T16871 |
Semustine
|
13909-09-6
|
98%
|
|
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
|
T22857 |
Illudin S
|
1149-99-1
|
98%
|
|
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
|
T17212 |
VAL-083
|
23261-20-3
|
98%
|
|
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
|
T4459 |
PK11000
|
38275-34-2
|
98%
|
|
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
|
T1488 |
Procarbazine hydrochloride
|
366-70-1
|
98%
|
|
Procarbazine Hydrochloride is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cyt...
|
T4570 |
Pipobroman
|
54-91-1
|
98%
|
|
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...
|
T4350 |
Palifosfamide
|
31645-39-3
|
98%
|
|
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
|
T8380 |
Bendamustine
|
16506-27-7
|
98%
|
|
Bendamustine for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
|
T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
|
T4368 |
Miriplatin
|
141977-79-9
|
98%
|
|
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
|
T0095 |
Bendamustine hydrochloride
|
3543-75-7
|
98%
|
|
Bendamustine hydrochloride (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
|
T1798 |
RITA
|
213261-59-7
|
98%
|
|
RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...
|
T4558 |
Trioxsalen
|
3902-71-4
|
98%
|
|
Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation ...
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
T5017 |
Nimustine Hydrochloride
|
55661-38-6
|
98%
|
|
Nimustine has been used in trials studying the treatment of Glioblastoma.
|
T17159 |
Treosulfan
|
299-75-2
|
98%
|
|
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T1507 |
Streptozocin
|
18883-66-4
|
98%
|
|
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
|
T0975 |
Chlorambucil
|
305-03-3
|
98%
|
|
Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, result...
|
T1564 |
Cisplatin
|
15663-27-1
|
98%
|
|
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
|
T0707 |
Cyclophosphamide hydrate
|
6055-19-2
|
98%
|
|
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
|