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Search Result

Search Results for " diuretic "

Targets

Antifungal

95

Compounds

14

Natural Products

1

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T8129 Potassium acetate Diuretic salt,Potassium ethanoate Antifungal
Potassium acetate (Diuretic salt) with antibacterial and antifungal properties.
T10441 Azosemide Na-K-Cl cotransporter
Azosemide is a potent NKCC1 inhibitor (IC50s: 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B).
T21469 Cyclopenthiazide Cyclomethiazide,Su-8341,SU 8341 Others
Cyclopenthiazide (Cyclomethiazide) is a thiazide diuretic used to treat hypertension and heart failure. It decreases the excretion of calcium ions and uric acid and increases the excretion of sodium and potassium ions.
T36125 Tienilic Acid P450
Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity
T0114 Trichlormethiazide Naqua,Metahydrin,Trichlormetazid ATPase , Carbonic Anhydrase
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and ...
T6086 Clopamide Brinaldix,Adurix,Aquex Sodium Channel
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
T1498 Indapamide Veroxil,Noranat,Tertensif Potassium Channel
Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
T6288 Mozavaptan OPC31260l,OPC-31260 Vasopressin Receptor
Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.
T1410 Torsemide AC-4464,JDL-464,Torasemide Na-K-Cl cotransporter
Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...
T6551 Isosorbide Devicoran,Isobide,Hydronol,Dianhydro-D-glucitol,D-Isosorbide Others
Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
T3096 Canrenoate potassium Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone Glucocorticoid Receptor
Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.
T27323 FK-453 FK453,FK 453 Adenosine Receptor
FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.
T71664 Mespirenone Others
Mespirenone is a spironolactone derivative and aldosterone antagonist with diuretic effects.
T25354L1 (Abs)-DuP 747-HCl
(Abs)-DuP 747-HCl Has analgesic activity and can be used as a diuretic.
TP1114L Leucokinin VIII acetate Leucokinin 8 Others
Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach.
T17266 Xipamide Diurexan,Aquaphor Others
Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger.
T0275 Meticrane Fontiliz,Arresten Chloride channel , Sodium Channel
Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.
T19552 RPH-2823 Others
RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance.
T6835 Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 Dopamine Receptor
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
T1230 Pamabrom Others
Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.
T31777 Fenquizone M.G. 13054 Others
Fenquizone (M.G. 13054), a thiazide-like diuretic, exhibits chronic antihypertensive effect. Fenquizone can be used for the research of oedema and hypertension.
T0435 Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,NSC 75925 COX
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T2322 Fimasartan BR-A-657,Kanarb Apoptosis , RAAS
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has show...
T60351 Acetazolamide sodium OT-302 sodium Carbonic Anhydrase
Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and alt...
T0126 Diazoxide SRG-95213,Sch-6783,Proglycem ATPase , Potassium Channel , Autophagy
Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
T0106 Methazolamide L584601,CL 8490 Carbonic Anhydrase
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
T1449 Hydrochlorothiazide HCTZ Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T8634 8-Bromotheophylline Bromotheophylline Others
8-Bromotheophylline (Bromotheophylline) is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, 8-Bromotheophylline acts as a weak diuretic that has been used al...
T60561 Disulfamide Carbonic Anhydrase
Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in ...
T0083 Eplerenone Epoxymexrenone,CGP 30083,SC-66110 Glucocorticoid Receptor
Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase ...
T68166L Traxanox TFA Traxanox TFA(58712-69-9 Free base) Others
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition...
T4564 Ethacrynic acid Edecrin,Etacrynic Acid,Hydromedin Others , Calcium Channel , NF-κB , GST
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase a...
T35336 Furosemide sodium Frusemide Sodium,Lasix Na-K-Cl cotransporter
Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity ...
T0782 Benzthiazide Aquatag,Lemazide,Dihydrex Carbonic Anhydrase
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ...
T30043 Ampyrimine
Ampyrimine is a Diuretic.
T22660 Chlorothiazide Sodium Others
diuretic and antihypertensive
T29985 Aminometradine Catapyrin,Aminometramide,BRN 0175533
Aminometradine is a diuretic agent.
T28872 SU 15049A SU15049A,SU-15049A
SU 15049A is a diuretic agent.
T34955 Tripamide
Tripamide is a type of diuretic.
T24669 Protheobromine Pro-Cor,Theocor,Protheobrominum,TEBE,Vascopil
Protheobromine is a diuretic drug.
T29498 A 56234 A56234,A-56234
A 56234 is a high-ceiling diuretic.
T29510 A-49816 hydrochloride A-49816 HCl
A-49816 hydrochloride is a diuretic.
T33297 Mersalyl Diursal,Salyrgan,Igrosin,Salurin,Mercuramide
Mersalyl is an organic mercurial diuretic.
T31419 Diapamide CN-36337,D-1593,CN-36,337,D 1593
Diapamide is a new diuretic and antihypertensive agent.
T34469 S 8666 S8666
S 8666 is a potent diuretic with uricosuric action.
T21416 Hydroflumethiazide Diurometon,Glomerulin,Diuredemina,Flutizide,Hidroflumetiazid
Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.
T29864 Alilusem Alilusem potassium,M 17055,M17055,D09772
Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.
T26565 Adentri BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124
Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity.
T19430 Indacrinone MK-196,Indacrynic acid Others
Indacrinone is an investigational diuretic.
T30973 Clofenamide Aponiere,Haflutan,Frictan,Eleklin,Indigatin
Clofenamide is a low-ceiling sulfonamide diuretic.

Compounds

Potassium acetate
T8129
Synonym: Diuretic salt,Potassium ethanoate
Target: Antifungal
Azosemide
T10441
Synonym:
Target: Na-K-Cl cotransporter
Cyclopenthiazide
T21469
Synonym: Cyclomethiazide,Su-8341,SU 8341
Target: Others
Tienilic Acid
T36125
Synonym:
Target: P450
Trichlormethiazide
T0114
Synonym: Naqua,Metahydrin,Trichlormetazid
Target: ATPase, Carbonic Anhydrase
Clopamide
T6086
Synonym: Brinaldix,Adurix,Aquex
Target: Sodium Channel
Indapamide
T1498
Synonym: Veroxil,Noranat,Tertensif
Target: Potassium Channel
Mozavaptan
T6288
Synonym: OPC31260l,OPC-31260
Target: Vasopressin Receptor
Torsemide
T1410
Synonym: AC-4464,JDL-464,Torasemide
Target: Na-K-Cl cotransporter
Isosorbide
T6551
Synonym: Devicoran,Isobide,Hydronol,Dianhydro-D-glucitol,D-Isosorbide
Target: Others
Canrenoate potassium
T3096
Synonym: Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone
Target: Glucocorticoid Receptor
FK-453
T27323
Synonym: FK453,FK 453
Target: Adenosine Receptor
Mespirenone
T71664
Synonym:
Target: Others
(Abs)-DuP 747-HCl
T25354L1
Synonym:
Target:
Leucokinin VIII acetate
TP1114L
Synonym: Leucokinin 8
Target: Others
Xipamide
T17266
Synonym: Diurexan,Aquaphor
Target: Others
Meticrane
T0275
Synonym: Fontiliz,Arresten
Target: Chloride channel, Sodium Channel
RPH-2823
T19552
Synonym:
Target: Others
Fenoldopam mesylate
T6835
Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526
Target: Dopamine Receptor
Pamabrom
T1230
Synonym:
Target: Others
Fenquizone
T31777
Synonym: M.G. 13054
Target: Others
Sulfinpyrazone
T0435
Synonym: (+/-)-Sulfinpyrazone,G-28315,NSC 75925
Target: COX
Fimasartan
T2322
Synonym: BR-A-657,Kanarb
Target: Apoptosis, RAAS
Acetazolamide sodium
T60351
Synonym: OT-302 sodium
Target: Carbonic Anhydrase
Diazoxide
T0126
Synonym: SRG-95213,Sch-6783,Proglycem
Target: ATPase, Potassium Channel, Autophagy
Methazolamide
T0106
Synonym: L584601,CL 8490
Target: Carbonic Anhydrase
Hydrochlorothiazide
T1449
Synonym: HCTZ
Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad
8-Bromotheophylline
T8634
Synonym: Bromotheophylline
Target: Others
Disulfamide
T60561
Synonym:
Target: Carbonic Anhydrase
Eplerenone
T0083
Synonym: Epoxymexrenone,CGP 30083,SC-66110
Target: Glucocorticoid Receptor
Traxanox TFA
T68166L
Synonym: Traxanox TFA(58712-69-9 Free base)
Target: Others
Ethacrynic acid
T4564
Synonym: Edecrin,Etacrynic Acid,Hydromedin
Target: Others, Calcium Channel, NF-κB, GST
Furosemide sodium
T35336
Synonym: Frusemide Sodium,Lasix
Target: Na-K-Cl cotransporter
Benzthiazide
T0782
Synonym: Aquatag,Lemazide,Dihydrex
Target: Carbonic Anhydrase
Ampyrimine
T30043
Synonym:
Target:
Chlorothiazide Sodium
T22660
Synonym:
Target: Others
Aminometradine
T29985
Synonym: Catapyrin,Aminometramide,BRN 0175533
Target:
SU 15049A
T28872
Synonym: SU15049A,SU-15049A
Target:
Tripamide
T34955
Synonym:
Target:
Protheobromine
T24669
Synonym: Pro-Cor,Theocor,Protheobrominum,TEBE,Vascopil
Target:
A 56234
T29498
Synonym: A56234,A-56234
Target:
A-49816 hydrochloride
T29510
Synonym: A-49816 HCl
Target:
Mersalyl
T33297
Synonym: Diursal,Salyrgan,Igrosin,Salurin,Mercuramide
Target:
Diapamide
T31419
Synonym: CN-36337,D-1593,CN-36,337,D 1593
Target:
S 8666
T34469
Synonym: S8666
Target:
Hydroflumethiazide
T21416
Synonym: Diurometon,Glomerulin,Diuredemina,Flutizide,Hidroflumetiazid
Target:
Alilusem
T29864
Synonym: Alilusem potassium,M 17055,M17055,D09772
Target:
Adentri
T26565
Synonym: BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124
Target:
Indacrinone
T19430
Synonym: MK-196,Indacrynic acid
Target: Others
Clofenamide
T30973
Synonym: Aponiere,Haflutan,Frictan,Eleklin,Indigatin
Target:
1 2
Cat No. Product Name Synonyms Targets
T2780 Catalpol Catalpinoside,Digitalis purpurea L Others , HBV
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T0354 Canrenone 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,RP-11614,SC14266 Glucocorticoid Receptor , Endogenous Metabolite
Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.
T6S2238 Eupalinolide B Others
Eupalinolide A has the effects of relieving phlegm and relieving cough, clearing away heat and detoxification, diuretic swelling and reducing blood pressure.
T4959 DL-Mannitol Mannitol Others
DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake
T2S0265 Robinin NSC 9222 TLR
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR...
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T0332 D-Sorbitol Glucitol,Sorbitol,D-Glucitol Others , Endogenous Metabolite
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use...
T0414 D-Mannitol Mannite,Mannitol,Osmitrol Apoptosis , Dehydrogenase , Endogenous Metabolite
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to t...
T0892 Diphylline Dyphylline,Diprophylline PDE , Adenosine Receptor
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies...
TN4967 Scoparinol
Scoparinol has sedative, anti-inflammatory, analgesic, and diuretic actions.
T83522 (S)-(+)-Imperanene
(S)-(+)-Imperanene, a compound with diuretic and anti-inflammatory properties [1], can be isolated from the plant Imperata cylindrica.
TN1681 Gentianine Others , TNF , transporter , PPAR
Gentianine is an effective Swertiamarin derivative, which has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, diuretic and other effects, and has the potential to be developed into a safe antihypertensive d...
T80019 17-Hydroxyneomatrine
17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical carcinoma Hela cell growth, along with broad-spectrum antibacteria...
T81117 Spilanthol
Spilanthol, an orally active compound with analgesic, neuroprotective, antioxidant, antimutagenic, anti-cancer, anti-inflammatory, antimicrobial, and insecticidal properties, facilitates the induction of cAMP, thereby in...

