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DNA Alkylator/Crosslinker

Cat. No. Product name CAS No. Purity Chemical Structure
T16871 Semustine 13909-09-6 98%
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
T0164 Oxaliplatin 61825-94-3 98%
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
T8554 KCC-07 315702-75-1 98%
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD...
T1055 Ifosfamide 3778-73-2 98%
Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mus...
T0707 Cyclophosphamide hydrate 6055-19-2 98%
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T1564 Cisplatin 15663-27-1 98%
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
T1058 Carboplatin 41575-94-4 98%
Carboplatin is an organoplatinum compound that possesses antineoplastic activity.
T5017 Nimustine Hydrochloride 55661-38-6 98%
Nimustine has been used in trials studying the treatment of Glioblastoma.
T1507 Streptozocin 18883-66-4 98%
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
T1178 Temozolomide 85622-93-1 98%
Temozolomide is a DNA alkylating agent interfering with DNA replication.
T0707L Cyclophosphamide 50-18-0 98%
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T22857 Illudin S 1149-99-1 98%
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
T4368 Miriplatin 141977-79-9 98%
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
T17159 Treosulfan 299-75-2 98%
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
T1250 Thio-TEPA 52-24-4 98%
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
T7221 Satraplatin 129580-63-8 98%
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
T1798 RITA 213261-59-7 98%
RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...
T4350 Palifosfamide 31645-39-3 98%
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
T4570 Pipobroman 54-91-1 98%
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...
T4459 PK11000 38275-34-2 98%
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
Semustine
T16871
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
Oxaliplatin
T0164
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
KCC-07
T8554
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD...
Ifosfamide
T1055
Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mus...
Cyclophosphamide hydrate
T0707
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
Cisplatin
T1564
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
Carboplatin
T1058
Carboplatin is an organoplatinum compound that possesses antineoplastic activity.
Nimustine Hydrochloride
T5017
Nimustine has been used in trials studying the treatment of Glioblastoma.
Streptozocin
T1507
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
Temozolomide
T1178
Temozolomide is a DNA alkylating agent interfering with DNA replication.
Cyclophosphamide
T0707L
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
Illudin S
T22857
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
Miriplatin
T4368
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
Treosulfan
T17159
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
Thio-TEPA
T1250
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
Satraplatin
T7221
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
RITA
T1798
RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...
Palifosfamide
T4350
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
Pipobroman
T4570
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...
PK11000
T4459
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
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