Androgen Receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

Cat. No.	Product name	CAS No.	Purity
TN1663	Ganoderic acid DM	173075-45-1	98%
TN1663	Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 ...
TN1061	Ganoderol B	104700-96-1	98%
TN1061	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate ...
T15749	LGD-2226	328947-93-9	98%
T15749	LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle...
T15816	LY341495	201943-63-7	98%
T15816	LY341495 is an antagonist of metabotropic glutamate receptor (IC50s: 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively).
T10946	D4-abiraterone	154229-21-7	98%
T10946	D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abira...
TN4774	Physalin A	23027-91-0	98%
TN4774	Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
T14675	BMS-564929	627530-84-1	98%
T14675	BMS-564929 is an agonist of androgen receptor (AR, Ki of 2.11±0.16 nM).
T14843	Bifluranol	34633-34-6	98%
T14843	Bifluranol is an anti-androgen.
TMA1012	Ganoderiol F	114567-47-4	98%
TMA1012	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
T19449	N-desmethyl Enzalutamide D6	T19449	98%
T19449	N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
T0380	Bicalutamide	90357-06-5	99.97%
T0380	Bicalutamide, a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor bind...
T68020	Zanoterone	107000-34-0	99.96%
T68020	Zanoterone is an AR antagonist (androgen receptor).Zanoterone has antitumor activity for the treatment of genitourinary disorders and oncological disorders and m...
T0419	Testosterone propionate	57-85-2	99.92%
T0419	Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland...
T0489	Flutamide	13311-84-7	99.92%
T0489	Flutamide is an antiandrogen with about the same potency as cyproterone in rodent and canine species.
T9179	CLP-3094	312749-73-8	99.84%
T9179	CLP-3094 is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selecti...
TN1370	Allura Red AC	25956-17-6	99.82%
TN1370	Allura Red AC is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to ...
T2236	RU 58841	154992-24-2	99.77%
T2236	RU 58841 is a specific androgen receptor antagonist or anti-androgen; RU 58841 has a significant effect on hair regrowth.
TQ0209	Ailanthone	981-15-7	99.71%
TQ0209	Ailanthone is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated AR splice variants (IC50: 309 n...
T13272	UT-155	2031161-35-8	99.63%
T13272	UT-155 is a selective and potent antagonist of the androgen receptor (AR) (Ki: 267 nM for UT-155 binding to AR-LBD).
T0476	Spironolactone	52-01-7	99.63%
T0476	Spironolactone is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.