metabolite
	For-Met-OH (N-Formyl-L-methionine) is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and other ...		Others , Endogenous Metabolite
T64911	Blasticidin S HCl		Antibiotic
	Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide...		Antibiotic
T21430	Oxytetracycline Hydrochloride	Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin	Antiviral , Endogenous Metabolite , Antibacterial , HSV
	Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin...		Antiviral , Endogenous Metabolite , Antibacterial , HSV
T1022	Hygromycin B	Hygrovetine	ribosome , Antibacterial , Antibiotic , Antifungal
	Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic ...		ribosome , Antibacterial , Antibiotic , Antifungal
T0912	Tetracycline hydrochloride	NCI-c55561,Tetracycline HCl	ribosome , Antibacterial , Antibiotic
	Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ...		ribosome , Antibacterial , Antibiotic
T11842	Levomecol		Others
	Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthe...		Others

Natural Products

Fusidic acid

T1160

Synonym: Fusidine

Target: Others, CAT, Antibacterial, Antibiotic

Pseudouridine

T16674

Synonym:

Target: Endogenous Metabolite

Pristinamycin IA

T12540

Synonym: Mikamycin IA,Mikamycin B

Target: Others, Antibiotic, P-gp

Toyocamycin

T17143

Synonym: Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Spectinomycin dihydrochloride

T0788

Synonym: Spectinomycin 2HCl,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

Fusidic acid sodium salt

T1289

Synonym: Sodium fusidate,Fusidate Sodium,Fucidin,SQ-16360

Target: Others, CAT, Antibacterial, Antibiotic

JOSAMYCIN

T7148

Synonym: EN-141

Target: Antibacterial, Antibiotic

Ribostamycin sulfate

T1214

Synonym: Vistamycin sulfate

Target: Antibacterial, Antibiotic

Anisomycin

T6758

Synonym: Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Clindamycin

T6447

Synonym: Clinimycin,Sobelin,Chlolincocin

Target: Antibacterial, Antibiotic

For-Met-OH

T5055

Synonym: fMet,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

Oxytetracycline Hydrochloride

T21430

Synonym: Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin

Target: Antiviral, Endogenous Metabolite, Antibacterial, HSV

Hygromycin B

T1022

Synonym: Hygrovetine

Target: ribosome, Antibacterial, Antibiotic, Antifungal

Tetracycline hydrochloride

T0912

Synonym: NCI-c55561,Tetracycline HCl

Target: ribosome, Antibacterial, Antibiotic

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03751	C1orf33/MRTO4 Protein, Human, Recombinant (His)	Human	E. coli
	MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence si...
TMPJ-01395	NIP7 Protein, Human, Recombinant (His)	Human	E. coli
	60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a mo...
TMPH-03645	Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His)	Trichosanthes kirilowii	E. coli
	Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) is expressed in E. coli.
TMPH-02999	UL2 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase acti...
TMPH-01286	EEF2 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form...
TMPH-00558	30S ribosomal protein S11 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
TMPY-04073	MRPL44 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPH-00053	50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc)	Anaplasma phagocytophilum	E. coli
	This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with differen...
TMPH-01856	Pescadillo homolog Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
TMPH-02401	RplL Protein, Legionella pneumophila, Recombinant (His & Myc)	Legionella pneumophila	E. coli
	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
TMPH-02815	Nucleophosmin Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome ...
TMPH-01864	PITHD1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome...
TMPY-03184	EIF5 Protein, Human, Recombinant (GST)	Human	E. coli
	EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat...
TMPH-00559	30S ribosomal protein S15 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Binds to its own mR...
TMPH-01313	EIF4G1 Protein, Human, Recombinant (His)	Human	Yeast
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-03565	MazF Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f...
TMPH-03582	MazF Protein, S. epidermidis, Recombinant (His)	Staphylococcus epidermidis	E. coli
	Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f...
TMPY-03608	EEF1B2 Protein, Human, Recombinant (His)	Human	E. coli
	EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the...
TMPY-04108	EIF5A Protein, Human, Recombinant (His)	Human	E. coli
	EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat...
TMPH-01285	EEF1D Protein, Human, Recombinant (His)	Human	E. coli
	EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive g...
TMPH-01312	EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)	Human	E. coli
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01306	EIF4A1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str...
TMPY-03572	PTRH2 Protein, Human, Recombinant (His)	Human	E. coli
	PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic...
TMPJ-01396	PIN4 Protein, Human, Recombinant (His)	Human	E. coli
	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PA...
TMPH-01800	Nucleolin Protein, Human, Recombinant (His)	Human	Yeast
	Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is ...
TMPJ-00973	EIF1AX Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S...
TMPH-00561	30S ribosomal protein S4 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; With S5 and S12 plays an important role in translational accuracy; ma...
TMPJ-00507	EIF4E Protein, Human, Recombinant	Human	E. coli
	Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPH-01884	PCBP2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signali...
TMPH-00744	CsrA Protein, E. coli, Recombinant	E. coli	E. coli
	A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress...
TMPH-00756	Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc)	Escherichia phage MS2	E. coli
	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through ...
TMPH-00579	Antitoxin RelB Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Antitoxin component of a type II toxin-antitoxin (TA) system. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction, preventing RelE from entering the ribosome A site and thus inhibiting its...
TMPY-03343	EIF3K Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-...
TMPY-02844	EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-riboso...
TMPJ-01331	Frizzled-8 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep...
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-03288	EIF3I Protein, Rat, Recombinant (His)	Rat	Baculovirus
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPJ-01332	Frizzled-8 Protein, Human, Recombinant (His)	Human	Human Cells
	Frizzled-8 is one of at least ten seven-transmembrane (7TM) glycoproteins of the Frizzled family of Wnt receptors. Frizzled proteins are thought to be G-protein-coupled. Wnt engagement, with low density lipoprotein recep...
TMPH-01309	EIF3F Protein, Human, Recombinant (His)	Human	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPY-04259	Nucleophosmin Protein, Human, Recombinant (aa 2-294, His)	Human	E. coli
	Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly an...
TMPY-01925	Nucleophosmin Protein, Human, Recombinant (His)	Human	E. coli
	Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly an...
TMPH-01885	PABPC1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Binds the poly(A) tail of mRNA, including that of its own transcript, and regulates processes of mRNA metabolism such as pre-mRNA splicing and mRNA stability. Its function in translational initiation regulation can eithe...
TMPH-01310	EIF3G Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and ...
TMPH-01311	EIF3M Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-02315	XRCC5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-02314	XRCC5 Protein, Human, Recombinant (His & MBP)	Human	Baculovirus
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-00617	MazF Protein, E. coli, Recombinant (His)	E. coli	Yeast
	Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific endoribonuclease it inhibits protein synthesis by cleaving mRNA and inducing bacterial stasis. It is stable, single-strand specific with mRNA ...
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, an...