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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4940 | 3-Methylhistamine dihydrochloride | Others , Endogenous Metabolite | |
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere... | |||
T6828 | ZL0420 | Epigenetic Reader Domain | |
ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against B... | |||
T6859 | I-BRD9 | GSK602 | Epigenetic Reader Domain |
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. | |||
T3146 | BMS-202 | PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2 | Apoptosis , PD-1/PD-L1 |
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction. | |||
T14063 | 7α,25-Dihydroxycholesterol | 7α,25-OHC | EBI2/GPR183 , Endogenous Metabolite |
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel... | |||
TP1029 | Thymalfasin | Thymosin α1 | Others |
Thymalfasin (Thymosin α1) (thymosin-alpha 1) is an immunomodulating agent able to enhance the Thl immune response. | |||
T10389L | Aspartyl-alanyl-diketopiperazine acetate | DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base) | Others |
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy. | |||
T21444 | Diphenylcyclopropenone | DPCP,Diphencyprone | Others |
Diphenylcyclopropenone (DPCP) is a topical drug used to treat alopecia areata, alopecia totalis, and refractory warts. Diphencyprone acts as a local stimulator that triggers an immune response against the action of autor... | |||
T0134 | Imiquimod | R 837,S-26308 | SARS-CoV , TLR , Autophagy , HSV |
Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist. | |||
T74140 | β-D-Glucan | Others | |
β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis. | |||
T9107 | NP-G2-044 | Others | |
NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response. | |||
T34295 | Resiniferatoxin | RTX,[3H]resiniferatoxin | IL Receptor |
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. | |||
T5S0993 | Kurarinone | BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT | |
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli... | |||
T4A2462 | Telocinobufagin | Telobufotoxin,Telocinobufogenin | Others |
1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice chall... | |||
T0944 | Levamisole hydrochloride | (-)-Tetramisole hydrochloride | Phospholipase , AChR , Parasite , HSV |
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo... | |||
T23371 | SMER3 | SMER 3 | Others , Ligand for E3 Ligase |
SMER3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune respon... | |||
T78525 | IRG1-IN-1 | Others | |
IRG1-IN-1 is an itaconic acid derivative with the ability to inhibit the activity of Immune Response Gene 1 (IRG1) and is suitable for use in the field of cancer, inflammation and autoimmune disease research. | |||
T11855 | Lipopolysaccharides | LPS | Others |
Lipopolysaccharides (LPS) is a natural product, an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides are highly immunogenic antigens that enhance the immune res... | |||
T10065L | 2',3'-cGAMP sodium | 2'-3'-cyclic GMP-AMP sodium | STING , cGAS |
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm... | |||
T73133 | FGF22-IN-1 | Others | |
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp... |