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Cat No. | Product Name | Synonyms | Targets |
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T37859 | SY-640 | Endogenous Metabolite | |
SY-640 is an Acetamide derivative. SY-640 exhibits potent hepatoprotective effect. SY-640 reduces liver injury in mice induced by Propionibacterium acnes and Lipopolysaccharide. | |||
T20561L | BPC 157 acetate(137525-51-0 free base) | BPC157 acetate,BPC-157 acetate,Bpc 15 acetate,Bpc15 acetate,Bpc-15 acetate | Others |
BPC 157 acetate(137525-51-0 free base) is a 15-amino acid fragment of a gastric peptide (BPC) which has hepatoprotective effects. | |||
T67509 | Cholesteryl Hemisuccinate | Cholesterol hydrogen succinate | Apoptosis , DNA/RNA Synthesis , Topoisomerase |
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ... | |||
TF0106 | Cholesteryl Hemisuccinate Tris Salt | Apoptosis | |
Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing C... | |||
T32753 | Limazocic | SA-3443,SA3443,SA 3443 | |
Limazocic is a cyclic disulfide with hepatoprotective effects. | |||
T16082 | Mivotilate | YH439 | Others |
Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent. | |||
T31263 | Deanol aceglumate | Otrun,Deanolo aceglumato,Risatarun,Deanoli aceglumas | |
Deanol aceglumate is combination of deanol and N-acetyl-L-glutamic acid. deanol aceglumate can effect Hepatoprotective on stress-induced gastropathy and diabetes mellitus. | |||
T13727 | Huangjiangsu A | Others | |
Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases. Huangjiangsu A is isolated from D. villosa. | |||
T68390 | Nivocasan | ||
Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in N... | |||
T63009 | NF-κB/PON1-IN-1 | ||
NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity. | |||
T72471 | Antioxidant agent-2 | ||
Antioxidant agent-2 (comp 3c), a BBB-penetrating and selective metal ion chelator, exhibits significant neuroprotective and hepatoprotective effects, making it beneficial for Alzheimer’s disease research. | |||
T36673 | CC 401 dihydrochloride | ||
High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase... | |||
T62598 | Pitavastatin sodium | ||
Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and a potent inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. pitavastatin sodium inhibit... | |||
T7072 | Pitavastatin | ||
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC 50 of 5.8 nM. It also acts as an effic... | |||
T36055 | Nitisinone-13C6 | Nitisinone-13C6 | |
Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyr... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T80778 | Weak Hepatoprotective agent-1 | ||
Compound 11, labeled as a weak Hepatoprotective agent-1, is a naturally occurring substance extracted from the fruits of Arctium lappa L. It demonstrates modest hepatoprotective effects when applied at a concentration of... | |||
T7934 | 7-Methylcoumarin | Others | |
7-Methylcoumarin with strong hepatoprotective activity. | |||
T3416 | Aucubin | Aucuboside,Rhinanthin | IL Receptor , NF-κB , Antibacterial |
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities. | |||
T7052 | Gnetol | Tyrosinase , COX , HDAC , AChR | |
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ... | |||
TN2062 | Phyllanthin | NF-κB | |
Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp. | |||
TN1035 | Irisolidone | IL Receptor , NF-κB , Chloride channel | |
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. | |||
T0795 | Rutin | Quercetin 3-O-rutinoside,Rutoside | Beta Amyloid , Prostaglandin Receptor , Autophagy |
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties. | |||
T22417 | Rutin hydrate | Rutoside,Sophorin,Quercetin-3-O-rutinoside | Beta Amyloid , Others , Autophagy |
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit. | |||
T7917 | 4'-Hydroxychalcone | 2-Benzal-4-Hydroxyacetophenone | Proteasome |
4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity | |||
T6S1525 | 3,4-Dicaffeoylquinic acid | Isochlorogenic acid B | Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite |
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity. | |||
T2950 | Schisandrin | Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol | Autophagy |
Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects. | |||
TN1118 | Tormentic acid | Immunology/Inflammation related | |
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties, | |||
TN1027 | β-Amyrin | beta-Amyrin | Beta Amyloid |
β-Amyrin (beta-Amyrin) has antiviral, hepatoprotective, antinociceptive, anti-inflammatory | |||
TN7039 | Celosin H | Others | |
Celosin H is a novel hepatoprotective triterpenoid saponin isolated from the methanol extract of Celosiae Semen. | |||
T3321 | Oleanonic acid | 3-Oxooleanolic acid,3-Oxoolean-12-en-28-oic Acid,Oleanonic Acid,3-Ketooleanolic Acid | HIV Protease |
Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties. | |||
TC0039 | Vasicinone | Others | |
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer... | |||
T5S1408 | Pteryxin | (+)-Pteryxin | Others , AChE |
(+)-Pteryxin ((+)-Pteryxin) has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity. | |||
TN1656 | Ganoderenic acid A | Others | |
Ganoderenic acid A has a potent hepatoprotective, and cytotoxic effects, it shows inhibitory activity on human aldose reductase in vitro. | |||
T6S0413 | Pectolinarigenin | Pectolinaringenin | Others , Lipoxygenase , COX |
1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in ... | |||
T6S2252 | Sweroside | Others | |
1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells and rat osteoblasts. | |||
T67709 | Hispolon | Others | |
Hispolon is a polyphenol. Hispolon can be isolated from Phellinus linteus. Hispolon exhibits anticancer, antidiabetic, antiviral, hepatoprotective, antioxidant, and anti-inflammatory activities. | |||
TN2179 | Saponarin | Petrocomoside,Saponaretin-7-O-glucoside,Isovitexin-7-O-glucoside | ERK , P450 , NF-κB , AMPK |
Saponarin (Petrocomoside) shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage. | |||
TN2225 | Soyasapogenol B | Apoptosis , Autophagy | |
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2. | |||
TN1079 | Deoxyelephantopin | NF-κB | |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling | |||
T8288 | 14-Deoxyandrographolide | Apoptosis , Others | |
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release. | |||
TN1472 | Cassiaside | Beta-Secretase , BACE | |
Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (... | |||
T0632 | 3,4,5-Trimethoxybenzoic acid | Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid | Antioxidant |
3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It... | |||
T5712 | Zerumbone | Antioxidant , HSV | |
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a... | |||
T1716 | Echinacoside | Reactive Oxygen Species , Wnt/beta-catenin | |
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat... | |||
T3S2296 | Gardenoside | Others | |
Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB act... | |||
TN1557 | Decursinol angelate | ERK , VEGFR , PKC , JNK | |
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an... | |||
T3019 | Physcion | Physcione,Parietin,Rheochrysidin | Dehydrogenase , Antibacterial |
Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM... | |||
TN2091 | Polygalacin D | Apoptosis , IAP | |
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi... | |||
T3S0645 | N-trans-Feruloyltyramine | Feruloyltyramine,N-Feruloyltyramine,Moupinamide | Others , COX |
1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s... | |||
T2787 | Picroside I | 6'-Cinnamoylcatalpol | MMP , STAT |
Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ... | |||
T4115 | Auraptene | 7-geranyloxycoumarin | MMP , BACE |
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le... | |||
T6S0117 | Avicularin | Fenicularin | ERK |
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX... | |||
T5S2254 | Swertianolin | Bellidifolin-8-O-Glucoside | Others , HBV , Antibacterial , AChE |
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin... | |||
T4749 | Squalene | Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene | Reactive Oxygen Species , Endogenous Metabolite , Antifungal |
Squalene (AddaVax) is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran, wheat germ, and olives. All hi... | |||
T2909 | Fraxetin | 7,8-dihydroxy-6-methoxy coumarin | Apoptosis , Others |
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m... | |||
T3822 | Bellidifolin | Bellidifoline,Bellidifolium | Others , HIV Protease |
Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela... | |||
T41095 | (E)-3-(4-Methoxyphenyl)acrylic acid | Glucosidase | |
(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid ha... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T3S1416 | Decursin | Decursinol angelate,(+)-Decursin | Apoptosis , PKC |
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ... | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T1660 | Silibinin | Silibinin A,Silybin,Silymarin I | Reactive Oxygen Species , Autophagy |
Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an... | |||
T9113 | Myristicin | Myristicine | IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase |
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ... | |||
T5S1172 | Tiliroside | Tribuloside | Antioxidant |
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati... | |||
TN4560 | Methylisopelletierine | Others | |
N-Methylisopelletierine has hepatoprotective activity. | |||
TN6639 | Suspenoidside B | ||
Suspenoidside B possesses strong hepatoprotective activities against the damage in HepG2 cell. | |||
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