d36

Tetrabutylammonium-d36iodide (Tetra-n-butylammonium-d36iodide) is a deuterium-labeled form of tetrabutylammonium iodide. This quaternary ammonium salt is commonly utilized as a phase transfer catalyst, surfactant, and stabilizer in various chemical reactions, particularly within organic synthesis. It has unique chemical properties that facilitate the transfer of ions or molecules between phases, making it an essential component in diverse industrial processes.

Tetrabutylammonium-d36chloride [IPC-TBA-Cl-d36chloride] is the deuterium-labeled form of tetrabutylammonium (chloride).

Tetrabutylammonium-d36bromide (AP 6G-d36bromide) is the deuterium-labeled variant of Tetrabutylammonium bromide. This organic ammonium salt is primarily employed as a catalyst in various reactions and purification processes. Known for its significant catalytic effects in organic synthesis, it serves as a surfactant, stabilizer, and antimicrobial agent. Additionally, it is utilized in laboratory research as an ion exchanger and solvent extractant.

Pentadecylbenzene-d36-1 (1-Phenylpentadecane-d36) is a deuterium-labeled form of Pentadecylbenzene.

D36 is an androgen receptor allosteric antagonist. It also has inverse agonist properties.

KD36 is a selective KRAS-G12C inhibitor with an IC50 value of 0.92 μM. It suppresses the phosphorylation of ERK and AKT, induces the accumulation of reactive oxygen species (ROS), and reduces mitochondrial membrane potential, leading to apoptosis in KRAS-G12C mutant cells. KD36 is applicable in research related to non-small cell lung cancer (NSCLC).

CPD3615-A5 is an active chemical.

OD36 is a selective and potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 inhibits ALK2 signaling and osteogenic differentiation (KD: 37 nM), and binds efficiently to the ALK2 kinase ATP pocket.

OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride targets ALK2. OD36 hydrochloride targets ALK2 with a KD of 37 nM.

AZD3676 is a novel dual antagonist of serotonin 5-HT1A and 5-HT1B receptor.

Thrombospondin-1 (TSP-1)-derived CD36 binding motif is a bioactive peptide cyclized by a disulfide bond, critical for TSP-1-CD36 interaction. Involved in cancer metastasis, tumor adhesion, and angiogenesis, this matrix-bound glycoprotein-origin peptide competitively inhibits platelet aggregation and tumor metastasis.

Anti-Mouse TIM-1/CD365 Antibody (3B3) is an IgG2a, κ antibody inhibitor derived from rats, targeting the TIM-1/CD365 in mice.

Anti-CD36 Antibody is a humanized monoclonal antibody targeting CD36 (Fatty Acid Translocase/FAT). CD36 is a multi-ligand scavenger receptor widely expressed on monocytes/macrophages, platelets, endothelial cells, and adipocytes, facilitating the uptake of long-chain fatty acids (LCFA) and the binding of oxidized low-density lipoproteins (oxLDL). By specifically binding to CD36, this antibody blocks fatty acid transport or inhibits oxLDL-induced foam cell formation, making it a valuable tool for research in metabolic disorders (e.g., atherosclerosis, diabetes) and cancer lipid metabolism.

Anti-Mouse TIM-1/CD365 Antibody (3D10) is a rat-derived monoclonal antibody that specifically binds to and blocks T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1). Anti-Mouse TIM-1/CD365 Antibody (3D10) is primarily used for functional blocking experiments both in vivo and in vitro. Anti-Mouse TIM-1/CD365 Antibody (3D10) exhibits dual regulatory effects in vivo: it exacerbates lesion development in atherosclerosis models while effectively reducing disease severity in graft-versus-host disease (GVHD) models.

The Anti-TIM-1/KIM-1/CD365 Antibody (2.70.2) is a type of antibody targeting TIM/KIM-1/CD365.

Anti-Mouse TIM-1/CD365 Antibody (RMT1-10) is an antibody targeting TIM-1/CD365 and can be used for immunology research.

LCD36 is a derivative of nicotinamide adenine dinucleotide (NAD) and is utilized in the synthesis of PARP-1 tracers for positron emission tomography (PET) imaging to detect PARP-1 enzyme activity.

CD36 Peptide P (139-155), Cys conjugated, a Cys-labelled variant of CD36 Peptide, can inhibit CD36's immunoadsorption by OKM5 [1].

CD36 Peptide P (93-110), Cys conjugated, a Cys-labelled CD36 Peptide, blocks the binding of CD36 to immobilized thrombospondin and partially inhibits collagen-induced platelet aggregation [1].

SD-36 is a selective and efficient STAT3 protein degrader (Kd=~50 nM) with antitumor activity that promotes growth inhibition and induces apoptosis by inhibiting Mcl-1 in gliomas.SD-36 inhibits the transcriptional activity of STAT3.

SD-36 TFA is a selective and highly efficient STAT3 degrader with a Kd value of about 50 nM.SD-36 has anticancer and antitumor activity, and can break down mutant STAT3 proteins in cells and inhibit STAT3 transcription.SD-36 promotes growth inhibition and induces apoptosis through inhibition of Mcl-1 in gliomas.

2-Bromoquinoxaline ,with CAS No. 36856-91-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Bromoquinoxaline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine ,with CAS No. 3680-69-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1H-Isoindol-1-one,2,3-dihydro-4-methoxy- ,with CAS No. 366453-22-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-Isoindol-1-one,2,3-dihydro-4-methoxy- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.