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C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squamous carcinoma cells in vitro.[4] C24 dihydro Ceramide levels are also increased in INS-1 β-cells incubated with glucose and palmitate.[5]

C24:1 Ganglioside GM1 (d18:1/24:1) (ammonium) is a monosialylated ganglioside containing nervonic acid.

C24 Ceramide (d18:1(14Z)/24:0) is a type of ceramide utilized in obesity research.

C24:1 Ganglioside GM2 (d18:1/24:1) (ammonium) is an endogenous monosialylated ganglioside and a self-lipid capable of binding to CD1d in HEK293T cells.

C24:1 Ganglioside GM1 (d18:1/24:1) (C24:1-GM1) is a monosialylated ganglioside that contains nervonic acid.

C24:1 Ganglioside GM2 (d18:1/24:1) (C24:1-GM2) is a monosialylated ganglioside that contains nervonic acid.

Lipid C24, a cationic ionizable compound, plays a crucial role in creating lipid nanoparticles (LNPs) and is utilized in nucleic acid delivery research [1].

C24-Ceramide, a sphingolipid utilized in the composition of lipid membranes, induces time-dependent modifications in membrane properties and promotes membrane reorganization [1] [2].

C24:1 Ceramide (d18:1/24:1(15Z)) (Standard) is a reference standard for research and analysis in studies involving C24:1 Ceramide (d18:1/24:1(15Z)).

C24 dihydro Ceramide (d18:0/24:0) (Standard) is a reference standard for research and analysis in studies involving C24 dihydro Ceramide (d18:0/24:0). C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin. It is found in higher concentrations in female sebum compared to male sebum.

C24:1 1-Deoxyceramide (m18:1(14Z)/24:1) (C24:1 Ceramide (m18:1/24:1)) is an analogue of ceramide.

C24:1 GD2 Ceramide (d18:1/24:1) is a type of sphingoid base linked to a fatty acid. It can interact with other membrane lipids, securing GD2 firmly on the cell surface.

C24:1 GB3 Ceramide (d18:1/24:1) is a globoside utilized in the formation of lipid nanoparticles for drug delivery purposes.

C24:1 GB4 Ceramide (d18:1/24:1) is a type of sphingolipid.

C24 Glucosyl(β) ceramide (d18:1/24:0) is a type of galactosyl sphingolipid.

C24:1 GM3 Ceramide (d18:1/24:1) is a glycosphingolipid that can be utilized in creating lipid nanoparticles for drug delivery.

C24:0(2R-OH) Mono-sulfo galactosyl(β) ceramide (d18:1/24:0) is a type of 2-hydroxyceramide.

YLF-466D (C24) is a novel AMPK activator that inhibits platelet aggregation.

Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mouse splenocytes in vitro.

C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemical structure of native 1-deoxysphingosine. J. Lipid Res. 57(7), 1194-1203 (2016).|2. Alecu, I., Othman, A., Penno, A., et al. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J. Lipid Res. 58(1), 60-71 (2017).|3. Alecu, I., Tedeschi, A., Behler, N., et al. Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J. Lipid. Res. 58(1), 42-59 (2017).|4. Schwartz, N.U., Mileva, I., Gurevich, M., et al. Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins Other Lipid Mediat. 141, 40-48 (2019).

C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytosphingosine (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.

C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 1-Deoxyceramide (m18:1/24:1(15Z)) is 1246298-58-7.

C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0) is a lipid molecule that can be used in life science related research. The CAS number of C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0) is 164989-36-0.

C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is 1246298-60-1.