Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

CRFR

Corticotropin-releasing hormone receptor 1 (CRHR1) is a protein, also known as CRF1, with the latter (CRF1) now being the IUPHAR-recommended name. In humans, CRF1 is encoded by the CRHR1 gene.

Urotensin I acetate (83930-33-0 Free base)
TP1199L
Urotensin I acetate (83930-33-0 Free base) is a CRF-like neuropeptide (natural product), a CRF receptor agonist (EC50 as low as 3.5 pM for hCRF1, Ki=0.4 nM), with high affinity and receptor subtype selectivity, used for CRF receptor functional research.
  • $250
In Stock
Size
QTY
TargetMol | Inhibitor Hot
α-helical CRF 9-41 acetate
α-helical CRF 9-41 acetate(90880-23-2 Free base)
TP2048L
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).
  • $219
In Stock
Size
QTY
Urocortin (rat) acetate
Urocortin (rat) acetate (171543-83-2 Free base)
TP1020L
Urocortin (rat) acetate is a potent, selective CRFR agonist with Ki values of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α, and mouse CRF2β, respectively. Urocortin (rat) acetate exhibits cardioprotective, anti-inflammatory, and immunomodulatory activities. Urocortin (rat) acetate can be used in cardiovascular protection and immune-inflammatory research.
  • $159
Inquiry
Size
QTY
K 41498 aceate
TP2009L
K41498 acetate, an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. K41498 acetate is a potent and highly selective antagonist CRF2 receptor with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively.
  • $338
In Stock
Size
QTY
Urocortin, human
Urocortin (human), Human urocortin I, Human urocortin 1, Human urocortin
TP1021176591-49-4
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
  • $98
Inquiry
Size
QTY
Antalarmin hydrochloride
T22577220953-69-5
Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.
  • $30
In Stock
Size
QTY
Verucerfont
NBI77860, GSK561679
T7361885220-61-1
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
  • $58
In Stock
Size
QTY
(R)-Crinecerfont
(R)-SSR-125543
T601262649012-21-3In house
(R)-Crinecerfont is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.
  • $117
In Stock
Size
QTY
CP 376395
CP-316311
T4329175140-00-8
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
  • $35
In Stock
Size
QTY
CP 316311
T15008175139-41-0In house
CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression.
  • $293 TargetMol
In Stock
Size
QTY
Astressin acetate
Astressin acetate (170809-51-5 Free base)
TP1448L
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM).
  • $236
In Stock
Size
QTY
NBI-27914
NBI27914
T62444184241-44-9
NBI-27914 is a selective and non-peptide CRFR1 (corticotropin-releasing factor receptor 1) antagonist with analgesic effects, capable of blocking CRF-induced anxiety.
  • $39
In Stock
Size
QTY
R121919
NBI30775
T16713195055-03-9
R121919 (NBI30775) is a potent small molecule antagonist of the adrenocorticotropic hormone-releasing factor receptor 1 (CRF1), demonstrating antidepressant and anxiolytic activity, and inhibiting the CRF1 receptor, CRF2 receptor, and CRF-binding proteins.
  • $89
In Stock
Size
QTY
Corticotropin-releasing factor (human) acetate
Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)
TP1144L
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary.
  • $148
In Stock
Size
QTY
CRF (6-33) acetate(120066-38-8 free base)
TP2047L
CRF (6-33) acetate is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
  • $223
In Stock
Size
QTY
Crinecerfont
SSR-125543A, SSR125543A, SSR-125543, SSR125543, SSR 125543A, SSR 125543
T31095752253-39-7In house
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
  • $93
In Stock
Size
QTY
Pexacerfont
BMS-562086
T16475459856-18-9
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
  • $40
In Stock
Size
QTY
Tetracosactide acetate
T3566460189-34-6
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland.
  • $30
In Stock
Size
QTY
Tetracosactide
Tetracosactrin
TP103116960-16-0
Tetracosactide (Tetracosactrin) (INN) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.
  • $58
In Stock
Size
QTY
Tildacerfont
T262781014983-00-6
Tildacerfont is an antagonist of CRF1 and reduces the levels of adrenocorticotropic hormone and adrenal androgen. Tildacerfont can be used in studies about congenital adrenal hyperplasia.
  • $79
In Stock
Size
QTY
Antalarmin
T70433157284-96-3
Antalarmin is a selective and potent corticotropin-releasing factor receptor 1 (CRHR1) antagonist that crosses the blood-brain barrier and blocks CRF activation and carrageenan-induced subcutaneous inflammation in rats.
  • $78
In Stock
Size
QTY
CP 154526 hydrochloride
CP-154526 hydrochloride, CP154526 hydrochloride
T22682257639-98-8
CP 154526 hydrochloride is a blood-brain barrier-penetrant, selective CRF1 (corticotropin-releasing factor receptor 1) antagonist (Ki = 2.7 nM) exhibiting thousands of times greater selectivity for CRF1 over CRF2, with anxiolytic and antidepressant activities.
  • $45
In Stock
Size
QTY
DMP 696
T15145202578-52-7
DMP 696 is a selective antagonist of corticotropin-releasing hormone receptor 1. It is used for the treatment of anxiety and depression.
  • $1,520
6-8 weeks
Size
QTY
Stressin I
TP2125
Potent and selective corticotropin releasing factor receptor-1 (CRF1) agonist (Ki values are 1.5 and 224 nM for CRF1 and CRF2 receptors respectively). Increases ACTH levels and increases faecal pellet output in vivo following i.p. administration.
  • $1,119
Inquiry
Size
QTY