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Anti-CD23 Antibody (2S954)
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Catalog No. TMAY-00531
Alias Fcer2a, FCER2, Fc fragment of IgE receptor II
Anti-CD23 Antibody (2S954) is a Mouse antibody targeting CD23. Anti-CD23 Antibody (2S954) can be used in FCM.
Anti-CD23 Antibody (2S954)
Anti-CD23 Antibody (2S954)
😃Good
Catalog No. TMAY-00531Alias Fcer2a, FCER2, Fc fragment of IgE receptor II
Anti-CD23 Antibody (2S954) is a Mouse antibody targeting CD23. Anti-CD23 Antibody (2S954) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD23 Antibody (2S954) is a Mouse antibody targeting CD23. Anti-CD23 Antibody (2S954) can be used in FCM. |
| Alias | Fcer2a, FCER2, Fc fragment of IgE receptor II |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2S954 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD23 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD23, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD23/FCER2 (rh CD23/FCER2; TMPY-02293; P06734-1; Asp48-Ser321). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Fc fragment of IgE, low affinity II, receptor for (CD23) or CD23 antigen is a member of the cluster of differentiation family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD23/FCER2 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Increased levels of soluble CD23/FCER2 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen-specific B-cells, therefore increasing the production of allergen specific IgE. IgE, in turn, is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high-affinity IgE receptor). |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human CD23/FCER2 Protein (TMPY-02293) |
| Antigen Species | Human |
| Biology Area | Fc Receptors, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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