facilitate

α-Cyano-4-hydroxycinnamic acid (α-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1), which blocks pyruvate transport in rat heart mitochondria (IC50: 1.5 μM).

Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeletal muscle relaxation.

Casanthranol, a concentrated mixture of anthranol glycosides from the dried bark of Rhamnus p. (cascara sagrada), is a stimulant laxative used to alleviate constipation and other medical conditions by increasing muscle contractions in the intestinal wall to facilitate bowel movements.

Proteinases are enzymes that catalyse the breakdown of proteins. Proteinases are involved in many biological functions, including the digestion of ingested proteins, the breakdown of old proteins, and cell signalling. They also facilitate the formation of new protein products.

D-Glucuronic acid sodium salt monohydrate (Sodium D-glucuronate) is a carboxylic acid that is highly soluble in water. In humans, glucuronic acid often binds to toxic substances to facilitate elimination and to hormones to aid in their transport.

Oxytocin (Syntocinon) is a mammalian neuropituitary hormone, a pleiotropic hypothalamic peptide and ligand for the oxytocin receptor, which contributes to labor, lactation, and pro-social behavior. Oxytocin has the ability to stimulate mammary secretion of breast milk, promote contraction of uterine smooth muscle during labor, and facilitate mothering.

Coumarin 6 (Coumarin VI) is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.

1, 4-butanediamine is an aliphatic diamine compound that can be used as an analytical reagent to assist in precise detection experiments and also as a dye intermediate to facilitate the synthesis of various functional dyes.

Acid-PEG3-C2-Boc, a PEG- and alkyl/ether-based PROTAC linker, is utilized in PROTAC synthesis to facilitate the degradation of EGFR and inhibit mTOR[1][2].

Amino-PEG9-amine is a PEG-based linker used in PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Aminooxy-PEG7-methane is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

BDP FL-PEG5-azide is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG5-azide is a PEG-based linker for PROTACs, joining two crucial ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-Mal-PEG3 is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation through the ubiquitin-proteasome system within cells.

BnO-PEG4-OH is a PEG-based linker for PROTACs [degrader molecules], joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system.

Bromo-PEG5-bromide, a PEG-based linker for PROTACs, connects two essential ligands to facilitate the formation of PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

endo-BCN-PEG3-acid is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable linker for antibody-drug conjugates (ADCs)[1], used in the synthesis of ADCs to facilitate the covalent attachment of drugs to antibodies through stable amide bond formation.

m-PEG3-CH2COOH is a PEG-based linker used in PROTACs that connects two essential ligands to facilitate the formation of PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

N-Boc-N-bis-PEG5 is a PEG-based linker for PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker used in the synthesis of PROTACs and antibody-drug conjugates (ADCs) [1, 2], serving as a cleavable ADC linker to facilitate drug-antibody conjugation for targeted delivery [2].

Propargyl-PEG4-Boc is a PEG-based linker for PROTACs, joining two essential ligands to facilitate PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG3-methane is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation by utilizing the ubiquitin-proteasome system within cells.