aldehyde

MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.

Decyl aldehyde is a ten-carbon aldehyde that is a substrate for bacterial luciferase.

Pyruvic aldehyde (2-Oxopropanal) is a highly reactive dicarbonyl compound that can be converted to lactic acid by evolution from DHA and GLA.

Gallic aldehyde shows potent antiviral activity against HSV-1.

Lenalidomide-C9-aldehyde is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-C9-aldehyde can be used in the synthesis of a series of PROTACs, such as INY-03-041. INY-03-041

m-PEG3-aldehyde is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules, which enable selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

23-Aldehyde-16-O-angeloybarringtogenol C (compound 7) is an acid hydrolysis product obtained through oxidative alkaline degradation of camellia seed saponins, which exhibit potential quinone oxidoreductase inducing activity.

Wieland-Gumlich aldehyde is an indoline derived by chemical degradation from strychnine.

Aldehyde Reactive Probe TFA (ARP TFA) is an aldehyde-reactive probe used to detect the level of abasic sites in plant mRNA.

Ursolic aldehyde can inhibit phosphatase of regenerating liver-3, with the IC(50) value of 50 +/- 0.3 mu M.

Changweikang aldehyde is a natural product for research related to life sciences. The catalog number is TN5382 and the CAS number is 2119605-13-7.

Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as well asL. donovaniamastigotes, when used at a concentration of 50 μM.1,2Betulinic aldehyde oxime (50 μM) is cytotoxic to Huh7 hepatocellular carcinoma cells.2

Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor, with a K_i value of 56 pM [1][2].

threo-Guaiacylglycerol-beta-coniferyl aldehyde ether is a useful organic compound for research related to life sciences and the catalog number is T124473.

m-PEG4-CH2-aldehyde is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG4-aldehyde is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2].

Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, designed for synthesizing proteolysis-targeting chimeras (PROTACs) [1].

Acetyl-cyclosporin A aldehyde is a cyclosporin A derivative, a neurocalmodulin inhibitor and cyclophilin binder with potential anti-inflammatory, antitumor, and antiviral activity. It is used in studies of organ transplantation and autoimmune diseases.

Methyltetrazine-PEG4-aldehyde serves as a cleavable 4-unit PEG ADC linker in antibody-drug conjugates (ADCs) synthesis [1]. It functions as a click chemistry reagent, featuring a Tetrazine group capable of undergoing an inverse electron demand Diels-Alder reaction (iEDDA) with TCO-containing molecules.

TCO-PEG3-aldehyde, a cleavable 3-unit PEG ADC linker, is used in the synthesis of antibody-drug conjugates (ADCs) [1]. This click chemistry reagent contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

Biotin-PEG3-aldehyde is a three-unit PEG linker with cleavable properties, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].

Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor used in research on various anemias, including chronic disease-related anemia, chemotherapy-induced anemia, and Diamond-Blackfan anemia.

Oleanolic aldehyde, an antimicrobial agent, effectively hinders the growth of oral pathogens Streptococcus mutans and Porphyromonas gingivalis, implicated in dental caries and periodontal disease. The compound exhibits minimum inhibitory concentrations (MICs) of 488 µg mL and 250 µg mL against these bacteria respectively [1].