Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Dopamine Receptor
    (76)
  • 5-HT Receptor
    (25)
  • Adrenergic Receptor
    (11)
  • Histamine Receptor
    (5)
  • Norepinephrine
    (4)
  • Antibacterial
    (1)
  • Apoptosis
    (1)
  • Arrestin
    (1)
  • Autophagy
    (1)
  • Others
    (33)
Filter
Search Result
Results for "

dopamine d3 receptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    117
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
  • Inhibitory Antibodies
    1
    TargetMol | Inhibitory_Antibodies
  • Natural Products
    3
    TargetMol | Natural_Products
  • Isotope Products
    6
    TargetMol | Isotope_Products
  • Antibody Products
    1
    TargetMol | Antibody_Products
Cabergoline
FCE-21336
T1485381409-90-7
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
  • Inquiry Price
Size
QTY
dopamine d3 receptor ligand-1
T62528
Dopamine D3 receptor ligand is a potent, selective, high-affinity compound with 89 times greater selectivity for D3 receptors (Ki: 8 nM) compared to D2 receptors (Ki: 715 nM).
  • Inquiry Price
10-14 weeks
Size
QTY
dopamine d3 receptor antagonist-2
T62946
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor-selective compound (Ki=2.16 nM) that exhibits potential therapeutic effects in CNS disorders.
  • Inquiry Price
10-14 weeks
Size
QTY
Dopamine D3 receptor antagonist-1
T64024
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor-selective or multi-targeting ligand with a Ki value of 1.58 nM, showing therapeutic potential for central nervous system disorders.
  • Inquiry Price
10-14 weeks
Size
QTY
dopamine d3 receptor agonist 13a
T837762899250-94-1
Dopamine D3 receptor agonist 13a selectively targets the dopamine D3 receptor over dopamine D1, D2, and D4 receptors, with affinities (Ki values) of 0.14, 4,600, 2.85, and 756 nM, respectively. It also interacts with serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2B, and 5-HT2C, with Ki values of 6, 54, 1.47, and 252 nM, respectively. While acting as a partial agonist at dopamine D2 receptors (EC50 = 2.26 nM in a G protein recruitment assay), it serves as an antagonist at dopamine D3 receptors (IC50 = 4.62 nM). Additionally, Dopamine D3 receptor agonist 13a, at a dose of 3 mg kg, has been shown to reduce cocaine self-administration in rats.
  • Inquiry Price
Size
QTY
A-437203
ABT-925, A37203, Lu201640
T10213220519-06-2In house
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM.
  • Inquiry Price
6-8 weeks
Size
QTY
PNU-177864 hydrochloride
PNU-177864 (hydrochloride)
T125101783978-03-9In house
PNU-177864 hydrochloride is a potent, selective, and orally active dopamine D3 receptor antagonist that is structurally consistent with a cationic amphiphilic drug (CAD). It induces phospholipidosis in vivo and exhibits antischizophrenic activity.
  • Inquiry Price
6-8 weeks
Size
QTY
SB-277011
SB-277011A
T12861215803-78-4In house
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
  • Inquiry Price
6-8weeks
Size
QTY
Didesmethyl cariprazine
T15117839712-25-3In house
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is a potent D3 preference D3 D2 receptor partial agonist of dopamine for the treatment of schizophrenia, bipolar mania, and depression, with a high affinity for d3 and d2 receptors and a moderate affinity for 5-HT 1A receptors.
  • Inquiry Price
8-10weeks
Size
QTY
TargetMol | Inhibitor Sale
NGD 94-1
T23066178928-68-2In house
NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other psychiatric disorders.
  • Inquiry Price
6-8 weeks
Size
QTY
BP14979
BP-14979, BP-1,4979, BP1,4979, BP 14979, BP 1,4979
T268901000036-77-0In house
BP14979 is a dopamine D3 receptor agonist that can be used to study neurological disorders.
  • Inquiry Price
6-8 weeks
Size
QTY
Aplindore Fumarate
DAB-452 Fumarate, DAB452 Fumarate
T30098189681-71-8In house
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-HT2), and α1-adrenergic receptors.Aplindore Fumarate is used in the study of Parkinson's disease and schizophrenia. Fumarate can be used to study Parkinson's and schizophrenia.
  • Inquiry Price
6-8weeks
Size
QTY
TargetMol | Inhibitor Sale
Trazpiroben
TAK-906
T387541352993-39-5In house
Trazpiroben (TAK-906) is a selective dopamine D2 D3 receptor antagonist utilized in gastroparesis research.
  • Inquiry Price
7-10 days
Size
QTY
SKF83959
T6083580751-85-5In house
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent variant modulator of the sigma (σ)-1 receptor, which ameliorates cognitive dysfunction for the study depression and Alzheimer's disease.
  • Inquiry Price
6-8 weeks
Size
QTY
sb-277011 hydrochloride
SB-277011A hydrochloride, SB 277011A hydrochloride, SB 277011 hydrochloride
T63096215804-67-4In house
SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, and orally active dopamine D3 receptor (D3R) antagonist that crosses the blood-brain barrier, with Ki values of 10.7 nM for rodent D3R and 11.2 nM for human D3R. It is 80-100 times more selective for D3 receptors than other dopamine receptors, acting on D3 receptors (pKi: 8.0), D2 receptors (pKi: 6.0), 5-HT1B receptors (pKi < 5.2), and 5-HT1D receptors (pKi: 5.9).
  • Inquiry Price
7-10 days
Size
QTY
Perphenazine dihydrochloride
T631152015-28-3In house
Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist that acts on D2 (Ki: 0.56 nM), D3 (Ki: 0.43 nM), and 5-HT2A (Ki: 0.6 nM) receptors, and also binds Alpha-1A adrenergic receptors. It can induce apoptosis, inhibit cancer cell proliferation, and is used to study psychiatric disorders, cancer, and inflammation.
  • Inquiry Price
6-8 weeks
Size
QTY
Fallypride
T70302166173-78-0In house
Fallypride is a potent and selective dopamine D2 D3 receptor antagonist.
  • Inquiry Price
6-8 weeks
Size
QTY
Ziprasidone hydrochloride monohydrate
CP 88059
T0031138982-67-9
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
  • Inquiry Price
Size
QTY
Ziprasidone hydrochloride
Ziprasidone HCl, CP-88059 hydrochloride
T0031L122883-93-6
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
  • Inquiry Price
Size
QTY
Chlorprothixene
Truxal, Taractan, Clorprotixeno
T0074113-59-7
Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.
  • Inquiry Price
Size
QTY
Risperidone
Risperidal, R 64 766
T0351106266-06-2
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
  • Inquiry Price
Size
QTY
Pramipexole
SND 919
T1476104632-26-0
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not been implicated in cases of clinically apparent acute liver injury.
  • Inquiry Price
Size
QTY
L-(R,S)-Tetrahydropalmatine
TETRAHYDROPALMATINE HYDROCHLORIDE
T271410097-84-4
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang.
  • Inquiry Price
Size
QTY
Piribedil
EU-4200, Trivastan, ET-495, Trivastal
T32783605-01-4
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
  • Inquiry Price
Size
QTY