s 23

S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.

(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6345 and the CAS number is 874287-87-3.

(S)-3-Hydroxy-23-methyltetracosanoyl-CoA ((S)-3-Hydroxy-23-methyltetracosanoyl-coenzyme A) is a derivative of coenzyme A.

(23S,50S)-50-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid is a useful organic compound for research related to life sciences and the catalog number is T64767.

(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].

23S-hydroxy-11,15-dioxo-ganoderic acid DM is a natural product

(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6320 and the CAS number is 1616120-83-2.

(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6332 and the CAS number is 1474062-47-9.

(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6333 and the CAS number is 2281872-79-3.

ROS 234 dioxalate is a potent antagonist of H3 (pKB of 9.46 for Guinea-pig ileum H3-receptor).

TCS 2314 (compound 3) is a potent and selective VLA-4 (α4β1 integrin; CD49d/CD29) antagonist with an IC50 of 4.4 nM. It exhibits high plasma clearance and low oral bioavailability in rats, making it suitable for asthma research.

RS 23579-190 is a highly selective 5-HT receptor antagonist in neuropharmacology. Capable of specifically blocking serotonin-mediated downstream excitatory postsynaptic potentials at picomolar concentrations, it is frequently used to dissect serotonergic signaling pathways within the gastrointestinal enteric nervous system and central cognitive networks.

Highly potent, selective P2Y1 receptor agonist

RS 23597-190 hydrochloride is an indole derivative and a potent, selective 5-HT4 receptor antagonist (pKi = 9.1). It acts by blocking 5-HT4-mediated cAMP accumulation with high selectivity, used for gastrointestinal motility and arrhythmia research.

checkpoint kinase 1 (chk1) inhibitor

S 2337, a synthetic substrate, can be used to estimate Factor X.

ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].

CGS 23885 is a 5-lipoxygenase inhibitor.

1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.

1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.

Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-protease inhibitor used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents.

Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.

3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the p38MAPK , and PI3K/Akt/mTOR/p70S6K pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

Batabulin (T138067) is an antitumor compound that binds covalently and selectively to a subset of the β-tubulin isotypes, disrupting microtubule polymerization. This disruption affects cell morphology, induces cell-cycle arrest, and ultimately leads to apoptotic cell death.