Shopping Cart

Your shopping cart is currently empty

2-MNG (Synonyms: 2MNG, 2-Mercaptonicotinoyl glycine)

Name: 2-MNG
Brand: TargetMol
SKU: T89029
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T89029 Copy Product Info

Purity: 99.17%

🥰Excellent

2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor that prevents the incorporation of certain melanin precursors into growing melanin by binding to them. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.

2-MNG

Copy Product Info

🥰Excellent

Catalog No. T89029

Synonyms 2MNG, 2-Mercaptonicotinoyl glycine

Cas No. 2101538-28-5

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
1 mg	$44	-	In Stock
5 mg	$96	-	In Stock
10 mg	$153	-	In Stock
25 mg	$309	-	In Stock
50 mg	$458	-	In Stock
100 mg	$673	-	In Stock
1 mL x 10 mM (in DMSO)	$105	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:99.17%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor that prevents the incorporation of certain melanin precursors into growing melanin by binding to them. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.
Targets&IC50	melanogenesis:49.5 μM
In vitro	2-MNG is a compound that inhibits melanogenesis with IC50 of 49.5 μM in normal human melanocytes. [1]
Synonyms	2MNG, 2-Mercaptonicotinoyl glycine

Chemical Properties

Molecular Weight	212.23
Formula	C₈H₈N₂O₃S
Cas No.	2101538-28-5
Smiles	O=C(O)CNC(=O)C1=CC=CNC1=S

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (471.19 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.7119 mL	23.5593 mL	47.1187 mL	235.5935 mL
5 mM	0.9424 mL	4.7119 mL	9.4237 mL	47.1187 mL
10 mM	0.4712 mL	2.3559 mL	4.7119 mL	23.5593 mL
20 mM	0.2356 mL	1.1780 mL	2.3559 mL	11.7797 mL
50 mM	0.0942 mL	0.4712 mL	0.9424 mL	4.7119 mL
100 mM	0.0471 mL	0.2356 mL	0.4712 mL	2.3559 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc