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pp3

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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Okadaic acid
T1638178111-17-8
Okadaic acid is a potent polyether marine toxin that accumulates in the digestive glands of marine mollusks.Okadaic acid is a highly potent and selective protein phosphatase (PP) inhibitor, inhibiting PP1, PP2A, PP3, PP4, and PP5.Okadaic acid activates Wnt β-catenin signaling in human HepaRG cells. catenin signaling in human HepaRG cells.
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PP 3
T231765334-30-5
PP 3 is a Negative control for the Src kinase inhibitor PP 2
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ENPP3 Inhibitor 1
T2032082803505-90-8
ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, exhibiting an IC50 value of 0.15 µM, compared to an IC50 of 41.4 µM for ENPP1. It demonstrates antitumor effects against breast and cervical cancers.
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PP30
PP 30,PP-30
T284391092788-09-4
PP30 is an inhibitor of mTORC1 and mTORC2. It is selective within the PI3K family, inhibiting other PI3Ks only at high concentrations.
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6-8 weeks
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ANAPP3
T6905358775-41-0
ANAPP3 is a P2x-purinoceptor antagonist. It affects contractions in various muscle groups and tissues.
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6-8 weeks
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Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody)
AGS-16C
T9901A-599
Anti-ENPP3 CD203c Antibody (AGS-16C3F antibody) is a human-derived antibody expressed in CHO cells, targeting ENPP3 CD203c. It features a huIgG1 heavy chain and a huκ light chain with an estimated molecular weight (MW) of 154.04 kDa. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
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2-4 weeks
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Okadaic acid ammonium salt
T39183175522-42-6
Okadaic acid ammonium salt, a marine toxin, serves as an inhibitor of protein phosphatases (PP), displaying a higher affinity for PP2A (IC50 = 0.1-0.3 nM) alongside inhibitory effects on PP1 (IC50 = 15-50 nM), PP3 (IC50 = 3.7-4 nM), PP4 (IC50 = 0.1 nM), and PP5 (IC50 = 3.5 nM), but does not affect PP2C. By inhibiting PPs, this compound promotes protein phosphorylation, acts as a tumor promoter, and is involved in inducing tau phosphorylation.
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