d36

D36 is an androgen receptor allosteric antagonist. It also has inverse agonist properties.

CPD3615-A5 is an active chemical.

OD36 is a selective and potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 inhibits ALK2 signaling and osteogenic differentiation (KD: 37 nM), and binds efficiently to the ALK2 kinase ATP pocket.

OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride targets ALK2. OD36 hydrochloride targets ALK2 with a KD of 37 nM.

AZD3676 is a novel dual antagonist of serotonin 5-HT1A and 5-HT1B receptor.

Thrombospondin-1 (TSP-1)-derived CD36 binding motif is a bioactive peptide cyclized by a disulfide bond, critical for TSP-1-CD36 interaction. Involved in cancer metastasis, tumor adhesion, and angiogenesis, this matrix-bound glycoprotein-origin peptide competitively inhibits platelet aggregation and tumor metastasis.

Anti-Mouse TIM-1/CD365 Antibody (3B3) is an IgG2a, κ antibody inhibitor derived from rats, targeting the TIM-1/CD365 in mice.

Anti-CD36 Antibody is a human-sourced antibody expressed in CHO cells, targeting CD36. It possesses a huIgG1 heavy chain and a huκ light chain, with an estimated molecular weight (MW) of 150 kDa. For isotype control, please refer to HumanIgG1kappa, Isotype Control.

CD36 Peptide P (139-155), Cys conjugated, a Cys-labelled variant of CD36 Peptide, can inhibit CD36's immunoadsorption by OKM5 [1].

CD36 Peptide P (93-110), Cys conjugated, a Cys-labelled CD36 Peptide, blocks the binding of CD36 to immobilized thrombospondin and partially inhibits collagen-induced platelet aggregation [1].

SD-36 is a selective and efficient STAT3 protein degrader (Kd=~50 nM) with antitumor activity that promotes growth inhibition and induces apoptosis by inhibiting Mcl-1 in gliomas.SD-36 inhibits the transcriptional activity of STAT3.

SD-36 TFA is a selective and highly efficient STAT3 degrader with a Kd value of about 50 nM.SD-36 has anticancer and antitumor activity, and can break down mutant STAT3 proteins in cells and inhibit STAT3 transcription.SD-36 promotes growth inhibition and induces apoptosis through inhibition of Mcl-1 in gliomas.

2-Bromoquinoxaline ,with CAS No. 36856-91-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Bromoquinoxaline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Chloro-7H-pyrrolo[2,3-d]pyrimidine ,with CAS No. 3680-69-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9ci) ,with CAS No. 366453-22-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-Isoindol-1-one,2,3-dihydro-4-methoxy-(9ci) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Triphenylmethyl mercaptan ,with CAS No. 3695-77-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Triphenylmethyl mercaptan provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Amino-3-cephem-4-carboxylic acid ,with CAS No. 36923-17-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Amino-3-cephem-4-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.

Pratosartan is a selective antagonist of angiotensin II receptor.

E3 ligase Ligand 36 is an E3 ligase ligand that can be utilized for synthesizing PROTACs, such as PROTAC BRM/BRG1 degrader-1.

VHL Ligand 36 is a ligand of the von Hippel-Lindau (VHL) protein. It is used in the synthesis of SD-2301.

CCD-3693 is a gamma-aminobutyric acid (GABA) receptor agonist.

DMBT is an inhibitor of invasion and metastasis through Akt/GSK-3β/β-catenin pathway in B16BL6 cells.

3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling proteins related with cell prolifer