bad

BAD (103-127) (human) acetate is a 25-mer Bad polypeptide from the BAD BH3 domain that antagonizes the effects of Bcl-xl.

BAD (103-127) (human) is a 25-mer peptide obtained from the BH3 domain of BAD. It effectively counteracts the activity of Bcl-xL. Notably, BAD (103-127) (human) exhibits an approximately 800-fold greater binding affinity for Bcl-xL compared to the 16-mer peptide.

NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)

CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good biological activity and kinase specificity.

CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).

BAD (103-127) (human), a FAM-labeled 25-mer peptide derived from the BH3 domain of human BAD, antagonizes the function of Bcl-xL [1].

Bad BH3 (mouse) is a bioactive peptide derived from the BH3 domain (a death domain) of Bad, comprising amino acid residues 140 to 165, and functions by binding to bcl-2.

BAD (103-127) (human), FAM-labeled TFA, is a FAM-tagged human peptide corresponding to the 25-mer Bad segment from the BH3 domain of BAD. This compound functions as an antagonist to Bcl-xL.

DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.

Kazinol A shows strong inhibition of arachidonic acid (AA)-induced platelet aggregation. It also exhibits potent inhibition with IC50 values ranging 0.6-164 M against XOD. Kazinol A may be a candidate for the development of effective anti-cancer drug on h

Carbadox (Mecadox) is an antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity.

Barbadin is a novel and specific inhibitor of β-arrestin/β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.

Euphorbadienol is a triterpenoid compound isolated from the latex of Euphorbia resinifera. Its derivatives can act as resistance inducers and also exhibit anti-leishmanial and anti-melanoma activities.

PPARγ antagonist

Carnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities.1,2 It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8, and 14.9 μM, respectively).2 |1. Piatak, D.M., and Reimann, K.A. Plant investigations IV. Corollatadiol A new triterpene from euphorbia corollata. Tetrahedron Lett. 13(44), 4525-4528 (1972).|2. de Almeida, B.C., Araújo, B.Q., Carvalho, A.A., et al. Antiprotozoal activity of extracts and isolated triterpenoids of 'carnauba' (Copernicia prunifera) wax from Brazil. Pharm. Biol. 54(12), 3280-3284 (2016).

Desoxycarbadox, derived from Carbadox, is a quinoxaline-di-N-oxide antibiotic compound.

Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes. It shows promise in the development of cardio- and neuroprotective agents owing to its mechanisms of action, which include antioxidant properties and free radical scavenging [1].

1,2-Dicarbadodecaborane(12)-1-thiol-10B10 is the boron-10 (10B) labeled form of 1,2-Dicarbadodecaborane(12)-1-thiol.

1,2-Dicarbadodecaborane(12)-10B10 is 1,2-Dicarbadodecaborane(12) labeled with boron-10 (10B).

Carbadox (Standard) is the standard substance of Carbadox, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Carbadox (Mecadox) is an antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity.

Desoxycarbadox‑D3 (Standard) is a reference standard of Desoxycarbadox‑D3 intended for quantitative analysis, quality control, and related biochemical research applications.

Carbadox-D3 (Standard) is a reference standard of Carbadox-D3 intended for quantitative analysis, quality control, and related biochemical research applications.

Badione A is a compound that can be found in Xerocomus badius and is capable of forming stable salts with potassium ions.

Himbadine (compound 5) is a synthesized compound produced through specific chemical reactions and is an intermediate in the synthesis of (-)-himgaline.