j 2

HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function.

GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.

15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.

15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 µM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.

Prostaglandin J2 (PGJ2), a derivative of Prostaglandin D2 (PGD2), serves as a potent agonist for PGD2 receptors (DP), exhibiting affinity constants (K i) of 0.9 nM and 6.6 nM for hDP and hCRTH2 receptors, respectively. It activates cyclic AMP production with an EC50 of 1.2 nM, induces oxidative stress, neuronal apoptosis, and promotes the accumulation of ubiquitinated (Ub) proteins. Notably, PGJ2's neurotoxic properties are implicated in the progression of neurodegenerative diseases such as Alzheimer's (AD) and Parkinson's (PD) [1] [2] [3] [4].

GSK-J2 sodium, the sodium form of GSK-J2, is an isomer of GSK-J1 and lacks specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A [1].

Prostaglandin J2 (Standard) is a reference standard for research and analysis in studies involving Prostaglandin J2. Prostaglandin J2 (PGJ2), a derivative of Prostaglandin D2 (PGD2), serves as a potent agonist for PGD2 receptors (DP), exhibiting affinity constants (K i) of 0.9 nM and 6.6 nM for hDP and hCRTH2 receptors, respectively. It activates cyclic AMP production with an EC50 of 1.2 nM, induces oxidative stress, neuronal apoptosis, and promotes the accumulation of ubiquitinated (Ub) proteins. Notably, PGJ2's neurotoxic properties are implicated in the progression of neurodegenerative diseases such as Alzheimer's (AD) and Parkinson's (PD) [1] [2] [3] [4].

15-deoxy-Δ-12,14-Prostaglandin J2 (Standard) is a reference standard for research and analysis in studies involving 15-deoxy-Δ-12,14-Prostaglandin J2. 15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.

13,14-Dihydro-15-keto prostaglandin J2 (13,14-Dihydro-15-keto-PGJ2) is the dehydrated product of 13,14-dihydro-15-keto PGD2.

15-deoxy-Δ12,14-Prostaglandin J2 Glutathione (15-Deoxy-Δ12,14-PGJ2 Glutathione) is a non-enzymatic adduct formed from the reaction of 15-deoxy-Δ12,14-PGJ2 with glutathione. The biological properties of this compound have not yet been determined.

15-Deoxy-Δ12,14-prostaglandin J2 serinol amide (15-Deoxy-Δ12,14-PGJ2 serinol amide) is a derivative of 15-deoxy-Δ12,14-PGJ2-2-glycerol ester.

Oxmetidine mesylate is an antagonist to Histamine H2 Receptors

2-Deacetoxydecinnamoyltaxinine J is a natural product from Taxus cuspidta Sibe et Zucc.

2-Deacetoxytaxinine J shows significant in vitro activity against breast cancer cell line at a concentration of 20 microM and 10 microM in MCF-7 and MDA-MB-231 respectively.

Jak2-IN-7j is a selective Jak2 inhibitor which demonstrates a time-dependent knock-down of pSTAT5, which is a downstream target of Jak2.

Anti-SARS-CoV/SARS-CoV-2 Spike Antibody (2J777) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS SARS-CoV/SARS-CoV-2 Spike.

Anti-SARS-CoV/SARS-CoV-2 Spike Antibody (9J88) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS SARS-CoV/SARS-CoV-2 Spike.

Anti-SARS-CoV-2 Alpha Spike RBD Specific Antibody (4J592) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Alpha Spike RBD Specific.

Anti-SARS-CoV-2 Delta Spike RBD Specific Antibody (2J642) is a mouse (variable region) / human (kappa / IgG1 constant) chimeric monoclonal antibody targeting SARS-CoV-2 SARS-CoV-2 Delta Spike RBD Specific.

2,7-Dideacetoxytaxinine J is a natural product for research related to life sciences. The catalog number is TN2742 and the CAS number is 115810-14-5.

J 2931 is an inhibitor of mosquito larvae growth.

J 2644 is a bioactive chemical.

J 2922 is a bioactive chemical.

LJ-278 is a bioactive chemical.