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Results for "

non-steroidal

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    193
    TargetMol | Inhibitors_Agonists
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    3
    TargetMol | Compound_Libraries
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Tolmetin
Tolectin
T255026171-23-3
Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.
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Finerenone
BAY94-8862, BAY-94-8862, BAY-948862, BAY948862, BAY 94-8862, BAY 948862
T213951050477-31-0
Finerenone (BAY-948862) is a nonsteroidal antagonist of the mineralocorticoid receptor (MR) (IC50=18 nM) with selective and oral activity. Finerenone is used in the treatment of patients with chronic kidney disease with type 2 diabetes.
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Vedaprofen
Quadrisol, PM 150, CERM 10202
T3668371109-09-6In house
Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.
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Giredestrant tartrate
Estrogen receptor antagonist 1
T112362407529-33-1In house
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
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8-10weeks
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Furprofen
T1134066318-17-0In house
Furprofen is a non-steroidal anti-inflammatory agent that inhibits prostate (PGE) synthesis and is used in the study of rheumatoid arthritis and osteoarthritis.
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7-10 days
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Pirazolac
MY309, MY-309, SCH 376, ZK-76604, SCH376, ZK76604
T1248471002-09-0In house
Pirazolac (ZK-76604) is a novel non-steroidal anti-inflammatory agent for the study of rheumatoid arthritis.
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Sulindac sulfide
cis-Sulindac sulfide
T1303749627-27-2In house
Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 μM. It is an active metabolite of sulinic acid.
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4-6weeks
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Bermoprofen
AJ-1590, AD-1590
T1454678499-27-1In house
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with analgesic properties, utilized in gastric ulcer studies.
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Epristeride
SKF105657, ONO-9302
T15239119169-78-7In house
Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.
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6-8 weeks
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G36
G-36
T227941392487-51-2In house
G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17β-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). G36 has no detectable binding activity to either ERα or ERβ. G36 blocks the activation of PI3K or calcium mobilization triggered by estrogen through GPER and it suppresses ERK activation by estrogen or G-1 but not by EGF. G-36 can be used in combination with GPER-selective agonists, like G-1, to distinguish the roles of GPER from those of ERα and ERβ in complex biological systems.
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6-8weeks
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Prifelone
R-830, R830, S-16820, S 16820, R 830
T2598569425-13-4In house
Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.
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(-)-Vorozole
(-)-Vorozole(Isomer-129731-10-8)
T26322L132042-69-4In house
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo experiments. (-)-Vorozole is used in the study of breast cancer.
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Butibufen
FF-106, FF106, FF 106, FF 105
T2692655837-18-8In house
Butibufen (FF-106) is an orally active non-steroidal anti-inflammatory compound, a potential cyclooxygenase inhibitor with analgesic and antipyretic activity, and inhibits urea synthesis.Butibufen has been used in the study of rheumatic diseases.
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6-8 weeks
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Droxicam
Droxicamum
T2720990101-16-9In house
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders.
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6-8 weeks
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Eltenac
BY-820, BY820, BY 820, B-78820, B78820, B 78820
T2725472895-88-6In house
Eltenac (B78820) is a non-steroidal anti-inflammatory, COX inhibitor with analgesic activity.Eltenac inhibits COX-1 and COX-2 and is used in the study of Acute Respiratory Distress Syndrome (ARDS).
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6-8 weeks
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EN3356
AS N001, ASN-001
T301611429329-63-4In house
EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage enzyme-selective compound with potential anti-androgenic and anti-tumor activity.
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Zoliprofen
T6802556355-17-0In house
Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat paw oedema, as well as anti-rat serum-induced fracture or dorsal skin oedema. Zoliprofen is 20 times more effective than ibuprofen and fenoprofen against collagen- or arachidonic acid-induced platelet aggregation in rats and rabbits. Zoliprofen was 20 times more effective than ibuprofen and fenoprofen in inhibiting endotoxin-induced diarrhoea in mice and arachidonic acid-induced acute mortality in rabbits.
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Delmetacin
Demethacin
T6805216401-80-2In house
Delmetacin (Demethacin) is a non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity and inhibitory effects on the CXC chemokine receptor CXCR1.
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Tebufelone
T68155112018-00-5In house
Tebufelone is a potent in vitro inhibitor of CO , a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has shown potent anti-inflammatory, analgesic and anti-reticulitis properties in various animal models. Tebufelone potently inhibits the formation of prostaglandins (PGE2) and blocks the formation of lipoxygenase pathway products [leukotriene (LTB4)] in rat macrophages (IC50 = 20 microM) and human whole blood (IC50 = 22 microM) in vitro. = 20 microM) and human whole blood (IC50 = 22 microM) from the formation of lipoxygenase pathway products [leukotriene (LTB4)] in vitro.
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Glafenine
Glafenin
T00553820-67-5
Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of various origins.
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Pranoprofen
Pyranoprofen
T015952549-17-4
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
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Fenoprofen Calcium hydrate
T018471720-56-4
Fenoprofen calcium is a propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.
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Bicalutamide
ICI-176334
T038090357-06-5
Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.
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(S)-(+)-Ibuprofen
Dexibuprofen, (S)-Ibuprofen
T044851146-56-6
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
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7-10 days
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