Glutathione Peroxidase

Glutathione peroxidase (GPx) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.

Cat. No.	Product name	CAS No.	Purity
T26389	4-POBN	5351-17-7	98%
T26389	4-POBN is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.
T12189	NBDHEX	787634-60-0	98%
T12189	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
T8375	ML-210	1360705-96-9	98%
T8375	ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity
T1296	4-Aminosalicylic acid	65-49-6	98%
T1296	Aminosalicylic Acid is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.
T0646	5-Aminosalicylic Acid	89-57-6	98%
T0646	Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the acti...
T5097	Ezatiostat	168682-53-9	98%
T5097	Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.
T4090	PF-06282999	1435467-37-0	98%
T4090	PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
T61028	Mitiperstat	1933460-19-5	98%
T61028	Mitiperstat is a potent myeloperoxidase (MPO) inhibitor that is effective in preventing cardiovascular diseases such as heart failure and coronary artery disease...
T11505	GSTO1-IN-1	568544-03-6	98%
T11505	GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM).
T5340	MPO-IN-28	37836-90-1	98%
T5340	MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
T5463	Verdiperstat	890655-80-8	98%
T5463	Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neuro...
T1258	Nabumetone	42924-53-8	98%
T1258	Nabumetone(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
T25131	AZD8309	333742-48-6	98%
T25131	AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas a...
T14379	AZD5904	618913-30-7	98%
T14379	AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat).
T3511	PF-1355	1435467-38-1	98%
T3511	PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.
T8970	ML162	1035072-16-2	98%
T8970	ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-typ...
T1659	Melatonin	73-31-4	98%
T1659	Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and...
TJS0338	4-Methylesculetin	529-84-0	98%
TJS0338	4-methylesculetin is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
T4313	Tinoridine hydrochloride	25913-34-2	98%
T4313	Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases...
T0133	Cefdinir	91832-40-5	98%
T0133	Cefdinir is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of t...