T16871 |
Semustine
|
13909-09-6
|
98%
|
|
Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for ...
|
T0164 |
Oxaliplatin
|
61825-94-3
|
98%
|
|
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
|
T8554 |
KCC-07
|
315702-75-1
|
98%
|
|
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD...
|
T1055 |
Ifosfamide
|
3778-73-2
|
98%
|
|
Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mus...
|
T0707 |
Cyclophosphamide hydrate
|
6055-19-2
|
98%
|
|
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
|
T1564 |
Cisplatin
|
15663-27-1
|
98%
|
|
Cisplatin, a DNA-crosslinking agent, is able to suppress DNA synthesis by conforming DNA adducts in cancer cells.
|
T1058 |
Carboplatin
|
41575-94-4
|
98%
|
|
Carboplatin is an organoplatinum compound that possesses antineoplastic activity.
|
T5017 |
Nimustine Hydrochloride
|
55661-38-6
|
98%
|
|
Nimustine has been used in trials studying the treatment of Glioblastoma.
|
T1507 |
Streptozocin
|
18883-66-4
|
98%
|
|
Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animal...
|
T1178 |
Temozolomide
|
85622-93-1
|
98%
|
|
Temozolomide is a DNA alkylating agent interfering with DNA replication.
|
T0707L |
Cyclophosphamide
|
50-18-0
|
98%
|
|
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
|
T22857 |
Illudin S
|
1149-99-1
|
98%
|
|
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties.
|
T4368 |
Miriplatin
|
141977-79-9
|
98%
|
|
Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
|
T17159 |
Treosulfan
|
299-75-2
|
98%
|
|
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
|
T1250 |
Thio-TEPA
|
52-24-4
|
98%
|
|
Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
|
T7221 |
Satraplatin
|
129580-63-8
|
98%
|
|
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against...
|
T1798 |
RITA
|
213261-59-7
|
98%
|
|
RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 i...
|
T4350 |
Palifosfamide
|
31645-39-3
|
98%
|
|
Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to...
|
T4570 |
Pipobroman
|
54-91-1
|
98%
|
|
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essen...
|
T4459 |
PK11000
|
38275-34-2
|
98%
|
|
PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.
|