anti-infective

Indomethacin (Indomethacin) is a COX1 and COX2 inhibitor (IC50=18 26 nM) with blood-brain barrier permeability and non-selectivity. Indomethacin is a non-steroidal anti-inflammatory agent with anti-tumor and anti-infective activity.

Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone(NFZ) has also been administered orally in the treatment of TRYPANOSOMIASIS.

Tetracycline (Tetracyclin) is a broad-spectrum antibiotic with inhibitory activity against a wide range of Gram-positive and Gram-negative bacteria, as well as Mycoplasma, Mycoplasma, and Rickettsia. Tetracycline is commonly used in anti-infective studies.

Indomethacin sodium, a powerful and orally active inhibitor of COX1 2, exhibits IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Apart from its potent anti-inflammatory effects, this compound possesses notable anticancer and anti-infective activities. Since it has such versatile attributes, it finds useful applicability in cancer, inflammation, and viral infection research [1] [2] [3].