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Melanocortin Receptor

Melanocortin receptors are members of the rhodopsin family of 7-transmembrane G protein-coupled receptors. There are five known members of the melanocortin receptor system:MC1R,MC2R,MC3R,MC4R,MC5R.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79090 Bivamelagon 2641595-54-0 98%
Bivamelagon
MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and ere...
T79091 Bivamelagon hydrochloride 2641595-55-1 98%
Bivamelagon hydrochloride
MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction. ...
T79378 IIIM-8 1128053-62-2 98%
IIIM-8
IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human Adult Epid...
T79996 N,N′-Diferuloylputrescine 42369-86-8 98%
N,N′-Diferuloylputrescine
N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation. It also considerably diminishes the protein expression of MITF an...
T80121 Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2 819048-44-7 98%
Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2
Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH2 is a synthetic cyclic octapeptide that exhibits melanocortin-4 receptor (MC4R) agonism and has been shown to signific...
T80125 ACTH (7-38) (human) 68563-24-6 98%
ACTH (7-38) (human)
ACTH (7-38) (human) is a fragment (7-38) of the full human adrenocorticotropic hormone (ACTH (1-39)), also referred to as corticotropin inhibitory peptide (CIP)....
T80202 Tetrapeptide-1 1632354-04-1 98%
Tetrapeptide-1
Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].
T80540 TCMCB07 1456699-27-6 98%
TCMCB07
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in the...
T80541 TCMCB07 TFA 98%
TCMCB07 TFA
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in manag...
T12882 Setmelanotide 920014-72-8 98%
Setmelanotide
Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
T7627 Adrenocorticotropic Hormone (ACTH) (4-10), human 4037-01-8 98%
Adrenocorticotropic Hormone (ACTH) (4-10), human
Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T69526 PF-07258669 2755890-53-8 99.90%
PF-07258669
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
T16879L SHU 9119 acetate T16879L 99.8%
SHU 9119 acetate
SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC...
TP1004L Beta-MSH (1-22) (human) acetate 99.64%
Beta-MSH (1-22) (human) acetate
Beta-MSH (1-22) (human) acetate (Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)) , is an endogenous melanocortin-4 receptor (MC4-R) agonist.
TP1889 MCL0020 475498-26-1 99.18%
MCL0020
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). ...
T5464 JNJ-10229570 524923-88-4 99.06%
JNJ-10229570
JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiat...
T7627L Adrenocorticotropic Hormone (ACTH) (4-10) TFA T7627L 99%
Adrenocorticotropic Hormone (ACTH) (4-10) TFA
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .
T8485 THIQ 312637-48-2 98.93%
THIQ
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
T9596 AP1189 acetate 959850-74-9 98.73%
AP1189 acetate
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
TP2212L A-MSH, amide Acetate(581-05-5 free base) TP2212L 98.67%
a-MSH, amide Acetate(581-05-5 free base)
a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities....
Bivamelagon
T79090
MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and ere...
Bivamelagon hydrochloride
T79091
MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction. ...
IIIM-8
T79378
IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human Adult Epid...
N,N′-Diferuloylputrescine
T79996
N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation. It also considerably diminishes the protein expression of MITF an...
Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2
T80121
Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH2 is a synthetic cyclic octapeptide that exhibits melanocortin-4 receptor (MC4R) agonism and has been shown to signific...
ACTH (7-38) (human)
T80125
ACTH (7-38) (human) is a fragment (7-38) of the full human adrenocorticotropic hormone (ACTH (1-39)), also referred to as corticotropin inhibitory peptide (CIP)....
Tetrapeptide-1
T80202
Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].
TCMCB07
T80540
TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications in the...
TCMCB07 TFA
T80541
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role in manag...
Setmelanotide
T12882
Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
Adrenocorticotropic Hormone (ACTH) (4-10), human
T7627
Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
PF-07258669
T69526
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.
SHU 9119 acetate
T16879L
SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC...
Beta-MSH (1-22) (human) acetate
TP1004L
Beta-MSH (1-22) (human) acetate (Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)) , is an endogenous melanocortin-4 receptor (MC4-R) agonist.
MCL0020
TP1889
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). ...
JNJ-10229570
T5464
JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiat...
Adrenocorticotropic Hormone (ACTH) (4-10) TFA
T7627L
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .
THIQ
T8485
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
AP1189 acetate
T9596
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
a-MSH, amide Acetate(581-05-5 free base)
TP2212L
a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities....
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TargetMol