Melanocortin Receptor

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin receptor system:MC1R，MC2R，MC3R，MC4R，MC5R.

Cat. No.	Product name	CAS No.	Purity
T12882	Setmelanotide	920014-72-8	98%
T12882	Setmelanotide is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
T7627	Adrenocorticotropic Hormone (ACTH) (4-10), human	4037-01-8	98%
T7627	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T20501	Undecylenoyl phenylalanine	175357-18-3	98%
T20501	Undecylenoyl phenylalanine is a novel, skin-lightening agent. It acting as α-melanocyte-stimulating hormone and beta-adrenergic receptor antagonist.
T16879L	SHU 9119 acetate	T16879L
T16879L	SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC...
T12882L	Setmelanotide Acetate(920014-72-8 free base)	T12882L	100%
T12882L	Setmelanotide Acetate is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
TP1248L	ACTH 11-24 acetate(4237-93-8 free base)	TP1248L	100%
TP1248L	ACTH (11-24) acetate is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39)...
TP1898	HS024	212370-59-7	100%
TP1898	Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). In...
TP1893L1	[D-Trp8]-γ-MSH acetate(321351-81-9 free base)	TP1893L1	100%
TP1893L1	Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammato...
TP2015L	HS 014 acetate(207678-81-7 free base)	TP2015L	100%
TP2015L	HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 re...
TP1324	Melanotan (MT)-II	121062-08-6	100%
TP1324	Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).
T7813	α-MSH	581-05-5	100%
T7813	α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
TP1101	Nonapeptide-1 acetate salt (158563-45-2 free base)	TP1101	98%
TP1101	Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt...
T7608	Bremelanotide Acetate	1607799-13-2	98%
T7608	Bremelanotide is an agonist of melanocortin receptor (MCR) .
T7589	Afamelanotide acetate	1566590-77-9	98%
T7589	Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Pro...
TP1952L	PG 106 acetate		98.24%
TP1952L	PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with t...
TP2212L	A-MSH, amide Acetate(581-05-5 free base)	TP2212L	98.67%
TP2212L	a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities....
T8485	THIQ	312637-48-2	98.93%
T8485	THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) TFA	T7627L	99%
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T5464	JNJ-10229570	524923-88-4	99.06%
T5464	JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the produc...
TP1889	MCL0020	475498-26-1	99.18%
TP1889	Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly...