T16507 |
PF-5006739
|
1293395-67-1
|
98%
|
|
PF-5006739 is an effective and selective inhibitor of CK1δ/ε (IC50s: 3.9 nM and 17.0 nM, respectively). PF-5006739 is a potential therapeutic agent for a range o...
|
T10829 |
CKI-7 free base
|
120615-25-0
|
98%
|
|
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base...
|
T8305 |
Ellagic acid (hydrate)
|
314041-08-2
|
98%
|
|
Ellagic acid hydrate is a natural antioxidant and acts as a potent and ATP-competitive CK2 inhibitor (IC50:40 nM, Ki: 20 nM).
|
T2440 |
IC261
|
186611-52-9
|
98%
|
|
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
|
T6735 |
XL413 hydrochloride
|
2062200-97-7
|
98%
|
|
XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC 50 of 3.4 nM. XL413 (BMS-863233) hydrochloride also exh...
|
T2449 |
D4476
|
301836-43-1
|
98%
|
|
D4476 is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).
|
T14069 |
A-3 hydrochloride
|
78957-85-4
|
98%
|
|
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and c...
|
T2008 |
LY294002
|
154447-36-6
|
98%
|
|
LY294002 is an inhibitor of PI3K (IC50s: 0.5/0.57/0.97 μM for PI3Kα/δ/β in cell-free assays). It also blocks autophagosome formation.
|
T0465 |
Ellagic acid
|
476-66-4
|
98%
|
|
Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clott...
|
T6150 |
TAK-715
|
303162-79-0
|
98%
|
|
TAK-715 is a p38 MAPK inhibitor for p38α.
|
T9356 |
(E/Z)-GO289
|
694522-87-7
|
98%
|
|
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of canc...
|
T2048 |
LY-364947
|
396129-53-6
|
98%
|
|
LY364947 is a potent ATP-competitive inhibitor of TGFβR-I.
|
T7390 |
DMAT
|
749234-11-5
|
98%
|
|
DMAT is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
|
T15024 |
Silmitasertib sodium salt
|
1309357-15-0
|
98%
|
|
Silmitasertib sodium salt is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
|
T2259 |
Silmitasertib
|
1009820-21-6
|
98%
|
|
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).
|
T2695 |
TBB
|
17374-26-4
|
98%
|
|
TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
|
T60067 |
WAY-297174
|
442571-27-9
|
98%
|
|
WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.
|
T3073 |
PF-670462
|
950912-80-8
|
98%
|
|
PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
|
T64350 |
WAY-296818
|
349438-77-3
|
98%
|
|
WAY-296818 (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.
|
T71339 |
BMS-863233 HCl
|
1169562-71-3
|
98%
|
|
BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215 and...
|