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virus replication

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    209
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Compound_Libraries
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    7
    TargetMol | Peptide_Products
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    TargetMol | PROTAC
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    33
    TargetMol | Recombinant_Protein
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    TargetMol | Disease_Modeling_Products
hDHODH-IN-3
DHODH-IN-2
T110251644156-80-8In house
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.
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6-8 weeks
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hDHODH-IN-4
DHODH-IN-5
T110281644156-56-8In house
hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8.
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6-8 weeks
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Fiacitabine
FOAC, FIAC, NSC 382097
T1528069123-90-6In house
Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively).
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Lagociclovir
MIV-210
T1570492562-88-4In house
Lagociclovir (MIV-210), a nucleoside analogue, is an antiviral compound available for the treatment of HBV82 that inhibits the replication of wild-type hepatitis B virus (HBV) in human hepatocellular carcinoma cell lines that permanently express HBV.
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6-8weeks
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Azaribine
NSC 67239, 2',3',5'-Tri-O-acetyl-6-azauridine
T251302169-64-4In house
Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has been used in the study of Zika virus (ZIKV) infections, and in the study of psoriasis, arthritis and mycosis fungoides. Azaribine is used to study Zika virus (ZIKV) infections, psoriasis and mycosis fungoides.
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7-10 days
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CF-1743
CF1743
T26987319425-66-6In house
CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication. CF-1743 can be used in studies about infection of varicella and herpes zoster.
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6-8 weeks
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TargetMol | Inhibitor Sale
β-Thujaplicinol
T288594356-35-8In house
ß-Thujaplicinol, a hydroxylated thujaplicinone isolated from western red cedar heartwood, has antiviral activity, inhibits hepatitis B virus replication by blocking viral ribonuclease H activity, and can be used in the study of viral infections.
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7-10 days
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YM-53403
T29187851331-05-0In house
YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections.
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6-8 weeks
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TargetMol | Inhibitor Sale
Trifluoromethyl-tubercidin
T677531854086-05-7In house
Trifluoromethyl-tubercidin (TFMT) inhibits host MTr1 and suppresses virus replication. TFMT inhibits MTr1 through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT was effective in inhibiting viral replication in mice, displayed little toxicity.
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Ensitrelvir
S-217622
T97162647530-73-0In house
Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM.
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Entecavir monohydrate
SQ 34676, Entecavir hydrate, BMS-200475
T0085209216-23-9
Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.
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Foscarnet sodium
Phosphonoformate
T022063585-09-1
Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
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Ganciclovir
RS-21592, BW 759, 2'-Nor-2'-deoxyguanosine
T068882410-32-0
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
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Isoliquiritigenin
Isoliquiritigen, ISL, GU17
T0725961-29-5
Isoliquiritigenin (ISL) is a flavonoid natural product that inhibits influenza virus replication (EC50=24.7 μM) and aldose reductase activity (IC50=320 nM). Isoliquiritigenin has antitumor activity.
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1-Docosanol
n-Docosanol, Docosanol, Behenyl alcohol, Behenic alcohol
T0884661-19-8
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex virus envelope, thereby preventing viral entry into cells and subsequent viral activity and replication. 1-Docosanol is used topically in the treatment of recurrent herpes simplex labialis episodes and relieves associated pain and may help heal sores faster.
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HCV-IN-29
T115391009119-83-8
HCV-IN-29 is an inhibitor of the hepatitis C virus (HCV).
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TargetMol | Inhibitor Sale
HCV-IN-30
T115411007882-23-6
HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).
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4-6 weeks
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TargetMol | Inhibitor Sale
Dextran sulfate sodium salt (MW 4500-5500)
DSS, Dextran sulfate sodium salt (MW 4500-5500)
T136479011-18-1
Dextran sulfate sodium salt (MW 4500-5500) is an anhydrous glucose polymer with a molecular weight range of 4500-5500. Dextran sulfate sodium salt (MW 4500-5500) inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells. Dextran sulfate sodium salt (MW 4500-5500) induces inflammation mainly in the colon. It can destroy the integrity of the intestinal mucosal barrier through the high negative charge caused by sulfate groups, leading to intestinal barrier damage, macrophage dysfunction, and bacterial flora disorder.
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Lopinavir
ABT-378
T1623192725-17-0
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor effective against HIV protease with the Val 82 mutation. It is less affected by serum protein binding compared to the structurally related drug ritonavir.
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Ganciclovir sodium
RS-21592 sodium, Cytovene IV sodium, 2'-Nor-2'-deoxyguanosine sodium, BW 759 sodium
T22337107910-75-8
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
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2′-O-Methylcytidine
T382372140-72-9
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)
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Cetylpyridinium Chloride
Cetamium, Pristacin, Hexadecylpyridinium Chloride
T6439123-03-5
Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
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Bz-RS-ISer(3-Ph)-Ome
Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
T705532981-85-4
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size of M-MSV-induced tumors, and influences the immune response by inhibiting PHA-induced proliferation of T lymphocytes.
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Cyclofenil
T83492624-43-3
Cyclofenil is an estrogen antagonist, has anti-dengue-virus activity
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