ldh — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11829	LDH-IN-1		Dehydrogenase
	LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).		Dehydrogenase
T5705	Glomeratose A		Dehydrogenase
	Glomeratose A is a lactate dehydrogenase inhibitor.		Dehydrogenase
T15435	GSK2837808A		Dehydrogenase
	GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).		Dehydrogenase
T22336	Galloflavin		Dehydrogenase
	Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.		Dehydrogenase
T4295	(R)-GNE-140	GNE-140	Dehydrogenase
	(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.		Dehydrogenase
T12438	PfDHODH-IN-1		Dehydrogenase , Parasite
	PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.		Dehydrogenase , Parasite
T11546	HDHODH-IN-1		Dehydrogenase
	hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.		Dehydrogenase
T7964	Isomalt	Palatinitol,Palatinit	Others , Dehydrogenase
	Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside		Others , Dehydrogenase
T3175	LDHA-IN-4	AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase
	LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.		Dehydrogenase
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T5S0620	3-Dehydrotrametenolic acid	Dehydrotrametenolic acid	Apoptosis , Others , Dehydrogenase
	1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug.		Apoptosis , Others , Dehydrogenase
T5325	Nifurtimox	BAY-2502,BAY-A-2502	Dehydrogenase , Parasite
	Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi- epimastigotes, respectively).		Dehydrogenase , Parasite
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
T60240	ALDH1A3-IN-2		Dehydrogenase
	ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.		Dehydrogenase
T39805	LDHA-IN-3	PSTMB,1-(phenylseleno)-4-(trifluoromethyl) benzene	Dehydrogenase
	LDHA-IN-3 (1-(phenylseleno)-4-(trifluoromethyl) benzene) is a potent non-competitive lactate dehydrogenase (LDHA) inhibitor with an IC50 value of 145.2 nM.LDHA-IN-3 is a selenobenzene compound that can be used in cancer ...		Dehydrogenase
T67832	ALDH2 modulator 1		Dehydrogenase
	ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.		Dehydrogenase
T63341	ALDH1A1-IN-2		Dehydrogenase
	ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity.		Dehydrogenase
T60372	ALDH3A1-IN-1
	ALDH3A1-IN-1 (Compound 18) is a potent ALDH3A1 inhibitor with an IC 50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination...
T64347	ALDH1A3-IN-3		Dehydrogenase
	ALDH1A3-IN-3 (compound 16), a powerful ALDH1A3 inhibitor with an IC50 of 0.26 μM, serves as an effective ALDH3A1 substrate. It is utilized in prostate cancer research.		Dehydrogenase
T61339	LDHA/PDKs-IN-1
	LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, displaying IC50 values of 0.8 μM and 0.15 μM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 μM), reduc...