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(7)
By Target- DNA/RNA Synthesis
- PARP(4)
- Topoisomerase(4)
- Apoptosis(3)
- ADC Cytotoxin(2)
- DNA-PK(2)
- 5-HT Receptor(1)
- ATM/ATR(1)
- Anti-infection(1)
- Others(42)
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VX-984
M9831
T110671476074-39-1
VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.
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