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Bifluranol

Name: Bifluranol
Brand: TargetMol
SKU: T14843
Price: 91 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14843Cas No. 34633-34-6

Alias BX341

Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).

Bifluranol

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Purity: 99.86%

Catalog No. T14843Alias BX341Cas No. 34633-34-6

Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$91	In Stock	In Stock
5 mg	$227	In Stock	In Stock
10 mg	$371	In Stock	In Stock
25 mg	$738	In Stock	In Stock
50 mg	$1,190	In Stock	In Stock
100 mg	$1,600	-	In Stock
200 mg	$2,160	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH).
In vivo	Bifluranol has been studied for its absorption, distribution, and excretion in mouse, rat, ferret, and dog. Following oral administration, Bifluranol is readily absorbed, but its blood concentrations are low due to hepatic uptake and biliary excretion. After the intravenous administration of [3H]Bifluranol at doses of 200 μg/kg in rats and 60 μg/kg in ferrets, the blood concentrations of 3H decline rapidly during the first 2 to 3 hours. The decrease is more rapid in females (18 min for rats, 30 min for ferrets) than in males (1.0 h for rats, 1.4 h for ferrets). This initial rapid decline is followed by a much slower decrease (40 h for rats, 20 h for ferrets) to concentrations at 96 hours of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret)[1].
Synonyms	BX341

Chemical Properties

Molecular Weight	292.32
Formula	C₁₇H₁₈F₂O₂
Cas No.	34633-34-6
Smiles	CC[C@H]([C@H](C)c1ccc(O)c(F)c1)c1ccc(O)c(F)c1
Relative Density.	1.221g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (307.88 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.29 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4209 mL	17.1045 mL	34.2091 mL	171.0454 mL
5 mM	0.6842 mL	3.4209 mL	6.8418 mL	34.2091 mL
10 mM	0.3421 mL	1.7105 mL	3.4209 mL	17.1045 mL
20 mM	0.1710 mL	0.8552 mL	1.7105 mL	8.5523 mL
50 mM	0.0684 mL	0.3421 mL	0.6842 mL	3.4209 mL
100 mM	0.0342 mL	0.1710 mL	0.3421 mL	1.7105 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc