cbp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12345	CBP/p300-IN-3	P300/CBP-IN-3	Histone Acetyltransferase
	CBP/p300-IN-3 (P300/CBP-IN-3) is an inhibitor of p300/CBP histone acetyltransferase.		Histone Acetyltransferase
T7264	CBP/EP300-IN-1		Epigenetic Reader Domain
	CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.		Epigenetic Reader Domain
T10717	Inobrodib	CBP-IN-1	Epigenetic Reader Domain
	Inobrodib (CBP-IN-1) is a potent inhibitor of p300/CBP bromodomain.		Epigenetic Reader Domain
T24197	XDM-CBP	XDMCBP,XDM CBP
	XDM-CBP is an effective and selective CBP/p300 bromodomain inhibitor.
T39826	CBP/p300-IN-8	CBP/p300-IN-8
	CBP/p300-IN-8 is a potent inhibitor of the CBP/P300 family of bromodomains . CBP/p300-IN-8 inhibits CBP ( IC 50 =0.01-0.1 μΜ) and BRD4 ( IC 50 =1-1000 μΜ) activity.
T40344	CBP/p300-IN-14	CBP/p300-IN-14
	CBP/p300-IN-14, efficiently inhibits CBP/EP300 (lysine acetyltransferase) with an IC50 value of 3.3 nM.
T10702	CBP/p300-IN-2	CBP/EP300-IN-2	Epigenetic Reader Domain , c-Myc
	CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).		Epigenetic Reader Domain , c-Myc
T40143	PROTAC CBP/P300 Degrader-1	PROTAC CBP/P300 Degrader-1
	PROTAC CBP/P300 Degrader-1 is an effective compound that degrades CBP/P300 in a potent manner. It significantly reduces cell viability in various cancer cell lines.
T12346	CBP/p300-IN-5	P300/CBP-IN-5	Epigenetic Reader Domain
	P300/CBP-IN-5 is a potent inhibitor of p300/CBP histone acetyltransferase (IC50 of 18.8 nM).		Epigenetic Reader Domain
T68895	CBP-93872
	CBP-93872 is a G2 checkpoint inhibitor. CBP-93872 specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint through inhibiting maintenance. CBP-93872 is an inhibitor of maintenance of the DSB-speci...
T40142	Thalidomide-NH-CBP/p300 ligand 2	Thalidomide-NH-CBP/p300 ligand 2
	Thalidomide-NH-CBP/p300 ligand 2 (P-007) is a PROTAC-based compound designed to degrade CBP and p300, acting as a functional antagonist (WO2020173440).
T26962	CBP-307	CBP307
	CBP-307 is a selective second generation S1P1 (a G-protein coupled receptor -GPCR) modulator.
T40144	CBP/p300 ligand 2
	CBP/p300 ligand 2 is a selective ligand that binds to the target protein for PROTAC of dCBP-1, a potent and selective heterobifunctional degrader of p300/CBP.
T12537	β-catenin/CBP-IN-1		Wnt/beta-catenin
	β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin		Wnt/beta-catenin
T79168	CBP-IN-1		Epigenetic Reader Domain
	CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nM and 3100 nM, respectively [1].		Epigenetic Reader Domain
T62415	CBP/p300-IN-17
	CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM).
T3969	I-CBP112		Epigenetic Reader Domain , Histone Acetyltransferase
	I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.		Epigenetic Reader Domain , Histone Acetyltransferase
T63122	CBP/p300-IN-19
	CBP/p300-IN-19 is a potent inhibitor of p300/CBP HAT, which can act on P300-HAT (IC50: 1.4 μM), CBP-HAT (IC50: 1.4 μm), 2.2 μM), PCAF (IC50>100 μM), and Myst3 (IC50>100 μM). CBP/p300-IN-19 has anti-tumor activity.
T63110	CBP/p300-IN-15
	CBP/p300-IN-15 (compound 13a) is a potent inhibitor of p300 (IC50: 2.5 nM) and CBP (IC50: 28.0 nM). p300-IN-15 inhibits OVCAR-3 cells (EC50: 0.865 μM) and A2780 cells (EC50. 2.71 μM). 2.71 μM). CBP/p300-IN-15 can be used...
T62720	CBP/p300-IN-18
	CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).