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Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine, is a 4-amino acid peptide known for its blood pressure-lowering effects and its role as an angiotensin-converting enzyme (ACE) inhibitor. This compound is frequently used in high blood pressure research.

GP(33-41) TFA, a 9-amino-acid (aa) peptide, represents the optimal sequence of the lymphocytic choriomeningitis virus GP1 epitope, effectively upregulating H-2D b molecules on the RMA-S (Db Kb) cell surface with an SC50 value of 344 nM [1].

α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, with a binding constant (K B) of approximately 100 nM, and serves as a partial agonist for the CRF1 receptor, exhibiting a half-maximal effective concentration (EC 50) of 140 nM [1] [2].

[Ala11,D-Leu15]-Orexin B(human) TFA is a potent, selective agonist for the orexin-2 receptor (OX2), demonstrating 400-fold higher selectivity for OX2 (EC50=0.13 nM) compared to the orexin-1 receptor (OX1) with an EC50 of 52 nM.

H-Gly-Pro-Gly-NH2, a tripeptide, effectively inhibits HIV-1 replication by interfering with capsid formation, demonstrating antiviral activity particularly against HIV-1 III B and HIV-2 ROD with EC 50 values of 35 µM and 30 µM, respectively. This compound's ability to disrupt the viral replication process positions it as a valuable asset for virus research [1] [2] [3].

hMC1R agonist 1, with an EC 50 of 3 nM, exhibits at least 300-fold higher selectivity for hMC1R compared to hMC3R (EC 50 >902 nM), hMC4R (EC 50 >915 nM), and hMC5R (EC 50 >1000 nM). This compound demonstrates potential for therapeutic applications in targeting the melanocortin family [1].

Aurein 3.1 is an antibiotic antimicrobial peptide, while Aurein 2.6 is active against Gram-positive bacteria, showing minimum inhibitory concentrations (MIC) of 80 μM for M. luteus and 50 μM for S. aureus, S. epidermis, S. mutans, and B. subtilis [1] [2].

Cyclopeptide 2 (Compound 2) is a moderately active antimicrobial peptide against B. subtilis, exhibiting a minimum inhibitory concentration (MIC) of 50 μg mL [1].

S7, a peptide antagonist of the IL-6 receptor, concentration-dependently inhibits IL-6 binding to its receptor. At 50 µM, S7 suppresses IL-6-triggered elevations in VEGF levels within C-33 A cervical cancer cells and RPMI-8226 B cell lymphocytes. It significantly reduces tumor volume in a C-33 A cervical cancer mouse xenograft model with IL-6 overexpression, following a dosage regimen of 50 mg/kg bi-daily. Moreover, when linked to cysteine on lipid nanoparticles (LNPs) encapsulating doxorubicin, S7 enhances glioma targeting and improves survival rates in a U251 glioblastoma mouse xenograft model.

Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina). It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide.