ep3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T80383	EP3
	EP3, an antimicrobial peptide, exhibits both antibacterial and antifungal activities, effectively inhibiting E. gallinarum, P. pyocyanea, A. baumanii, and K. terrigena with a minimum inhibitory concentration (MIC) of 12....
T77630	EP3 antagonist 4		Prostaglandin Receptor
	EP3 antagonist 4 is an EP3 antagonist that inhibits hEP with a Ki of 2 nM. EP3 antagonist 4 showed low in vivo clearance, high oral AUC and good bioavailability in complete PK studies in rats. EP3 antagonist 4 can be use...		Prostaglandin Receptor
T61357	EP3 antagonist 3
	EP3 antagonist 3 (compound 2) is a highly effective and specific antagonist of the EP3 receptor. It displays significant oral bioavailability and exhibits a strong pKi value of 8.3. Furthermore, EP3 antagonist 3 possesse...
T5841	Travoprost	Flu-Ipr,Fluprostenol isopropyl ester,AL6221	Prostaglandin Receptor
	Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.		Prostaglandin Receptor
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T7264	CBP/EP300-IN-1		Epigenetic Reader Domain
	CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.		Epigenetic Reader Domain
T73920	Ep300/CREBBP-IN-8
	Ep300/CREBBP-IN-8 (Example 37), a potent and orally active inhibitor of both Ep300 and CREBBP, exhibits IC50 values of 0.014 μM and 0.018 μM, respectively. This compound is utilized in cancer research [1].
T73923	Ep300/CREBBP-IN-4
	Ep300/CREBBP-IN-4 (Example 56), a highly effective inhibitor targeting both Ep300 and CREBBP, exhibits IC50 values of 0.024 μM and 0.064 μM, respectively. This compound is utilized in cancer research [1].
TP1614	AtPep3 TFA (902781-14-0 free base)	AtPep3 TFA
	AtPep3 TFA is a hormone-like peptide that plays a role in the salinity stress tolerance of plants.
TP1539	AtPep3
	AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants.
T82942	AtPep3 TFA
	AtPep3 TFA, a hormone-like peptide, enhances plant salinity tolerance and inhibits salt-induced chlorophyll bleaching in seedlings [1].
T73576	EP39
	EP39, a potent HIV-1 maturation inhibitor, binds to the QVT motif within the SP1 domain of Gag, reducing the dynamics at the CA-SP1 junction and disrupting the coil-helix equilibrium adjacent to the SP1 domain by stabili...
T73922	Ep300/CREBBP-IN-3
	Ep300/CREBBP-IN-3 (Example 61), a potent inhibitor of Ep300 and CREBBP, exhibits IC50 values of 0.056 μM and 0.095 μM, respectively. This compound is applicable in cancer research [1].
T73921	Ep300/CREBBP-IN-2
	Ep300/CREBBP-IN-2 (Example 73), a powerful and orally bioavailable inhibitor targeting Ep300 and CREBBP, demonstrates IC50 values of 0.052 μM and 0.148 μM, respectively. This compound is employed in cancer research [1].
T15108	DG-041		Prostaglandin Receptor
	DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...		Prostaglandin Receptor
T14148	AH 6809		Prostaglandin Receptor
	AH 6809 is an antagonist of EP and DP receptor(with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively). AH 6809 has a Ki of 350 nM for mouse EP2 receptor.		Prostaglandin Receptor
T14975	CJ-42794	CJ-042794	Others
	CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...		Others
T11211	EP4 receptor antagonist 1		Prostaglandin Receptor
	EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and...		Prostaglandin Receptor
T63349	Treprostinil diethanolamine	UT-15C	Prostaglandin Receptor
	Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FPKi, respectively. Treprostinil diethanolamine i...		Prostaglandin Receptor
T3306	PF-04418948	PF 04418948,PF04418948	Prostaglandin Receptor
	PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers...		Prostaglandin Receptor