Androgen Receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

Cat. No.	Product name	CAS No.	Purity
T14843	Bifluranol	34633-34-6	98%
T14843	Bifluranol is an anti-androgen.
TN4774	Physalin A	23027-91-0	98%
TN4774	Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
T19449	N-desmethyl Enzalutamide D6	T19449	98%
T19449	N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
TN1061	Ganoderol B	104700-96-1	98%
TN1061	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate ...
TN1663	Ganoderic acid DM	173075-45-1	98%
TN1663	Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 ...
T10946	D4-abiraterone	154229-21-7	98%
T10946	D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abira...
T15816	LY341495	201943-63-7	98%
T15816	LY341495 is an antagonist of metabotropic glutamate receptor (IC50s: 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively).
TN1370	Allura Red AC	25956-17-6	98%
TN1370	Allura Red AC and amaranth are very important food azo dyes used in food, drug, paper, cosmetic and textile industries.
T15749	LGD-2226	328947-93-9	98%
T15749	LGD-2226 is a selective and orally active androgen receptor modulator (EC50: 0.2 nM, Ki: 1.5 nM for the human androgen receptor). LGD-2226 can be used for muscle...
TN2245	Sunset Yellow FCF	2783-94-0	98%
TN2245	Sunset yellow FCF and Brilliant Blue FCF are used as colorant food additives in many food products, they can have cytotoxic and genotoxic potential, it care must...
T14675	BMS-564929	627530-84-1	98%
T14675	BMS-564929 is an agonist of androgen receptor (AR, Ki of 2.11±0.16 nM).
TMA1012	Ganoderiol F	114567-47-4	98%
TMA1012	Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
T8860	DSRM-3716	58142-99-7	98%
T8860	Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a...
T39695	ARD-2128	2222111-87-5	98%
T39695	ARD-2128 is a highly potent, orally bioavailable PROTAC degrader of androgen receptor (AR). ARD-2128 effectively reduces AR protein, suppresses AR-regulated gene...
TN1067	Galloylpaeoniflorin	122965-41-7	98%
TN1067	6'-O-Galloylpaeoniflorin (GPF) may be developed as a cytoprotector against ROS-mediated oxidative stress
T9752	3-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile	2759137-87-4	98%
T9752	3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.
T11410L	GLPG0492	1215085-92-9	98%
T11410L	GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic act...
T24943	VPC-14228	19983-28-9	98%
T24943	VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.
T20761	RU 59063	155180-53-3	98%
T20761	RU 59063 is a prototype of high-affinity nonsteroidal androgen receptor (AR) ligands.
T20625	Prochloraz	67747-09-5	98%
T20625	Prochloraz, a broad-spectrum contact imidazole fungicide, is used against several diseases in wheat, barley, and oleaginous plants but also for the treatment of ...