Natural Products

Catalpol
T2780
Synonym: Catalpinoside,Digitalis purpurea L
Target: Others, HBV
Canrenone
T0354
Synonym: 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,RP-11614,SC14266
Target: Glucocorticoid Receptor, Endogenous Metabolite
Eupalinolide B
T6S2238
Synonym:
Target: Others
DL-Mannitol
T4959
Synonym: Mannitol
Target: Others
Robinin
T2S0265
Synonym: NSC 9222
Target: TLR
Theophylline
T1083
Synonym: Theo-24,1,3-Dimethylxanthine
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
D-Sorbitol
T0332
Synonym: Glucitol,Sorbitol,D-Glucitol
Target: Others, Endogenous Metabolite
D-Mannitol
T0414
Synonym: Mannite,Mannitol,Osmitrol
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite
Diphylline
T0892
Synonym: Dyphylline,Diprophylline
Target: PDE, Adenosine Receptor
Scoparinol
TN4967
Synonym:
Target:
(S)-(+)-Imperanene
T83522
Synonym:
Target:
Gentianine
TN1681
Synonym:
Target: Others, TNF, transporter, PPAR
17-Hydroxyneomatrine
T80019
Synonym:
Target:
Spilanthol
T81117
Synonym:
Target:

Recombinant Proteins

Species：
Human (1)
Expression System：
HEK293 (1)
Tag：
hFc (1)
Cat No. Product Name Species Expression System
TMPY-02839 Adrenomedullin Protein, Human, Recombinant (hFc) Human HEK293
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the ca...
Cat No. Product Name
L7110 Anti-Hypertension Compound Library

719 compounds
719 hypertension-related small molecules for high-throughput and high-content screening.

Libraries

Anti-Hypertension Compound Library
L7110
Compounds: 719
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